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Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mtor cascades which alter therapy response
(2012-09-20)
The Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades are often activated by genetic alterations in upstream signaling molecules such as receptor tyrosine kinases (RTK). Certain components of these pathways, RAS, NF1, BRAF, ...
Immune function in female B6C3F1 mice is modulated by DE-71, a commercial polybrominated diphenyl ether mixture
(2012-01-04)
Polybrominated diphenyl ethers (PBDEs) are an important class of flame-retardants that are environmentally persistent and bioaccumulative. Toxicity of these compounds has become a concern because detectable levels of PBDEs ...
Informational Odds Ratio: A Useful Measure of Epidemiologic Association in Environment Exposure Studies
(2012-04)
The informational odds ratio (IOR) measures the post-exposure odds divided by the pre-exposure odds (ie, information gained after knowing exposure status). A desirable property of an adjusted ratio estimate is collapsibility ...
Introducing the global medical community to the information presented at local scientific conferences through nephrology blogs
(2012-12-14)
An increasing number of healthcare providers author medical blogs (bloggers) to educate the public and fellow physicians. Traditionally, many bloggers have assumed that readers are most interested in information presented ...
Measures of the consumer food store environment: A systematic review of the evidence 2000-2011
(2012-08)
Description of the consumer food environment has proliferated in publication. However, there has been a lack of systematic reviews focusing on how the consumer food environment is associated with the following: (1) ...
Estimating coastal lagoon tidal flooding and repletion with multidate ASTER thermal imagery
(2012-10-18)
Coastal lagoons mix inflowing freshwater and tidal marine waters in complex spatial patterns. This project sought to detect and measure temperature and spatial variability of flood tides for a constricted coastal lagoon ...
In Vivo Blood Glucose Quantification Using Raman Spectroscopy
(2012-10-25)
We here propose a novel Raman spectroscopy method that permits the noninvasive measurement of blood glucose concentration. To reduce the effects of the strong background signals produced by surrounding tissue and to obtain ...
Factors associated with survival of veterans with gastrointestinal neuroendocrine tumors
(2012-05-27)
Background. Gastrointestinal (GI) neuroendocrine tumor (NET) incidence has been increasing; however, GI NET within the national Veterans Affairs (VA) health system has not been described. Methods. We used the VA Central ...
Landscape influences on fisher success: Adaptation strategies in closed and open access fisheries in southern Chile
(2012-03)
Determinants of fisher success in southern Chile's loco (Concholepas concholepas) fishery are examined by comparing fisher success in exclusive access territories that vary in relationship to tree-plantation development, ...