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Brain-derived neurotrophic factor and neurotrophin receptors modulate glutamate-induced phase shifts of the suprachiasmatic nucleus
(East Carolina University, 2006-08)
Light information reaches the suprachiasmatic nucleus (SCN) through a subpopulation of retinal ganglion cells. Previous work raised the possibility that brain-derived neurotrophic factor (BDNF) and its high-affinity ...
Investigations Of The Impact Of Altered Auditory Feedback In-The-Ear Devices On The Speech Of People Who Stutter: One-Year Follow-Up
(East Carolina University, 2006)
Purpose: This study examined objective and subjective measures of the effect of a self-contained ear-level device delivering altered auditory feedback (AAF) for those who stutter 12 months following initial fitting with ...
Predifferentiated Embryonic Stem Cells Prevent Chronic Pain Behaviors and Restore Sensory Function Following Spinal Cord Injury in Mice
(East Carolina University, 2006)
Embryonic stem (ES) cells have been investigated in repair of the CNS following neuronal injury and disease; however, the efficacy of these cells in treatment of postinjury pain is far from clear. In this study, we evaluated ...
RecA and RadA Proteins of Brucella abortus Do Not Perform Overlapping Protective DNA Repair Functions following Oxidative Burst
(East Carolina University, 2006-07)
Very little is known about the role of DNA repair networks in Brucella abortus and its role in pathogenesis. We investigated the roles of RecA protein, DNA repair, and SOS regulation in B. abortus. While recA mutants in ...
Raman spectroscopy: the gateway into tomorrow's virology
(East Carolina University, 2006-06-28)
In the molecular world, researchers act as detectives working hard to unravel the mysteries surrounding cells. One of the researchers' greatest tools in this endeavor has been Raman spectroscopy. Raman spectroscopy is a ...
Identification, cloning and functional characterization of novel beta-defensins in the rat (Rattus norvegicus)
(East Carolina University, 2006-02-04)
Background
beta-defensins are small cationic peptides that exhibit broad spectrum antimicrobial properties. The majority of beta-defensins identified in humans are predominantly expressed in the male reproductive tract ...
Healthy Hospital Food Environment: the PCMH Story.
(2006)
This paper describes Pitt Memorial Hospital's response to the call to become a healthy worksite. It describes the hospital's effots to partner in the North Carolina Plan to Prevent Overweight and Obesity and Related Chronic ...
Insights Into Elevated Distortion Product Otoacoustic Emissions In Sickle Cell Disease: Comparisons of Hydroxyurea-treated and Non-treated Young Children
(East Carolina University, 2006)
Distortion product otoacoustic emissions (DPOAEs) were examined in 15 normal- hearing African-American children between the ages of 6 and 14 years with homozygous sickle cell disease (SCD), who were on a regimen of hydroxyurea ...
Auditory Temporal Resolution In Normal Hearing Preschool Children Revealed by Word Recognition In Continuous And Interrupted Noise
(East Carolina University, 2006)
The purpose of this study was to examine temporal resolution in normal hearing pre-school children. Word recognition was evaluated in quiet and in spectrally identical continuous and interrupted noise at signal-to-noise ...
Leadership Boot Camp
(East Carolina University, 2006)