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Cleaved Caspase-3 Response to Acute Resistance Exercise in Young and Old Men and Women : Relationship to Muscle Glycogen Content and 5'-AMP-Activated Protein Kinase (AMPK) Activity
(East Carolina University, 2011)
In addition to suppressing protein synthesis and activating protein degradation in skeletal muscle and other cell types, 5'-AMP-activated protein kinase (AMPK) is known to stimulate nuclear apoptosis in non-muscle cells ...
A Comparison in Mood States of Distance and Sprint Swimmers
(East Carolina University, 2011)
The aim of the present study was to compare mood states in distance and sprint trained swimmers and observe how these moods relate to performance and change throughout the swim season. Participants from the ECU swim team ...
The Physiological and Pathological Role of Mitochondrial Calcium in the Diabetic Heart
(East Carolina University, 2011)
Diabetic patients are more susceptible to ischemia/reperfusion injury and cardiac dysfunction likely due alterations in mitochondrial calcium handling. The purpose of this work was to determine if redox-dependent changes ...
THE ROLE OF LONG-CHAIN ACYL-COENZYME A SYNTHETASE 1 (ACSL-1) IN LIPID METABOLISM IN HUMAN SKELETAL MUSCLE PRIMARY MYOTUBES.
(East Carolina University, 2011)
Obesity is considered a major health threat to the U.S. due to being a strong risk factor for developing type 2 diabetes and other metabolic diseases. The prevalence and severity of obesity is even greater among some ...
Task Specific Effects of Unilateral Eccentric and Concentric Exercise on Spinal Excitability of the Contralateral Homologous Plantar Flexors.
(East Carolina University, 2011)
It is well established that resistance training increases the size and strength of the trained muscles. It is also known that unilateral muscle contractions can produce strength gains in the non-exercised contralateral ...
The Influence of Energy Expenditure on Mitochondrial Functions, Oxidative Stress and Insulin Resistance under Metabolic Oversupply Conditions
(East Carolina University, 2011)
Mitochondrial respiratory capacity and oxidative stress have been implicated in the development of insulin resistance (IR) and type II diabetes. A causative role of mitochondrial oxidative stress in the etiology of ...
Effects of Dietary Leucine Supplementation on Muscle Mass and Markers of Protein Degradation in Overloaded Skeletal Muscles of Young Adult and Aged Rats
(East Carolina University, 2011)
The hypertrophic response to overload in fast-twitch skeletal muscle is impaired in aged humans and rats, and upregulation of protein degradation pathways are hypothesized to be a contributing factor. Muscle growth occurs ...
THE EFFECTS OF A 16 WEEK PHYSICAL ACTIVITY PROGRAM ON BONE MINERAL DENSITY IN LEAN AND OBESE PREPUBESCENT CHILDREN AGES 8-11.
(East Carolina University, 2011)
The current obesity epidemic has become a major health crisis to citizens around the United States. Obesity has been successfully linked to a plethora of different disease states including cardiovascular disease, diabetes, ...
The Effects of Aerobic Exercise Training in Children with Lean and Extremely Obese Biological Mothers
(East Carolina University, 2011)
The purpose of this study was to compare fat oxidation rates between children of lean biological mothers (CLP) (BMI[less than or equal to]28kg/m[superscript]2) and children of extremely obese biological mothers (COP) ...
Disordered Gambling: Etiology, Trajectory and Clinical Considerations
(East Carolina University, 2011-04)
Gambling-related research has advanced rapidly during the past 20 years. As a result of expanding interest toward pathological gambling (PG), stakeholders (e.g., clinicians, regulators, and policy makers) have a better ...