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Evaluation of Magnetic Resonance Imaging in Prostate Radiotherapy for Improved Treatment Outcomes
(East Carolina University, 2019-05-01)
External beam radiation therapy is among the most common modalities of curative treatment for prostate cancer and has evolved substantially with the inclusion of multimodality imaging in treatment planning. It has been ...
Racial and Religious Reconciliation: A Grounded Theory Study on African American Latter-day Saints
(East Carolina University, 2019-05-01)
Race relations between Black and White Americans continue to be tense. For African Americans, this is rooted in mistreatment by White Americans that has led to negative health outcomes. For many African Americans, religion ...
The rhetoric of climate change: Using Latour to compose a nonmodern approach to our modern climate crisis
(East Carolina University, 2019-07-23)
Climate change is the greatest threat facing humanity in the 21st century. Scientists from a variety of specialized fields, from biology and chemistry, to climatology and geology, are currently conducting research to ...
Nontraditional Pathways to the University Presidency: The Lived Experiences of Contemporary Chancellors in the University of North Carolina System
(East Carolina University, 2019-07-16)
Over the last decade, American higher education has been negatively impacted by crisis after crisis. Events such as The Great Recession of 2008 have forced institutions of higher education to do more with less. Due to these ...
Examining the Influence of Internalizing and Externalizing Maladjustment on Holland-based Vocational Interest Score Differentiation and Profile Elevation Among African American Mothers Receiving Welfare
(East Carolina University, 2019-07-22)
According to John L. Holland's (1985, 1997) theory of vocational interest types and work environments, counselors can learn whether a client is experiencing psychological maladjustment by attending to secondary constructs ...
THE MECHANISTIC TARGET OF RAPAMYCIN (mTOR) AND ITS COMPLEX 1 ASSOCIATED PROTEIN RPTOR ARE GERM CELL-AUTONOMOUSLY REQUIRED FOR SPERMATOGONIAL DEVELOPMENT & CHAPTER IV: INVESTIGATING CHANGES IN THE TESTICULAR TRANSCRIPTOME DURING THE PROSPERMATOGONIAL TRANSITION
(East Carolina University, 2019-07-26)
Stem, progenitor, and differentiating spermatogonia are formed in the neonatal mouse testis, and they provide the foundation for spermatogenesis and life-long fertility. Currently, the factors that regulate these varying ...
A SINGLE-CHAIN GMCSF-MOG TOLEROGENIC VACCINE EXPANDS MOG-SPECIFIC CD25+ FOXP3+ REGULATORY T CELLS THROUGH LOW-EFFICIENCY ANTIGEN RECOGNITION EVENTS TO INHIBIT EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
(2019-12)
Previous studies showed that tolerogenic vaccines comprised of single-chain GMCSF-neuroantigen (NAg) fusion proteins inhibited experimental autoimmune encephalomyelitis (EAE) in rodents. The studies detailed here provide ...
A Brief Intervention to Reduce Sugar Consumption on College Campuses
(East Carolina University, 2019-11-26)
Background: Research suggests that high sugar consumption is linked to a variety of health complications, including cardiovascular disease and diabetes. Previous research also suggests that adolescents and young adults ...
Development of Green Subcritical Water Separation Technology
(East Carolina University, 2019-08-19)
Theoretically speaking, water under temperature and pressure conditions below its critical point is called subcritical water. However, the term “subcritical water” normally refers to hot water up to 374 C and pressure up ...
MOLECULAR MECHANISM OF THE CYTOTOXIC AND IMMUNOSTIMULATORY ACTIVITY OF 15 DEOXY PROSTAMIDE J2: INVESTIGATION OF CHOP10 AND NFĸB SIGNALING IN COLON CANCER
(East Carolina University, 2019-08-13)
The endoplasmic reticulum (ER) stress pathway is a prominent regulator of cancer cell death and as a result, ER stress inducers are being exploited pharmacologically. Cytotoxic ER stress is typically regulated by the ...