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Now showing items 41-50 of 54
NOVEL MECHANISMS GOVERNING SKELETAL MUSCLE MITOCHONDRIAL BIOENERGETICS : OXPHOS EFFICIENCY AND cAMP/PKA SIGNALING
(East Carolina University, 2014)
Understanding the regulation of cellular metabolism is paramount to treating the growing prevalence of metabolic disease worldwide. In cellular metabolism, mitochondrial oxidative phosphorylation (OXPHOS) plays a key role ...
Effects of a before school physical activity program on physical activity, musculoskeletal fitness, and cognitive function
(East Carolina University, 2015)
Regular physical activity is important for everybody, but may be especially beneficial for children. Despite this, most children in the United States do not meet physical activity recommendations. Schools are a prime ...
The Relationship between Gait Biomechanics and Body Mass Index
(East Carolina University, 2014)
Walking gait is one of the basic components of human movements. With the rising obesity epidemic and implied health complications, it is pertinent to examine the relationship between body mass index and the joint torques ...
VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING
(East Carolina University, 2012)
Mean arterial pressure (MAP) is regulated through changes in cardiac output (Q) and total peripheral resistance (TPR), where Q = heart rate (HR) x stroke volume (SV). Healthy heart rhythms have inherent variability and a ...
The Effects of Quadriceps Strengthening Exercise on Quadriceps Muscle Biomechanics During Locomotion in Adults with Knee Osteoarthritis
(East Carolina University, 2013)
Knee Osteoarthritis (OA) is a disease characterized by knee joint deterioration and pain, while also being associated with altered knee joint mechanics and quadriceps strength deficits. Research investigating the effects ...
SKELETAL MUSCLE METABOLIC FLEXIBILITY IMPAIRMENTS IN RESPONSE TO LIPID WITH OBESITY : EFFECT OF EXERCISE TRAINING
(East Carolina University, 2012)
Obese individuals exhibit skeletal muscle metabolic inflexibility by failing to increase fat oxidation and genes linked with mitochondrial biogenesis in response to a high-fat diet (HFD) and lipid incubation in cell culture. ...
Proximal vs. Distal Fascicle Behavior within the Biceps Femoris Long Head at Different Muscle Activation Levels
(East Carolina University, 2013)
Hamstring strains have been shown to occur more often in the long head of the biceps femoris (BFLH) than the semitendinosus and semimembranosus, with most injuries occurring in the proximal half of the BFLH. Muscle modeling ...
Paired Effects of Dietary Leucine Supplementation and Overload on Protein Translational Signaling and Hypertrophy in Aged Rat Skeletal Muscle
(East Carolina University, 2012)
Sarcopenia is an age-associated disorder that causes loss of skeletal muscle mass, particularly in type II (fast-twitch) muscle fibers. This loss in muscle mass can cause disability, reductions in the quality of life, and ...
The Region Specific Influence of Estradiol on In-Vivo Lipolysis in Subcutaneous Adipose Tissue in Overweight-to-Moderately-Obese Premenopausal Women
(East Carolina University, 2012)
Premenopausal women demonstrate preferential accumulation of adiposity in the gynoid region, a distribution which shifts towards the abdominal region after the menopausal transition. Although estrogen is implicated as a ...
EFFECT OF A TELEPHONE-BASED INTERVENTION ON PHYSICAL ACTIVITY AND COMPONENTS OF THE METABOLIC SYNDROME IN ADOLESCENTS
(East Carolina University, 2013)
The purpose of this study was to determine the effects of a two month telephone-based intervention in obese adolescents (BMI percentile [greater than or equal to] 95th percentile) on physical activity habits and motivation ...