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Now showing items 51-60 of 85
Complementary Therapies for Significant Dysfunction from Tinnitus: Treatment Review and Potential for Integrative Medicin
(2015)
Tinnitus is a prevalent and costly chronic condition; no universally effective treatment exists. Only 20% of patients who report tinnitus actually seek treatment, and when treated, most patients commonly receive sound-based ...
Molecular Connections between Cancer Cell Metabolism and the Tumor Microenvironment
(2015)
Cancer cells preferentially utilize glycolysis, instead of oxidative phosphorylation,
for metabolism even in the presence of oxygen. This phenomenon of aerobic glycolysis,
referred to as the “Warburg effect”, commonly ...
Inhibition of Autoimmune Diabetes in NOD Mice by miRNA Therapy.
(2015)
Autoimmune destruction of the pancreatic islets in Type 1 diabetes is mediated by both increased proinflammatory (Teff) and decreased regulatory (Treg) T lymphocytes resulting in a significant decrease in the Treg:Teff ...
Murine Pancreatic Adenocarcinoma Reduces Ikaros Expression and Disrupts T Cell Homeostasis
(2015-01-28)
Background
Maintenance of T cell immune homeostasis is critical for adequate anti-tumor immunity. The transcription factor Ikaros is essential for lymphocyte development including T cells. Alterations in Ikaros expression ...
Trans-Amazon Drilling Project (TADP): origins and evolution of the forests, climate, and hydrology of the South American tropics
(2015)
This article presents the scientific rationale for an ambitious ICDP drilling project to continuously sample Late Cretaceous to modern sediment in four different sedimentary basins that transect the equatorial Amazon of ...
Mismatched anti-predator behavioral responses in predator-naïve larval anurans
(2015)
Organisms are adept at altering behaviors to balance the tradeoff between foraging and predation risk in spatially and temporally shifting predator environments. In order to optimize this tradeoff, prey need to be able to ...
Uptake of and resistance to the antibiotic berberine by individual dormant, germinating and outgrowing bacillus spores as monitored by laser tweezers raman spectroscopy
(2015-12-04)
Berberine, an alkaloid originally extracted from the plant Coptis chinensis and other herb
plants, has been used as a pharmacological substance for many years. The therapeutic
effect of berberine has been attributed to ...
Trends in Dengue Cases Imported into the United States from Pan America 2001–2012
(2015)
The objective of this study was to improve risk assessments of travel on dengue (DEN) virus (DENV) distribution. We investigated the
exposure risk of US citizens traveling to DEN-endemic Pan American countries. The number ...
WormGender – Open-Source Software for Automatic Caenorhabditis elegans Sex Ratio Measurement
(2015)
Fast and quantitative analysis of animal phenotypes is one of the major challenges of current biology. Here we report the WormGender open-source software, which is designed for
accurate quantification of sex ratio in ...
Disseminated superficial porokeratosis involving the groin and genitalia in a 72-year-old immunocompetent man
(2015-09)
The porokeratoses are a group of disorders of
abnormal epidermal keratinization resulting in the
characteristic histologic feature of the cornoid
lamella. Several clinical variants of porokeratosis
exist, which are ...