Browsing Master's Theses by Title
Now showing items 921-940 of 3787
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Development of a Heart Motion Tracking System using Non-invasive Imaging Data
(East Carolina University, 2017-07-18)Cardiac motion can be monitored non-invasively for the assessment of cardiovascular function by using medical imaging systems and motion tracking algorithms. Existing tracking approaches require a priori understanding of ... -
Development of a Proton Induced X-Ray Emission (PIXE) Material Analysis System
(East Carolina University, 2019-05-07)A material analysis system using particle-induced x-ray emission (PIXE) analysis has been developed to measure trace element composition in a wide range of samples. The system was constructed in the particle accelerator ... -
Development of an Optogenetic Tool for Targeted Sensory Hair Cell Ablation in Zebrafish
(East Carolina University, 2022-04-28)Mechanosensory hair cells convert mechanical information into neuronal signals. Mutations in the genes required for hair cell function cause deafness and lead to the degeneration of sensory hair cells. Mammals are unable ... -
The Development of Confederate Ship Construction : An Archaeological and Historical Investigation of Confederate Ironclads Neuse and Jackson
(East Carolina University, 2009)Southern shipbuilding in 1861 was comparable to construction throughout the United States. Confederate ships early in the war show continuity of these traditions, but beginning in 1862, wartime stimuli created a distinct ... -
Development of Engaging Whiteboard Videos to Support Head Start Teachers’ Understanding of Evidence-based Strategies for Teaching Preschool Children (3-5 years) Science in the Context of Healthy Eating
(East Carolina University, 2023-12-07)Learning Objective: Identify Head Start teachers’ and relevant professionals’ perceptions of whiteboard videos designed to support understanding evidence-based strategies for teaching preschool children (3-5 years) science ... -
Development of NMR Methodologies to Study Site Specific Zinc-Protein Interactions
(East Carolina University, 2021-07-26)Found in all three biological domains of life and the second most abundant metal in the human body, zinc (Zn2+) is essential to various cellular processes like the metabolism of DNA and RNA, gene expression, and the ... -
DEVELOPMENT OF SMALL-MODELCULE INHIGITORS OF THE INTIATING PROTEASES, C1r AND C1s, OF THE CLASSICAL COMPLEMENT PATHWAY
(2019-12)Complement is a proteolytic cascade that upon activation plays a key effector role in the innate immune system and acts to prime the adaptive immune response. During normal homeostatic events, complement is tightly regulated ... -
Development of small-molecule inhibitors of the initiating proteases, C1r and C1s, of the classical complement pathway
(East Carolina University, 2019-12-12)Complement is a proteolytic cascade that upon activation plays a key effector role in the innate immune system and acts to prime the adaptive immune response. During normal homeostatic events, complement is tightly regulated ... -
Development of the ECU Behavioral and Lifestyle Risk Factor Assessment in Cardiology
(East Carolina University, 2021-12-08)Background: Atrial fibrillation (AF) occurs when rapid and disorganized electrical signals cause the atria in the heart to irregularly beat, not allowing blood to effectively flow from the atria to the ventricles. Over ... -
DEVELOPMENT OF UNNATURAL SUBSTRATES AND TRYPTOPHAN AMINO ACIDS TO STUDY PROTON COUPLED ELECTRON TRANSFER IN ENZYMES
(East Carolina University, 2020-12-09)Proton-coupled electron transfer plays an important role in substrate oxidation by C-H bond cleavage and long-range pathways associated with bioenergetics. This thesis is focused on the synthesis of unnatural substrates ... -
Development of Walk Tests to Estimate Aerobic Fitness in 10 to 13 Year-Old Children
(East Carolina University, 2013)Aerobic fitness is an important indicator of health for children. Estimation of aerobic fitness (VO₂[subscript]max) from field-based tests is an essential aspect of youth fitness tests. Field tests can also provide researchers ... -
Developmental Implications of Youth Sport Participation on Physical Activity and Sport Participation in Young Adulthood
(East Carolina University, 2017-12-14)This study sought to address a point of controversy within youth sports: whether young athletes should specialize early (e.g., Ericsson, Krampe & Tesch-Römer, 1993) or if it is favorable to follow the path of early ... -
Developmental lead exposure and the exacerbation of Alzheimer's pathology: an immunological analysis
(East Carolina University, 2014)Early neuroimmune dysfunction may play a driving role in the etiopathology of Alzheimer's disease (AD), stemming from the hypothesis that many late-stage adult diseases have an early-life basis. Here we explore whether ... -
Developmental pathway alterations in the stress axis of chickens exposed in ovo to an emerging environmental contaminant
(East Carolina University, 2016-12-13)Pharmaceutical and personal care products are present in the natural environment by way of the wastewater stream. They are persistent in the environment and have bioaccumulative abilities that threaten the health of both ... -
The Devonian West Falls Formation, implications of sedimentation controlled by preexisting structures, West Virginia
(East Carolina University, 2012)The Devonian (Frasnian) aged West Falls Formation in West Virginia contains gamma-ray signatures that have been interpreted to indicate sedimentation within a foreland (foredeep) basin. The West Falls Formation includes ... -
Diagnostic Accuracy of a Universal Behavior Screener for Identification of Attention Problems in First Grade
(East Carolina University, 2018-07-25)Teacher-rated inattention predicts reading outcomes, and children with both reading and elevated inattention may require special intervention. Therefore, screening of inattention seems warranted. It is examined whether ...