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Now showing items 61-70 of 219
Motility and chemotaxis in the Lyme disease spirochete Borrelia burgdorferi : role in pathogenesis
(East Carolina University, 2016-08-18)
Lyme disease is the most prevalent vector-borne disease in United States and is caused by the spirochete Borrelia burgdorferi. The disease is transmitted from an infected Ixodes scapularis tick to a mammalian host. B. ...
CRISPR/Cas9 knockout of HAS2 in rat chondrosarcoma chondrocytes demonstrates the requirement of hyaluronan for aggrecan retention
(East Carolina University, 2016-12-15)
Hyaluronan (HA) plays an essential role in cartilage where it functions to retain aggrecan. Previous studies suggested that aggrecan is anchored indirectly to the plasma membrane of chondrocytes via its binding to ...
Toxic Effects of Chlorpyrifos Exposure on Development of Caenorhabditits Elegans
(East Carolina University, 2016-12-15)
Chlorpyrifos is a commonly utilized organophosphate pesticide, and as recently as 2007, was the most commonly used insecticide within the United States. Its ubiquity is concerning given its potential to cause developmental ...
Massive open online courses and completion rates: does academic readiness and its factors influence completion rates in MOOCs?
(East Carolina University, 2016-12-06)
With the increase in the cost of an education and the flat employment rate, many institutions and students are looking to online learning to solve this academic dilemma. Online education is thought to be a low-cost academic ...
AN INVESTIGATIVE STUDY OF THE NEUROPSYCHOLOGICAL AND NEUROPHYSIOLOGICAL FEATURES OF SUBJECTIVE SLEEP QUALITY
(East Carolina University, 2016-12-06)
Background: Disordered sleep is a national health issue affecting an estimated 50-70 million US adults. The documented consequences of disordered sleep include impaired daily function, increased risk for chronic health ...
Predicting length of treatment involvement of substance using perinatal women in an integrated inpatient healthcare program
(East Carolina University, 2016-12-16)
Services for perinatal (pregnant and one year postpartum) women are limited, and inpatient settings where women receive substance abuse services specific to the perinatal population, although ideal, are rare in eastern ...
PERCEIVED EFFECTIVENESS OF A DRIVING AND COMMUNITY MOBILITY BOOTCAMP FOR INDIVIDUALS WITH AUTISM SPECTRUM DISORDER
(East Carolina University, 2016-12-15)
This study was designed to determine the perceived effectiveness of a driving and community mobility Bootcamp for young adults with high functioning autism spectrum disorder (HFASD). Seven participants and their parents ...
EXPLORING INTERRALTIONSHIPS BETWEEN INDIVIDUAL AND SOCIAL SUPPORT DOMAINS ON HEALTH CARE TRANSITION READINESS OF EMERGING ADULTS WITH CONGENITAL HEART DISEASE
(East Carolina University, 2016-07-20)
Emerging adults with congenital heart disease or heart disease acquired during childhood (YACHD) require interdisciplinary services to facilitate their transition from pediatric to adult health care due to multiple components ...
Defining the Role of the C-Terminal Region of Troponin T by Analysis of a Series of Truncation Mutants
(East Carolina University, 2016-07-21)
Familial hypertrophic cardiomyopathy and other cardiovascular diseases result from mutations of any of the contractile proteins. Mutations within the actin binding regulatory complex of proteins, including tropomyosin (Tm) ...
Delineating Wastewater Contaminant Plumes from On-Site Wastewater Treatment Systems in the North Carolina Coastal Plain using Electromagnetic Induction
(East Carolina University, 2016-08-18)
In North Carolina, wastewater-derived nutrients and harmful bacteria threaten public health and reduce water quality for many surface water bodies. North Carolina uses ~ 2 million on-site wastewater treatment systems, yet ...