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Kinetic Modeling of Batch Reaction Processes
(East Carolina University, 2012)
Kinetic models have been demonstrated to be useful in on-line batch monitoring systems. The ability to monitor a reaction in real time is invaluable to the production process of industrial and pharmaceutical products. ...
Synthesis and Reactions of Novel Heteroarylzirconocene Reagents
(East Carolina University, 2012)
The cross-coupling of metallated heteroaromatic species with aryl and heteroaryl halides is a powerful and highly desirable transformation in both the synthesis of pharmaceutical compounds as well as materials development. ...
Impact of preschool handwriting without tears instruction one year following intervention
(East Carolina University, 2012)
Handwriting is a communication skill that must be taught to young students as it serves as the primary manner in which elementary school students are able to demonstrate their knowledge of academic concepts. Occupational ...
Living the Good Life? : An Analysis of Ecuador's Plan Nacional Para el Buen Vivir Development Model as an Alternative to a Neoliberal Global Framework
(East Carolina University, 2012)
In recent years, international relations scholars have focused considerable attention on the position of Latin America within the modern global political economy. A number of Latin American countries have attempted to ...
Does Dog Ownership Affect the Owners' Quality of Motivation to Engage in Physical Activity?
(East Carolina University, 2012)
Using the framework of the self-determination theory (SDT), the current study compared men and women dog owners' and non-dog owners' a) physical activity levels, b) perceived competence, autonomy, and relatedness during ...
The effectiveness of Farabloc technology with Mirror Therapy in reducing phantom limb pain in individuals with a unilateral lower extremity vascular amputation
(East Carolina University, 2012)
Objective :the objective of this study was to investigate the effectiveness of combining two interventions, Farabloc technology to eliminate electromagnetic fields and Mirror Therapy to assist in the sensory cortex ...
KINETIC MODELING OF DISSOLUTION AND CRYSTALLIZATION OF BATCH REACTIONS WITH IN SITU SPECTROSCOPIC MEASUREMENTS
(East Carolina University, 2012)
The use of Process Analytical Technology (PAT) recommended by the Food and Drug Administration (FDA) has significantly increased during the past years in the design, control and monitoring of pharmaceutical or chemical ...
IDENTIFICATION OF NOVEL CYTOTOXIC PROSTAGLANDIN METABOLITES PRODUCED IN ARACHIDONOYL ETHANOLAMIDE-TREATED TUMOREGENIC KERATINOCYTES
(East Carolina University, 2012)
Arachidonoyl ethanolamide (AEA) induces apoptosis in mouse tumorigenic keratinocytes (JWF-2 cells). Our previous data show that AEA is metabolized by COX-2 to pro-apoptotic J-series prostaglandins. COX-2 is an enzyme that ...
Thermodynamic studies of Ca²⁺ binding to human cardiac troponin C
(East Carolina University, 2012)
Human Cardiac Troponin C (HcTnC) is an EF hand protein responsible for initiating contraction of the myocardium (heart muscle). The helix-loop-helix motif, characteristic of members of the EF-hand family, allows HcTnC to ...
Adolescent Stress Induced by Family Structures and its Effect on Adult Health : A Longitudinal Assessment
(East Carolina University, 2012)
This study strives to explain the decrease in health among children and young adults in the United States in recent decades, by examining the relationship between adolescent family environments and health measures of the ...