Browsing Master's Theses by Title
Now showing items 624-643 of 3787
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Characterization of the GINS subunit psf1 in Drosophila Melanogaster
(East Carolina University, 2010)GINS (Go Ichi Ni San; 5,1,2,3 in Japanese) is a heterotetrameric protein complex known to be essential for the establishment of DNA replication forks and the progression of the replisome. The GINS complex is known to be ... -
Characterization of the Role of Mcm10 in DNA Replication in Drosophila melanogaster
(East Carolina University, 2013)Replication of the genome and proper formation, and packaging, of chromatin are processes essential to eukaryotic life. Maintenance of epigenetic chromatin states is essential for faithfully reproducing the transcriptional ... -
Characterization of Two Novel Mutants of DNA Polymerase Delta in Drosophila melanogaster
(East Carolina University, 2011)DNA is the genetic material for all living organisms which is constantly being unpackaged, replicated and repackaged. The replication of this genetic material involves numerous different proteins; however, DNA polymerase ... -
Characterizing Coastal Subenvironments with Modern Foraminiferal Assemblages: Bear Island and Bogue Banks, North Carolina
(East Carolina University, 2018-08-30)North Carolina's coastline consists of an extensive barrier island system, with inlets acting as pathways for the exchange of sediment and water from estuarine and open ocean environments. Reconstructing past coastal changes ... -
Characterizing Environmental and Physicochemical Conditions in Nursery Areas of River Herring in Chowan River, North Carolina
(East Carolina University, 2012)Anadromous fishes such as blueback herring Alosa aestivalis and alewife A. pseudoharengus, utilize sounds, rivers, and tributaries during spawning. Collectively known as river herring, these two ecologically important ... -
Characterizing Interactions of Thioflavin-T with Native Proteins Especially Bovine Serum Albumin
(East Carolina University, 2017-05-03)Thioflavin T is a fluorescent probe used to monitor formation of cross [beta]-sheet rich amyloid fibrils. Involvement of the amyloid fibrils is implicated in more than 50 human diseases, such as Alzheimer's, Parkinson's ... -
Characterizing the Binding of Ca2+ and Cd2+ to EF-hand Peptide V of Calbindin D28K and EF-hand Peptides III and IV of Human Cardiac Troponin C Using CD, ITC, and Fluorescence Spectroscopy
(East Carolina University, 8/5/2020)Calcium-binding EF-hand proteins are ubiquitous in the cell and are essential for many biological functions such as muscle contraction and cell signaling. Divalent cadmium, Cd²⁺, and lead, Pb²⁺ are toxic metal ions that ... -
Characterizing the Binding of Toxic and Essential Metals to EF-Hand Peptides III and IV of Human Cardiac Troponin C Using Fluorescence Spectroscopy and Isothermal Titration Calorimetry
(East Carolina University, 2023-12-05)Cadmium is one of the most toxic natural and anthropogenic metals found in our environment. Exposure to cadmium is associated with several cardiovascular conditions, neurodegenerative disorders, and cancers. Cadmium’s ... -
Characterizing the Deceased Mariners of the Swedish Warship Vasa : An Analysis of Personal Possessions Found in Association with Human Remains
(East Carolina University, 2014)On August 10, 1628, as onlookers watched in dismay, the newest and most powerful warship in Northern Europe, a symbol of the prestige and power of Sweden and Sweden's King Gustav II Adolf, heeled over and sank in Stockholm ... -
Characterizing the Expression Pattern of miR167-Regulated ZmArf3 and ZmArf30 in Maize Inflorescences
(East Carolina University, 2014)Plant growth and development depends on the activity of meristems, pools of stem cells that generate leaves and other organs. Maize (corn) produces two inflorescences, the tassel and ear, which are patterned by a series ...