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Child Development Knowledge and Human Factors in Toy Design : An Exploratory Study of Popular Children's Products
(East Carolina University, 2012)
Play reflects how children understand the world, and it also provides them with opportunities to learn and refine their social, emotional, motor, and problem-solving skills. Before designing a product such as a children's ...
A Protocol and Tool for Developing a Descriptive Behavioral Model
(East Carolina University, 2012)
Fuzzy rules have been used to model complex human behavior in order to develop sophisticated industrial control systems. The use of fuzzy rules to create a behavioral model provides a quantitative basis for discussing the ...
Cardiac and Mitochondrial Adaptations in Response to Aging and Doxorubicin in Rats Bred for Divergent Aerobic Capacities
(East Carolina University, 2012)
Doxorubicin (DOX) remains as one of the most widely prescribed and effective anticancer agents. A major limitation of the therapeutic effectiveness of the drug is the occurrence of irreversible, progressive, dose-dependent ...
Effects of Modified Vaccinia Virus Ankara Expressing Mesothelin and the Poxvirus Immunoregulatory A35R gene in the Treatment of Murine Pancreatic Cancer
(East Carolina University, 2012)
Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States. Pancreatic tumors over-express the protein mesothelin, and therefore, it is used as a tumor target antigen for vaccine development. ...
The Final Ambush : An Adapted Battlefield Analysis of the U-576 Attack Upon Allied Convoy KS-520 off Cape Hatteras During the Second World War
(East Carolina University, 2012)
The Battle of the Atlantic was the longest, largest, and most complex military action of the Second World War. The battle involved Allied, Axis, and neutral nations, resulting in both military and civilian casualties. At ...
"From Quiet Woods to Tide Kissed Shore" : Searching for the Colonial Port of Sunbury, Georgia
(East Carolina University, 2012)
This thesis chronicles efforts to examine a unique colonial waterfront complex in Sunbury, Georgia comprised of four distinct colonial wharf sites. To carry out an explanation of these features and Sunbury's overall ...
The foraminiferal signature of recent Gulf of Mexico hurricanes
(East Carolina University, 2012)
Down-core activities of ⁷Be, ²³⁴Th, and ²¹⁰Pb, as well as X-radiography, have indicated the existence of sediments deposited by hurricanes Ivan (2004), Katrina (2005), and Rita (2005) on the continental margin west of the ...
Comparison of Scaled vs. Ultrasound Based Musculoskeletal Models on Knee Muscle Moments During Single-Leg Squatting
(East Carolina University, 2012)
Muscles produce force, resulting in moments about a joint, causing movement of the body. Muscle forces are estimated with a Hill-type model incorporating four parameters; optimal fiber length (OFL), tendon slack length, ...
Influence of training history and contraction velocity on hamstring muscle coactivation during maximal effort knee extension
(East Carolina University, 2012)
When a muscle produces voluntary force, muscles on the opposite side of the joint, the antagonists, are also activated. While coactivation of the knee flexors during knee extension is presumed to increase joint stability ...
Beliefs, Perceptions, and Knowledge Regarding the Benefits of Nut Intake
(East Carolina University, 2012)
The objective of this study was to assess knowledge regarding the health effects and nutrient content of nuts and perceptions regarding benefits and barriers of nut intake among individuals over the age of 40 years. One ...