Browsing Health Sciences Campus by Author "Abdel-Rahman, Abdel A."
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Aldehyde Dehydrogenase Inhibition Ameliorates Cardiac Dysfunction and Exacerbates Hypotension Caused by Alcohol in Female Rats
Abdel-Rahman, Abdel A. (2020-11-24) -
Brain stem adenosine receptors modulate centrally mediated hypotensive responses in conscious rats: A review
Nassar, Noha N.; Abdel-Rahman, Abdel A. (2014-12)Abbreviations: A2A, adenosine subtype A2A receptor; A1, adenosine subtype A1 receptor; ABC, avidin biotin complex; ABD rat, aortic barodenervated rat; α2 AR, alpha 2 adrenergic receptor; αMNE, alpha methyl norepinephrine; ... -
Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A review
Ibrahim, Badr M.; Abdel-Rahman, Abdel A. (2013-04)Cannabinoids elicit complex hemodynamic responses in experimental animals that involve both peripheral and central sites. Centrally administered cannabinoids have been shown to predominantly cause pressor response. However, ... -
Central GPR109A activation Mediates Glutamate-Dependent Pressor Response in Conscious Rats
Abdel-Rahman, Abdel A. (2016-11-30) -
Central GPR109A Mediates Neuronal Oxidative Stress and Pressor Response in Conscious Rats
Rezq, Samar (East Carolina University, 2016-05-03)The primary goal of this study was to characterize the role of GPR109A in the rostral ventrolateral medulla (RVLM) in blood pressure (BP) regulation and to elucidate the mechanisms involved in the hypertensive response ... -
Chronic ethanol attenuates centrally-mediated hypotension elicited via alpha-2-adrenergic, but not I1-imidazoline, receptor activation in female rats
El-Mas, Mahmoud M.; Abdel-Rahman, Abdel A. (East Carolina University, 2009-01-16)Aims—This study dealt with the effect of chronic ethanol administration on hemodynamic responses elicited by α2-adrenergic (α-methyldopa) or I1-imidazoline (rilmenidine) receptor activation in telemetered female rats. Main ... -
Combined Catalase and ADH Inhibition Ameliorates Ethanol-Induced Myocardial Dysfunction Despite Causing Oxidative Stress in Conscious Female Rats
Abdel-Rahman, Abdel A. (2017-07-25) -
Cystathionine-γ Lyase-Derived Hydrogen Sulfide Mediates the Cardiovascular Protective Effects of Moxonidine in Diabetic Rats
Abdel-Rahman, Abdel A. (2016-07-01) -
Disrupted Adiponectin-Connexin43 Signaling Underlies Exacerbated Myocardial Dysfunction in Diabetic Female Rats
Leffler, Korin Eileen (East Carolina University, 2019-04-25)The 2015 American Heart Association scientific statement has advocated for sex- specific research to understand the paradoxically higher sensitivity of women to type 2 diabetes mellitus (T2DM)-associated cardiovascular ... -
The Effect of Chronic Activation of the Novel Endocannabinoid Receptor GPR18 on Myocardial Function and Blood Pressure in Conscious Rats
Abdel-Rahman, Abdel A. (2017-01-01) -
Effect of testosterone replacement or duration of castration on baroreflex bradycardia in conscious rats
Ward, Gregg R.; Abdel-Rahman, Abdel A. (East Carolina University, 2005-03-30)Background: In this study, we tested the hypothesis that 17β-estradiol contributes to testosterone-mediated restoration of baroreflex-mediated bradycardia in short-term (3 weeks) castrated rats. Further, a reported increase ... -
Epidemiology of Alcohol Use in the General Population of Togo
Abdel-Rahman, Abdel A. (2015-08-01) -
Estrogen Modulation of the Ethanol-Evoked Myocardial Oxidative Stress and Dysfunction via DAPK3/Akt/ERK Activation in Male Rats
Abdel-Rahman, Abdel A. (2015-09-01) -
Estrogen Receptor ERα Plays a Major Role in Ethanol-Evoked Myocardial Oxidative Stress and Dysfunction in Conscious Female Rats
Abdel-Rahman, Abdel A. (2016-02-01) -
Estrogen Receptor α Activation Enhances its Cell Surface Localization and Improves Myocardial Redox Status in Ovariectomized Rats
Abdel-Rahman, Abdel A. (2017-08-01) -
Estrogen Receptors α and β Play Major Roles in Ethanol-Evoked Myocardial Oxidative Stress and Dysfunction in Conscious Ovariectomized Rats
Abdel-Rahman, Abdel A. (2017-12-29) -
Estrogen-dependent enhancement of NO production in the nucleus tractus solitarius contributes to ethanol-induced hypotension in conscious female rats
Li, Guichu; Abdel-Rahman, Abdel A. (East Carolina University, 2009-02)Background- Our previous pharmacological and cellular studies showed that peripheral (cardiac and vascular) NOS-derived NO is implicated in the estrogen-dependent hypotensive action of ethanol in female rats. The objective ... -
Estrogen-Dependent Hypersensitivity to Diabetes-Evoked Cardiac Autonomic Dysregulation: Role of Hypothalamic Neuroinflammation
Abdel-Rahman, Abdel A. (2020-06-01) -
Hypothalamic Kinin B1 Receptor Mediates Orexin System Hyperactivity in Neurogenic Hypertension
Parekh, Rohan Umesh; White, Acacia; Lefer, Korin E.; Abdel-Rahman, Abdel A.; Sriramula, Srinivas; Biancardi, Vinicia C.; Eells, Jeffrey B. (2021) -
Inhibition of Nischarin Expression Attenuates Rilmenidine-Evoked Hypotension and Phosphorylated Extracellular Signal-Regulated Kinase 1/2 Production in the Rostral Ventrolateral Medulla of Rats
Zhang, Jian; Abdel-Rahman, Abdel A. (East Carolina University, 2008-01)Imidazoline (I1)-evoked hypotension is linked to enhanced phosphorylated extracellular signalregulated kinase (pERK)1/2 production in the rostral ventrolateral medulla (RVLM). Recent cell culture findings suggest that ...