Browsing Division of Health Sciences by Title

Dare County Quality Improvement Project for the Overweight and Obese Adult Patient

King, Carol Ann; Graduate Nursing Science (2019-04-15)

Obesity is a serious disease that has tripled in prevalence since the 1980s, it affects all Americans either directly or indirectly, and attributes to several serious comorbidities and premature death. While guidelines do ...

Defending Diversity: Affirmative Action and Medical Education

DeVille, Kenneth M. (East Carolina University, 1999-08)

Affirmative action programs of all types are under attack legally and politically. Although medical schools have not been specifically targeted, their affirmative action programs, like others in higher education, are ...

Deficiency of a Sinorhizobium meliloti bacA Mutant in Alfalfa Symbiosis Correlates with Alteration of the Cell Envelope

Ferguson, Gail P.; Roop, R. Martin II; Walker, Graham C. (East Carolina University, 2002-10)

The BacA protein is essential for the long-term survival of Sinorhizobium meliloti and Brucella abortus within acidic compartments in plant and animal cells, respectively. Since both the S. meliloti and B. abortus bacA ...

Deletion of the EphA2 receptor exacerbates myocardial injury and the progression of ischemic cardiomyopathy

O'Neal, Wesley T.; Griffin, William F.; Kent, Susan D.; Faiz, Filza; Hodges, Jonathan; Vuncannon, Jackson; Virag, Jitka A. I. (2014-04)

EphrinA1-EphA-receptor signaling is protective during myocardial infarction (MI). The EphA2-receptor (EphA2-R) potentially mediates cardiomyocyte survival. To determine the role of the EphA2-R in acute non-reperfused ...

The delta-14 Mutation of Human Cardiac Troponin T Enhances ATPase Activity and Alters the Cooperative Binding of S1-ADP to Regulated Actin

Gafurov, Boris; Fredricksen, Scott; Cai, Anmei; Brenner, Bernhard; Chase, P. Bryant; Chalovich, Joseph M. (East Carolina University, 2004-12-07)

The complex of tropomyosin and troponin binds to actin and inhibits activation of myosin ATPase activity and force production of striated muscles at low free Ca2+ concentrations. Ca2+ stimulates ATP activity, and at ...

Delta-Catenin Induced Dendritic Morphogenesis: An Essential Role of p190RhoGEF Interaction through Akt1 Mediated Phosphorylation

Kim, Hangun; Han, Jeong-Ran; Park, Jaejun; Oh, Minsoo; James, Sarah E.; Chang, Sunghoe; Lu, Qun; Lee, Kwang Youl; Ki, Hyunkyoung; Song, Woo-Joo; Kwonseop, Kim (East Carolina University, 2008-01-11)

delta-Catenin was first identified through its interaction with Presenilin-1 and has been implicated in the regulation of dendrogenesis and cognitive function. However, the molecular mechanisms by which delta-catenin ...

delta-Catenin promotes prostate cancer cell growth and progression by altering cell cycle and survival gene profiles

Zeng, Yan; Abdallah, Agustin; Lu, Jian-Ping; Wang, Tao; Chen, Yan-Hua; Terrian, David M.; Kim, Kwonseop; Lu, Qun (East Carolina University, 2009-03-10)

Background: delta-Catenin is a unique member of delta-catenin/armadillo domain superfamily proteins and its primary expression is restricted to the brain. However, delta-catenin is upregulated in human prostatic adenocarcinomas, ...

[Delta]-catenin: implications in prostate cancer progression

Nopparat, Jongdee (East Carolina University, 2014)

Prostate cancer (PCa) is the most commonly diagnosed cancer and the second most common cause of cancer death among men in the US. Due to the advances in research, the ability to detect and cure PCa has improved and led to ...

Democedes of Corton and the State of Pre-Hippocratic Medicine in Ancient Greece

Papalas, Anthony J. (2008-11-03)

Laupus Library History Collections & the Department of Bioethics & Interdisciplinary Studies sponsor the History of Medicine Presentations as an educational service for the East Carolina University community. The Library ...

Deoxyguanosine-resistant Leukemia L1210 Cells: Loss of Specific Deoxyribonecleoside Kinase Activity

Cory, Ann H.; Shibley, Ivan A.; Chalovich, Joseph M.; Cory, Joseph G. (East Carolina University, 1993-01-05)

A mouse leukemia L1210 cell line was selected for resistance to deoxyguanosine. The deoxyguanosine-resistant cells (dGuo-R) were 126-fold less sensitive to deoxyguanosine than the wild-type cells. The IC50 values for araC ...

A depauperate immune repertoire precedes evolution of sociality in bees

Barribeau, Seth M.; Sadd, Ben M.; du Plessis, Louis; Brown, Mark J.; Buechel, Severine D.; Cappelle, Kaat; Carolan, James C.; Christiaens, Olivier; Colgan, Thomas J.; Erler, Silvio; Evans, Jay; Helbing, Sophie; Karaus, Elke; Lattorff, H. M. G.; Marxer, Monika; Meeus, Ivan; Näpflin, Kathrin; Niu, Jinzhi; Schmid-Hempel, Regula; Smagghe, Guy; Waterhouse, Robert M.; Yu, Na; Zdobnov, Evgeny M.; Schmid-Hempel, Paul (2015-04-24)

Background Sociality has many rewards, but can also be dangerous, as high population density and low genetic diversity, common in social insects, is ideal for parasite transmission. Despite this risk, honeybees and other ...

Describing the Relationship Between Psychosocial Distress and Extent of Criminal Justice System Involvement for Men and Women in a Sober Living Environment

Coleman, Samantha M (East Carolina University, 2016-04-14)

Symptoms of mental health and substance use disorders are prevalent for individuals involved in the criminal justice system and are associated with both costs to society and the individual. The purpose of this study was ...

A descriptive exploratory study on how nurse educators use digital stories in the classroom

Schwartz, Melissa R. (East Carolina University, 2014)

This study examines the experiences of 12 nurse educators using digital stories in undergraduate nursing courses. Two issues were explored: 1) How and for what purpose are nurse educators incorporating digital stories in ...

Determining New Directions for a Rural Academic Library/ Outreach Services Program: What was learned from a 2006 needs assessment of healthcare providers.

Ketterman, Elizabeth; Simpson, Susan (2006-10-15)

A needs assessment of healthcare providers in the rural, 23-country Eastern AHEC region results in changes to the delivery of library and information services.

Developing an agenda for research about policies to improve access to healthy foods in rural communities: a concept mapping study

Johnson, Donna B.; Quinn, Emilee; Sitaker, Marilyn; Ammerman, Alice S.; Byker, Carmen; Dean, Wesley; Fleischhacker, Sheila; Kolodinsky, Jane; Pinard, Courtney; Jilcott Pitts, Stephanie Bell; Sharkey, Joseph (2014)

Background Policies that improve access to healthy, affordable foods may improve population health and reduce health disparities. In the United States most food access policy research focuses on urban communities even ...