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Post-Transcriptional Regulation of mRNA Metabolism during Differentiation of 3T3-L1 Cells: Role of HuR
(East Carolina University, 2010)
Our studies address early control points in the differentiation process that are necessary for expression as well as the maintenance of the adipocyte phenotype. We have focused on the post-transcriptional regulation of ...
[Delta]-catenin: implications in prostate cancer progression
(East Carolina University, 2014)
Prostate cancer (PCa) is the most commonly diagnosed cancer and the second most common cause of cancer death among men in the US. Due to the advances in research, the ability to detect and cure PCa has improved and led to ...
DETECTION AND DISTRIBUTION OF THE AMPHIBIAN FUNGAL DISEASE CHYTRIDIOMYCOSIS IN PERUVIAN AMPHIBIANS
(East Carolina University, 2012)
Chytridiomycosis is an amphibian disease caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd;Longcore et al. 1999). This disease has been identified by the Amphibian Conservation Action Plan as one of the main ...
Altruism, Discourse, and Blood Donation : The rhetoric of "The Gift of Life"
(East Carolina University, 2013)
The American healthcare system has since WWII regularly suffered seasonal shortages of blood donations. This dissertation examines, through the theories of activity systems, genres, frames and social groups, the discourses ...
The effects of presentation rate on semantic, syntactic, and orthographic processing and relationship to reading fluency in children
(East Carolina University, 2011)
Reading fluency is the connection between reading decoding and reading comprehension. A child becomes fluent between second and third grade (Coltheart, 1978). However, it is unknown if fluency is strictly the result of ...
Characterizing Patterns And Drivers Of Land Use/Land Cover Change Along The Atlantic Coast Barrier Beaches : Examining The Roles Of Development Pressure, Spatial Accessibility, And Policy
(East Carolina University, 2013)
Within the context of land change science coastal areas are often overlooked. Coastal areas around the world and within the U.S. represent the largest concentrations of people, development, and wealth. Natural, social, ...
Jellyfish-human interactions in North Carolina
(East Carolina University, 2013)
This dissertation investigated potential drivers of jellyfish-human interactions in North Carolina. Jellyfish populations and human use of coasts are increasing; therefore, jellyfish-human interactions are poised to become ...
Perceptions of nursing as a career option held by men with experiences in military health care.
(East Carolina University, 2011)
Despite notable efforts to present nursing as a viable career for men, the profession remains predominately female, and the modest changes in the numbers of men has not kept pace with the increasing demand for nursing ...
SKELETAL MUSCLE METABOLIC FLEXIBILITY IMPAIRMENTS IN RESPONSE TO LIPID WITH OBESITY : EFFECT OF EXERCISE TRAINING
(East Carolina University, 2012)
Obese individuals exhibit skeletal muscle metabolic inflexibility by failing to increase fat oxidation and genes linked with mitochondrial biogenesis in response to a high-fat diet (HFD) and lipid incubation in cell culture. ...
Teacher Implemented Pivotal Response Training To Improve Communication In Children With Autism Spectrum Disorders
(East Carolina University, 2011)
The primary purpose of this current investigation was to determine if a variation of Pivotal Response Training (PRT) can be effectively implemented by a preschool autism teacher in a classroom setting. The secondary purpose ...