Browsing Master's Theses by Title
Now showing items 2701-2720 of 3787
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The Role of GSK-3[beta] in MCF-7 Breast Cancer Cell Signaling and Drug Resistance
(East Carolina University, 2011)Glycogen synthase kinase- 3beta (GSK-3beta) is well documented to participate in a complex array of critical cellular processes. This versatile protein is involved in numerous signaling pathways that influence metabolism, ... -
THE ROLE OF LONG-CHAIN ACYL-COENZYME A SYNTHETASE 1 (ACSL-1) IN LIPID METABOLISM IN HUMAN SKELETAL MUSCLE PRIMARY MYOTUBES.
(East Carolina University, 2011)Obesity is considered a major health threat to the U.S. due to being a strong risk factor for developing type 2 diabetes and other metabolic diseases. The prevalence and severity of obesity is even greater among some ... -
Role of Macrophage Polarization and Apolipoprotein E in Granuloma Resolution
(East Carolina University, 2021-07-06)Sarcoidosis is a chronic disease characterized by the development and accumulation of granulomas. Through multiwall carbon nanotube (MWCNT) instillation of C57 Bl/6 (wild-type) mice, we have established a murine model that ... -
Role of Notch signaling in tumorigenesis, stemness, and epithelial to mesenchymal transtion in colorectal cancer.
(East Carolina University, 2015)Colorectal cancer is the third most commonly diagnosed cancer in both men and women in the United States. Surgical resection and combination chemotherapy are often used for treatment, but in later stages of the disease, ... -
THE ROLE OF ROYAL POWER IN THE FORMATION OF AN ANGLO-SAXON STATE, CIRCA 400-900 AD
(East Carolina University, 2012)This thesis explores the formation of a state in Anglo-Saxon England from the period of Roman withdrawal from Britain in the early fifth century to the tenth century. It argues that the key factor in the development of the ... -
The Role of Self-Efficacy and Possible Selves as Related to Personal Goals in an Employee Wellness Program
(East Carolina University, 2011)The aim of the present study was to explore the role of self-efficacy and possible selves in relation to the attainment of personal goals for participants of an employee wellness program. Also investigated was whether any ... -
The Role of Technology in the 21st Century Art Room
(East Carolina University, 2013)How are art teachers today utilizing computer technology in the classroom and what role do they feel it should serve in art education? The purpose of this study was to explore how elementary art educators in North Carolina ... -
The role of the proximal small intestine in improvements in diabetes resolution and insulin sensitivity following bariatric surgery in type 2 diabetes
(East Carolina University, 2011)Bariatric surgery is an effective, rapid, and durable treatment for obesity and type 2 diabetes mellitus (T2DM). Roux-en Y Gastric Bypass (RYGB) resolves T2DM in 80% of cases, while gastric banding (LAGB) resolves T2DM in ... -
The Role of Transcription Factors Snail and Slug in Cardiac Myofibroblasts
(East Carolina University, 2014)CCardiac fibrosis is a major facet contributing to cardiac dysfunction following a myocardial infarction. Persistent and excessive collagen deposition via cardiac myofibroblasts is the hallmark of cardiac fibrosis. Cardiac ... -
Romancing The Labor
(East Carolina University, 2013)This is a report of a creative body of work dealing with the adaptation of traditional industrial processes into contemporary sculpture. This thesis shows that admiration for labor is still present in sculpture by utilizing ... -
Rosie the Riveter and the Kitchen Soldier : Fighting the Second World War from Wilmington, North Carolina
(East Carolina University, 2015)The purpose of this thesis is to examine whether or not traditional gender norms remained standing at the conclusion of World War II in Wilmington, North Carolina. This topic would have been impossible to cover on a ... -
Roxie, Mr. Bingo, Kewl and The Gate : Street Gangs in Kinston: Participating in One City's Game of Chance to Save Itself
(East Carolina University, 2010)This project in pursuit of social and aesthetic experience involved the Kinston Community Council for the Arts, the Kinston Department of Public Safety and The Gate of Kinston (Gang Awareness Training and Education; a ... -
Rubble Along the Road: Determining the Function and Date of Occupation for a Structure on Orton Plantation
(East Carolina University, 2019-05-02)There is little known about the daily lives of the enslaved and tenant farming African Americans who lived in the Lower Cape Fear region of North Carolina during the 19th and early 20th centuries. Even on the larger ... -
Runtime Monitoring On Hard Real-Time Operating Systems
(East Carolina University, 2015)This thesis will compare and evaluate different approaches in integrating runtime monitors into processes running on a hard real-time operating system. The host system is a single board computer (SBC) with a VxWorks 653 ... -
RURALITY
(East Carolina University, 2020-06-22)Rurality is a collection of short fiction that seeks to explore the unique lives of characters in rural areas. The stories display the ways in which characters engage moral codes and challenges, while remaining in pursuit ...