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NOTCH3 Expression Is Linked to Breast Cancer Seeding and Distant Metastasis
(2018-09-04)
Background: Development of distant metastases involves a complex multistep biological process termed the invasion-metastasis cascade, which includes dissemination of cancer cells from the primary tumor to secondary organs. ...
Nevada desert dust with heavy metals suppresses IgM antibody production
(2018-02-09)
Systemic health effects from exposure to a complex natural dust containing heavy metals from the Nellis Dunes Recreation Area (NDRA) near Las Vegas, NV, were evaluated. Several toxicological parameters were examined following ...
Preparation and characterization of flax, hemp and sisal fiber-derived mesoporous activated carbon adsorbents
(2018-02-01)
The first aim of this study was to investigate mesoporous activated carbon adsorbents from sisal, hemp, and flax fibers by cost-effective methods. Fibers were impregnated with low concentration (20 wt.%) phosphoric acid. ...
Pgrmc1 Knockout Impairs Oocyte Maturation in Zebrafish
(2018-09-24)
Recent investigations suggest progestin receptor membrane component 1 (PGRMC1) associates with and transports a wide range of molecules such as heme, cytochromes P450, steroids with 21 carbons, membrane progestin receptor ...
Quantifying the effectiveness of shoreline armoring removal on coastal biota of Puget Sound
(2018-02-23)
Shoreline armoring is prevalent around the world with unprecedented human population growth and urbanization along coastal habitats. Armoring structures, such as riprap and bulkheads, that are built to prevent beach erosion ...
Raman Characterizations of Red Blood Cells With β-Thalassemia Using Laser Tweezers Raman Spectroscopy
(2018-09-06)
This study aimed to study the differences in Raman spectra of red blood cells (RBCs) among patients with β-thalassemia and controls using laser tweezers Raman spectroscopy (LTRS) system.A total of 33 patients with β-thalassemia ...
Racial disparities in healthcare provider advice to quit smoking
(2018-03-13)
African-American/Black smokers are less likely than White smokers to be told to quit smoking by healthcare providers. This preliminary study examined the predictors of being told to quit separately by race for the first ...
Quantitative acoustic differentiation of cryptic species illustrated with King and Clapper rails
(2018-10-14)
Reliable species identification is vital for survey and monitoring programs. Recently, the development of digital technology for recording and analyzing vocalizations has assisted in acoustic surveying for cryptic, rare, ...
β-catenin nuclear translocation induced by HIF-1α overexpression leads to the radioresistance of prostate cancer
(2018-03-16)
Hypoxia-inducible factor-1α (HIF-1α) is known to play crucial roles in tumor radioresistance; however, the molecular mechanisms responsible for the promotion of tumor radioresistance by HIF-1α remain unclear. β-catenin is ...
Effects of cardiomyopathy-linked mutations K15N and R21H in tropomyosin on thin-filament regulation and pointed-end dynamics
(2018-11-14)
Missense mutations K15N and R21H in striated muscle tropomyosin are linked to dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM), respectively. Tropomyosin, together with the troponin complex, regulates ...