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Now showing items 2295-2314 of 2638
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Some Cardiomyopathy-Causing Troponin I Mutations Stabilize a Functional Intermediate Actin State
(East Carolina University, 2009-03-18)We examined four cardiomyopathy-causing mutations of troponin I that appear to disturb function by altering the distribution of thin filament states. The R193H (mouse) troponin I mutant had greater than normal actin-activated ... -
Sometimes I Think I am Losing my MIND
(2022-03-23)These slides were presented to learners through ECU's Lifelong Learning Program in Spring 2022. They provide an overview of the foods and beverages in our diets that may be hurting or helping our memory - including a review ... -
Special Concerns through an early pregnancy journey
(2016-06)Nutrition and supplementation in the woman of reproductive age can have profound and lasting effects on her child’s health. Preconception planning for all women should include advice to begin folic acid supplementation at ... -
Specific antisense oligonucleotide composition & method for treatment of disorders associated with bronchoconstriction and lung inflammation
(2000-03-21)A DNA comprises an oligonucleotide antisense to mRNA encoding an adenosine A.sub.1 or A.sub.3 receptor. The oligo is provided as a composition, various formulations, a capsule, and cartridge and in the form of a kit. The ... -
Speech in noise ability, outer hair cell function, and working memory for trained flute players.
(East Carolina University, 2015)The process of auditory speech recognition requires verbal ability, working memory, recall, and adequate auditory abilities to recognize speech. There is a well-known positive effect of musical training and experience on ... -
Speech Production Analyses: Characterizing Typical Development versus Childhood Apraxia of Speech
(East Carolina University, 2010)Childhood Apraxia of Speech (CAS) is a controversial diagnosis that is frequently based on clinical perceptions, with treatment success based on the same perceptual measures. Because additional, less abstract diagnostic ... -
SPINAL CORD REFLEXES IN A BRAIN-IRON DEFICIENT MODEL OF RESTLESS LEGS SYNDROME: ROLE OF DOPAMINE AND ADENOSINE RECEPTORS
(East Carolina University, 2021-05-04)Restless Legs Syndrome (RLS) is a sensorimotor disorder that severely disrupts sleep. RLS patients regularly present with a condition known as Brain Iron Deficiency (BID), and BID is commonly associated with altered dopamine ... -
Spleen Tyrosine Kinase (Syk) Regulates Systemic Lupus Erythematosus (SLE) T Cell Signaling
(2013)Engagement of the CD3/T cell receptor complex in systemic lupus erythematosus (SLE) T cells involves Syk rather than the zeta-associated protein. Because Syk is being considered as a therapeutic target we asked whether Syk ... -
Spontaneous Discharge Patterns in Cochlear Spiral Ganglion Cells Prior to the Onset of Hearing in Cats
(East Carolina University, 2007-10)Spontaneous neural activity has been recorded in the auditory nerve of cats as early as 2 days postnatal (P2 ), yet individual auditory neurons do not respond to ambient sound levels below 90–100 dB SPL until about P10. ... -
Spontaneous Weight Change during Chronic Hepatitis C Treatment: Association with Virologic Response Rates
(2013)Objective: We examined weight changes during chronic hepatitis C (CHC) therapy and association with virologic response. Methods: Weight changes were compared between subjects achieving rapid, early, and sustained virologic ... -
Stability of conversational language samples from children in kindergarten: the effects of time, sample length, and topic
(East Carolina University, 2010)The purpose of this study was to examine the reliability of measures from conversational language samples in the school-aged population. Two 10-minute conversational language samples were collected from 20 at-risk kindergarten ... -
Staff Education and Mothers' Postpartum Feeding Choices in a North Carolina Health Department
(2017-04-19)Maternal and pediatric benefits of breastfeeding are extensive, yet national benchmarks for postpartum breastfeeding initiation consistently go unmet nationwide. Evidence suggests that educating healthcare professionals ... -
Stair falls: caregiver’s “missed step� as a source of childhood fractures
(2014-01)Background The purpose of this study was to describe fractures sustained by children and to analyze the associated costs when a caretaker falls down stairs while holding a child. Materials and methods Between 2004 ... -
Standardized Documentation of Oral Nutrition Supplements in the Electronic Medical Record
(2019-04-22)Malnutrition is a significant problem in hospitalized patients and a major cause for poor patient outcomes including: increased length of stay, readmission rates, hospital costs, and mortality. Methods to improve the ... -
Standardized Parenteral Nutrition in the Very Low Birth Weight Infant: A Systematic Literature Review
(2015-11-11)Nutrition of the premature infant has been gaining importance as evidence emerges that early support in the critical period plays an important role in the long-term health and neurodevelopment of very low birth weight ... -
Standardized Postpartum Depression Screening of NICU Mothers
(2019-12-04)The purpose of this QI project was to determine the feasibility of instituting a standardized postpartum depression screening guideline in the NICU. A draft guideline was developed that instructed medical providers to ...