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Essential role of proteasomes in maintaining self-renewal in neural progenitor cells
(2016-01-25)
Protein turnover and homeostasis are regulated by the proteasomal system, which is critical for
cell function and viability. Pluripotency of stem cells also relies on normal proteasomal activity that mitigates senescent ...
Failure patterns and survival outcomes in triple negative breast cancer (TNBC): a 15 year comparison of 448 non-Hispanic black and white women
(2016-06-17)
Purpose: Triple negative breast cancer (TNBC) is a distinct subtype of breast cancer with unique pathologic, molecular and clinical behavior. It occurs more frequently in young blacks and has been reported to have a shorter ...
Monopolar Detection Thresholds Predict Spatial Selectivity of Neural Excitation in Cochlear Implants: Implications for Speech Recognition
(2016)
The objectives of the study were to (1) investigate the potential of using monopolar psychophysical detection thresholds for estimating spatial selectivity of neural excitation with cochlear implants and to (2) examine the ...
Medicare Under Age 65 and Medicaid Patients Have Poorer Bowel Preparations: Implications for Recommendations for an Early Repeat Colonoscopy
(2016-05-17)
Colonoscopy is performed on patients across a broad spectrum of demographic characteristics. These characteristics may aggregate by patient insurance provider and influence
bowel preparation quality and the prevalence of ...
Pioglitazone Enhances the Beneficial Effects of Glucocorticoids in Experimental Nephrotic Syndrome
(2016-05)
Glucocorticoids are the primary therapy for nephrotic syndrome (NS), but have serious side effects and are ineffective in ~20-50% of patients. Thiazolidinediones have recently been suggested to be renoprotective, and to ...
The Effect of Casein Protein Prior to Sleep on Fat Metabolism in Obese Men
(2016-07)
We have previously shown that ingesting protein at night before sleep is either beneficial
or non-detrimental to metabolism, health, and body composition in obese women. However, the
overnight protein-induced lipolytic ...
The Role of Retinoic Acid (RA) in Spermatogonial Differentiation
(2016)
Retinoic acid (RA) directs the sequential, but distinct, programs of spermatogonial differentiation and meiotic differentiation that are both essential for the generation of functional spermatozoa. These processes are ...
The role of fishing material culture in communities’ sense of place as an added-value in management of coastal areas
(2016)
Fishing communities in many places around the world are facing significant challenges
due to new policies and environmental developments. While it is imperative to ensure sustainability
of natural resources, many policies ...
Identification of Vape Shops in Two North Carolina Counties: An Approach for States without Retailer Licensing
(2016-10-27)
Stores that sell electronic nicotine delivery systems (ENDS) as their primary product
are a new phenomenon and often termed “vape shops”. While vape shops are now regulated by
state and federal agencies, not all states ...