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Early Metabolic Differences in Alzheimer’s Disease Mouse Model and Exercise Intervention Treatment
(East Carolina University, 2017-06-22)
Alzheimer's disease (AD) is a neurodegenerative disorder that affects the central nervous system (CNS). In this study, we characterized and examined the early metabolic changes of the triple transgenic Alzheimer's disease ...
TITANIUM DIOXIDE NANOPARTICLES AFFECT THE GROWTH AND MIRNA EXPRESSION OF SWITCHGRASS (PANICUM VIRGATUM)
(East Carolina University, 2017-06-28)
Nanoparticle TiO2 is a common chemical used in paint, plastic, paper, ceramics, coated fabrics, floor coverings, printing ink, roofing granules, cosmetics, dyes and even food and drugs. As increasing usage of TiO2, it is ...
The spatial analysis of ceramic in the plow zone at Town Creek Indian Mound State Historic Site
(East Carolina University, 2017-07-05)
Ceramics are used in archaeological research to determine the spatial and temporal distributions of people in the past. Ceramics were used for cooking and serving food for households. Ceramics changed over time and can be ...
Pulmonary Artery Hemodynamics Using MRI & CFD
(East Carolina University, 2017-07-19)
Pulmonary hypertension (PH), as defined by a mean pulmonary arterial pressure (mPAP) greater than 25 mmHg, is a life-threatening chronic disorder of the pulmonary circulation which leads to right ventricle failure and if ...
Targeting Kremen1 Downregulation with RVG-9R/siRNA Complexes in the Triple-Transgenic Mouse Model of Alzheimer’s Disease
(East Carolina University, 2017-07-19)
Alzheimer's disease (AD) is a progressive disease characterized by cognitive decline and memory loss. Memory loss observed in AD results from the loss of neurons and synapses which may be caused by the disruption of the ...
THE IMPACT OF THREE DIFFERENT PHYSICAL ACTIVITY RECOMMENDATIONS ON PHYSICAL ACTIVITY
(East Carolina University, 2017-07-25)
Current physical activity guidelines encourage adults to accumulate 150 minutes of moderate intensity aerobic physical activity each week to improve health. Recommendations based on these guidelines typically focus on ...
Comparing Methodologies for Documenting Commingled and Fragmentary Human Remains
(East Carolina University, 2017-07-28)
Commingled and fragmentary human remains are a common occurrence in archaeological and forensic contexts, but only a few methods have been developed to record these complex assemblages. Conventional inventory methods, such ...
Notch 3 Affects Chemoresistance in Colorectal Cancer via DNA Base Excision Repair Enzymes
(East Carolina University, 2017-07-28)
Approximately 1.2 million cases of colorectal cancer (CRC) arise each year, and 40-50% of CRC patients will reach metastasis. The Notch pathway is known to be dysregulated in CRC, and its relationship with DNA repair ...
Automatic SQL query generation
(East Carolina University, 2017-07-19)
Automatic generation of questions for learning assessment has been an area of research interest for long. The advent of Massive Open Online Courses (MOOCs) as well as the goal of providing immediate contextualized feedback ...
Thoughts on Temporal Perception's Relativity in Grisey's Vortex Temporum and Voss's Perspectives
(East Carolina University, 2017-07-21)
This thesis centers around a comparative analysis between an instrumental work, Vortex Temporum (1995), by Gérard Grisey (1946-98), and a mixed media work by Emerson Voss (b. 1991), Perspectives (2017). This essay articulates ...