Search
Now showing items 861-870 of 991
TLR5 participates in the TLR4 receptor complex and promotes MyD88- dependent signaling in environmental lung injury
(2020-01-28)
Lung disease causes significant morbidity and mortality, and is exacerbated by environmental injury, for example through lipopolysaccharide (LPS) or ozone (O3). Toll-like receptors (TLRs) orchestrate immune responses to ...
Control of vascular smooth muscle cell growth by connexin 43
(2012-06-21)
Connexin 43 (Cx43), the principal gap junction protein in vascular smooth muscle cells (VSMCs), regulates movement of ions and other signaling molecules through gap junction intercellular communication (GJIC) and plays ...
Damage control surgery: It's evolution over the last 20 years
(2012-03-15)
In less than twenty years, what began as a concept for the treatment of exsanguinating truncal trauma patients has become the primary treatment model for numerous emergent, life threatening surgical conditions incapable ...
A system‐based intervention to reduce Black‐White disparities in the treatment of early stage lung cancer: A pragmatic trial at five cancer centers
(2019-01-11)
Background: Advances in early diagnosis and curative treatment have reduced high
mortality rates associated with non‐small cell lung cancer. However, racial disparity
in survival persists partly because Black patients ...
A Waterfront View of Coastal Hazards: Contextualizing Relationships among Geographic Exposure, Shoreline Type, and Hazard Concerns among Coastal Residents
(2019-11-26)
Coastal communities exist on the front lines of diverse natural hazards and the growing
impacts of climate change. While traditional strategies for dealing with coastal hazards have often
involved the hardening or armoring ...
Antivenom Treatment Is Associated with Fewer Patients using Opioids after Copperhead Envenomation
(2019-03-20)
Introduction
Copperhead envenomation causes local tissue destruction, leading people to seek treatment for the pain and swelling. First-line treatment for the pain is opioid medications. There is rising concern that an ...
Abnormal Involuntary Movement Scale in Tardive Dyskinesia:Minimal Clinically Important Difference
(2019-05-27)
Background
A minimal clinically important difference has not been established for the Abnormal Involuntary Movement Scale in patients with tardive dyskinesia. Valbenazine is a vesicular monoamine transporter 2 inhibitor ...
Identification of Vape Shops in Two North Carolina Counties: An Approach for States without Retailer Licensing
(2016-10-27)
Stores that sell electronic nicotine delivery systems (ENDS) as their primary product
are a new phenomenon and often termed “vape shops”. While vape shops are now regulated by
state and federal agencies, not all states ...
An Improved Algorithm to Delineate Urban Targets with Model-Based Decomposition of PolSAR Data
(2017-10-11)
In model-based decomposition algorithms using polarimetric synthetic aperture radar (PolSAR) data, urban targets are typically identified based on the existence of strong double-bounced scattering. However, urban targets ...