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Unity in defence: honeybee workers exhibit conserved molecular responses to diverse pathogens
(2017-03-02)
Background: Organisms typically face infection by diverse pathogens, and hosts are thought to have developed specific responses to each type of pathogen they encounter. The advent of transcriptomics now makes it possible ...
Weight-loss and exercise for communities with arthritis in North Carolina (we-can): design and rationale of a pragmatic, assessor-blinded, randomized controlled trial
(2017-02-22)
Background: Recently, we determined that in a rigorously monitored environment an intensive diet-induced weight loss of 10% combined with exercise was significantly more effective at reducing pain in men and women with ...
Triclosan Disrupts SKN-1/Nrf2- Mediated Oxidative Stress Response in C. elegans and Human Mesenchymal Stem Cells
(2017-10-03)
Triclosan (TCS), an antimicrobial chemical with potential endocrine-disrupting properties, may pose a risk to early embryonic development and cellular homeostasis during adulthood. Here, we show that TCS induces toxicity ...
Widespread platinum anomaly documented at theYounger Dryas onset in North American sedimentary sequences
(2017-03-09)
Previously, a large platinum (Pt) anomaly was reported in the Greenland ice sheet at the Younger Dryas
boundary (YDB) (12,800 Cal B.P.). In order to evaluate its geographic extent, fire-assay and inductively coupled plasma ...
Vegetarian Diets in the Prevention and Management of Diabetes and Its Complications
(2017-05)
Epidemiological studies have found a lower prevalence of type 2 diabetes among vegetarians compared to nonvegetarians. This reduced risk is likely a function of improved weight status, higher intake of dietary fiber, and ...
THE 2016 MODEL OF THE CLINICAL PRACTICE OF EMERGENCY MEDICINE
(2017-06)
Emergency medicine (EM) has a scientifically derived and commonly accepted description of the domain of its clinical practice. That document, “The Model of the Clinical Practice of Emergency Medicine” (EM Model), was ...
Oral microbe-host interactions: influence of β-glucans on gene expression of inflammatory cytokines and metabolome profile
(2017-03-07)
Background: The aim of this study was to evaluate the effects of β-glucan on the expression of inflammatory mediators and metabolomic profile of oral cells [keratinocytes (OBA-9) and fibroblasts (HGF-1) in a dual-chamber ...
Nearshore mixing and nutrient delivery along the western Antarctic Peninsula
(2017-10)
The surface waters of the Southern Ocean play a key role in the global climate and carbon cycles by
promoting growth of some of the world’s largest phytoplankton blooms. Several studies have emphasized the
importance of ...
Pathology Informatics Essentials for Residents: A Flexible Informatics Curriculum Linked to Accreditation Council for Graduate Medical Education Milestones
(2017-01)
Context.—Recognition of the importance of informatics to the practice of pathology has surged. Training residents in pathology informatics has been a daunting task for most residency programs in the United States because ...
Una adelfa en tierras extrañas emblemática y misoginia en la "Comedia famosa de los guanches de Tenerife y conquista de Canaria
(2017)
In his play Los guanches de Tenerife Lope de Vega resorts to one of the emblems included in his friend Hernando de Soto’s Emblemas moralizadas (1599) to dramatize the encounter between Guanches and Spaniards and to represent ...