Browsing Health Sciences Campus by Title
Now showing items 1004-1023 of 1574
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Neuroantigen-specific, tolerogenic vaccines: GM-CSF is a fusion partner that facilitates tolerance rather than immunity to dominant self-epitopes of myelin in murine models of experimental autoimmune encephalomyelitis (EAE)
(2011)Background Vaccination strategies that elicit antigen-specific tolerance are needed as therapies for autoimmune disease. This study focused on whether cytokine-neuroantigen (NAg) fusion proteins could inhibit disease ... -
Neurogenic inflammation and sensitivity to environmental chemicals.
(East Carolina University, 1993-08)Neurogenic inflammation as a pathway distinct from antigen-driven, immune-mediated inflammation may play a pivotal role in understanding a broad class of environmental health problems resulting from chemical exposures. ... -
Neurogenic switching: a hypothesis for a mechanism for shifting the site of inflammation in allergy and chemical sensitivity.
(East Carolina University, 1995-01)Neurogenic switching is proposed as a hypothesis for a mechanism by which a stimulus at one site can lead to inflammation at a distant site. Neurogenic inflammation occurs when substance P and other neuropeptides released ... -
Neuropeptide Y analogues, compositions and methods of lowering blood pressure
(2000-06-13)Neuropeptide Y analogues, and their compositions are effective for lower blood pressure. -
Neurotransmitter Metabolism by Monoamine Oxidase in Porcine Heart Differs by Location and is Increased with Obesity/Metabolic Syndrome
(East Carolina University, 2017-05-05)Monoamine Oxidase (MAO), an outer mitochondrial enzyme, catalyzes the oxidative deamination of catecholamines and other biological amines, and in the process, produces a reactive aldehyde and H2O2. Our lab has recently ... -
Neurovascular Mechanisms of Erectile Dysfunction Following Androgen Deprivation Therapy
(East Carolina University, 2019-12-20)For nearly eight decades, androgen deprivation therapy (ADT) has been a common prostate cancer treatment. Although ADT increases the prostate cancer survival rate, urogenital side effects such as erectile dysfunction (ED) ... -
New nurse transitions: a qualitative study of perceived difficulties
(East Carolina University, 2013)The transition from student to registered nurse has proven difficult for new graduate nurses. While organizations have implemented structures and processes to support new nurse transition into practice, new nurse turnover ... -
NMR method for monitoring changes in the core of lipoprotein particles in metabolism and disease
(2017-01-14)A method is disclosed for measuring the properties of protein and lipoprotein elements in a sample. The method includes the of placing a small volume of a sample into a NMR instrument tuned to measure a particular nucleus, ... -
Nocturnal thoracoabdominal asynchrony in house dust mite-sensitive nonhuman primates
(2010)Nocturnal bronchoconstriction is a common symptom of asthma in humans, but is poorly documented in animal models. Thoracoabdominal asynchrony (TAA) is a noninvasive clinical indication of airway obstruction. In this study, ... -
Non Physician Clinicians : History from 1600's to North Carolina
(2007-08-27)Laupus Library History Collections & the Department of Bioethics & Interdisciplinary Studies sponsor the History of Medicine Presentations as an educational service for the East Carolina University community. The Library ... -
Non-stuttering biofeedback method and apparatus using daf
(2003-11-06)Methods, devices and systems treat non-stuttering speech and/or language related disorders by administering a delayed auditory feedback signal having a delay of under about 200 ms via a portable device. The DAF treatment ... -
A non-tight junction function of claudin-7—Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment
(2015-06-17)Background Claudins are a family of tight junction (TJ) membrane proteins involved in a broad spectrum of human diseases including cancer. Claudin-7 is a unique TJ membrane protein in that it has a strong basolateral ... -
Nonpharmacological Interventions for Behavior Management in Dementia
(2018-04-12)Since 2011, the Centers for Medicare and Medicaid (CMS) have been monitoring antipsychotic usage in residents with dementia in nursing homes. Increased monitoring has led to a decrease in use of these medications in ... -
Nonreceptor Tyrosine Kinase c-Yes Interacts with Occludin during Tight Junction Formation in Canine Kidney Epithelial Cells
(East Carolina University, 2002-04)Occludin is an integral membrane protein that is tyrosine phosphorylated when localized at tight junctions. When Ca2 was depleted from the culture medium, occludin tyrosine phosphorylation was diminished from Madin-Darby ... -
NORTH CAROLINA NURSES WITH SUBSTANCE USE DISORDER: A BIOPSYCHOSOCIAL EXPLORATION
(East Carolina University, 2021-04-27)Substance abuse has impacted society economically through increased healthcare costs and lost work productivity; however, the greatest impact is the loss of life. Healthcare professionals such as nurses, physicians, ... -
North Carolina's Pediatric Obesity Clinician Reference Guide and Tool Kit
(2009-07-27)This poster presents the tools developed by clinicians treating childhood obesity in North Carolina. The history of the development of these tools is outlined at the end of the accompanying abstract submission to the ... -
North Carolina's Plan to Address Obesity: Healthy Weight and Healthy Communities
(2013-02-07)This presentation describes the 2013-2020 NC Obesity Plan. Evidence based core behaviors are described as well as strategies for encouraging the adoption of those behaviors in worksites, health care and colleges and ... -
Notch 3 Affects Chemoresistance in Colorectal Cancer via DNA Base Excision Repair Enzymes
(East Carolina University, 2017-07-28)Approximately 1.2 million cases of colorectal cancer (CRC) arise each year, and 40-50% of CRC patients will reach metastasis. The Notch pathway is known to be dysregulated in CRC, and its relationship with DNA repair ... -
Notch Signaling Mediates Drug Resistance in Colorectal Cancer Cells via Effects on DNA Repair Proteins
(East Carolina University, 2016-07-25)Colorectal cancer (CRC) is the second leading cause of cancer deaths in the United States and the third most commonly diagnosed cancer in men and women. Despite tremendous progress in diagnosis, prevention, and treatment ... -
Notched Acoustic Stimulus and Tinnitus: A Treatment Intervention Using a Randomization Test Approach
(East Carolina University, 2014)Musical training has considerable effects on human brain plasticity and music listening has been investigated as a means of treating tinnitus. In a laboratory setting, tailor-made notched music has been shown to reduce ...