Browsing Dissertations by Title
Now showing items 189-208 of 291
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p53 and NGAL: dual regulatory roles in advanced prostate cancer
(East Carolina University, 2011)The development of prostate cancer from small regions of hyperplasia to invasive tumors requires genetic and epigenetic alterations of critical cellular components to aid in the development of cells more adapted for aberrant ... -
Pain Management after Cardiac Surgery
(East Carolina University, 2009)Postoperative pain relief is one of the most important concerns for patients undergoing cardiac surgery and is one of the most clinically challenging problems for nurses. It is widely recognized that postoperative pain can ... -
PARTNERSHIPS AMONG SCHOOLS AND FAITH-BASED ORGANIZATIONS : IMPACT ON STUDENT SUCCESS
(East Carolina University, 2012)The purpose of this study was to explore the perceived effect of faith-based mentorship on student academic and behavioral success by examining the impact of a specific partnership--the Uplift Mentor Program--a faith-based ... -
Paving the Way : A Biopsychosocial Survey Study of Young Adults Diagnosed with Heart Failure and Identification of Key Intervention Priorities
(East Carolina University, 2014)Introduction: Rates of heart failure have been increasingly noticed in individuals between 20 and 50 years of age, especially in Eastern North Carolina. Little is known about this subset of patients with heart failure. The ... -
THE PERCEIVED IMPACT OF THE 2006 NORTH CAROLINA STANDARDS FOR SCHOOL EXECUTIVES ON UNIVERSITY EDUCATIONAL LEADERSHIP PREPARATION PROGRAMS
(East Carolina University, 2010)Not surprisingly, the members of the Ad Hoc Committee on School Administration - a committee established by the North Carolina State Board of Education for the purpose of revising standards for principals in North Carolina ... -
PERCEPTIONS OF HOW ORGANIZATIONAL STRUCTURE IMPACTS STUDENT PERFORMANCE IN A SOUTHEASTERN NORTH CAROLINA ALTERNATIVE SCHOOL
(East Carolina University, 2015-04-29)The purpose of this study was to identify an appropriate structure to successfully serve all alternative students in an effort to increase the graduation rate and academic proficiency of the students at an alternative high ... -
PERCEPTIONS OF HOW VIRTUAL LEARNING AND SEAT TIME IMPACT STUDENT PERFORMANCE IN AN ALTERNATIVE SCHOOL
(East Carolina University, 2015-04-29)The purpose of this study is to identify an appropriate structure to successfully serve all alternative students in an effort to increase the graduation rate and academic proficiency of the students at an alternative high ... -
Perceptions of nursing as a career option held by men with experiences in military health care.
(East Carolina University, 2011)Despite notable efforts to present nursing as a viable career for men, the profession remains predominately female, and the modest changes in the numbers of men has not kept pace with the increasing demand for nursing ... -
Perceptions on cooperative learning : a case study of Kagan cooperative learning structures in the classroom
(East Carolina University, 2015-04-30)The purpose of this study was to gain insight to the perceptions of teachers and students on learning and engagement due to the implementation of Kagan cooperative learning structures. The study utilized quantitative and ... -
Perfluorooctanoic acid-induced developmental cardiotoxicity in an avian model
(East Carolina University, 2013)Perfluorooctanoic acid (PFOA) is a synthetic chemical used in polyfluormer production. It is a widespread environmental contaminant and is known to induce developmental toxicity in rodent models. As several related compounds ... -
The Physiological and Pathological Role of Mitochondrial Calcium in the Diabetic Heart
(East Carolina University, 2011)Diabetic patients are more susceptible to ischemia/reperfusion injury and cardiac dysfunction likely due alterations in mitochondrial calcium handling. The purpose of this work was to determine if redox-dependent changes ... -
A Pilot Study: The Effect of Healing Touch on Anxiety, Stress, Pain, Pain Medication Usage, and Physiological Measures in Hospitalized Sickle Cell Disease Adults Experiencing a Vaso-occlusive Pain Episode.
(East Carolina University, 2010)Sickle cell disease (SCD), a common genetic blood disorder affecting primarily African-Americans (Edwards, Scales, Loughlin, Bennett, Harris-Peterson, et al., 2005) causes a vaso-occlusive pain episode (VOPE) affecting ... -
PLANNING AND IMPLEMENTING A GLOBAL CURRICULUM : A CASE STUDY OF ONE NORTH CAROLINA ELEMENTARY SCHOOL
(East Carolina University, 2012)Today the world is more interconnected than ever (Stewart, 2012). Students in the 21st century need competent teachers who use technology as a routine way of learning, and who coach student learning that is authentic and ... -
Post-Transcriptional Regulation of mRNA Metabolism during Differentiation of 3T3-L1 Cells: Role of HuR
(East Carolina University, 2010)Our studies address early control points in the differentiation process that are necessary for expression as well as the maintenance of the adipocyte phenotype. We have focused on the post-transcriptional regulation of ... -
Potential Mechanisms for Amelioration of Type 2 Diabetes Following Bariatric Surgery
(East Carolina University, 2011)Severe obesity and Type 2 Diabetes (T2DM) are worldwide health concerns reaching epidemic proportions. Roux-en-Y gastric bypass (RYGB) has been shown to elicit a rapid and durable improvement and/or remission of T2DM in ... -
Power and Place : A Case Study Approach to Rethinking Crisis Communication
(East Carolina University, 2010)This dissertation examines a 2003 explosion at a pharmaceutical plant in Kinston, North Carolina against the framework of both crisis communication theory and critical discourse analysis theory. In the wake of the explosion, ... -
The Poxvirus A35 Protein Promotes Virulence by Regulating the Host Adaptive Immune Response
(East Carolina University, 2010)Poxviruses are large double-stranded DNA viruses with a broad host range and worldwide distribution. The most infamous poxvirus is Variola virus, the causative agent of smallpox, which caused over 500 million deaths in ... -
Pre-licensure Baccalaureate nursing students' career choice goal for a future faculty role and graduate education: adaptation and testing of social cognitive career theory.
(East Carolina University, 2011)The purpose of this study was to adapt and test the Social Cognitive Career Theory (SCCT) to (1) determine the intent of pre-licensure baccalaureate nursing students for a future faculty role and graduate education, and ... -
PREDICTING TREATMENT ADHERENCE FROM ELECTROPHYSIOLOGICAL BIOMARKERS AND INDIVIDUAL DIFFERENCES IN BEHAVORIAL ACTIVATION (BAS) AND BEHAVIORAL INHIBITION (BIS) SYSTEMS
(East Carolina University, 2014)Obstructive sleep apnea (OSA) is a common chronic sleep disorder with a demanding and complex treatment regimen. Even though continuous positive airway pressure (CPAP) is a highly effective treatment for OSA, approximately ... -
Predicting Treatment Success : Assessing Theoretically-Driven Constructs that Impact the Management of Type 2 Diabetes Mellitus Among African American Women in a Novel Peer-Delivered Small Changes Treatment Approach
(East Carolina University, 2014)Rural African American women have greater prevalence of Type 2 Diabetes Mellitus (T2DM) and poorer treatment outcomes compared to Caucasians. Some research suggests that self-efficacy, subjective norms, and locus of control ...