Browsing Brody School of Medicine by Title
Now showing items 1304-1323 of 1483
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Spleen Tyrosine Kinase (Syk) Regulates Systemic Lupus Erythematosus (SLE) T Cell Signaling
(2013)Engagement of the CD3/T cell receptor complex in systemic lupus erythematosus (SLE) T cells involves Syk rather than the zeta-associated protein. Because Syk is being considered as a therapeutic target we asked whether Syk ... -
Spontaneous Weight Change during Chronic Hepatitis C Treatment: Association with Virologic Response Rates
(2013)Objective: We examined weight changes during chronic hepatitis C (CHC) therapy and association with virologic response. Methods: Weight changes were compared between subjects achieving rapid, early, and sustained virologic ... -
Statins induce lethal effects in acute myeloblastic lymphoma cells within 72 hours
(East Carolina University, 2008-02)HMG-CoA Reductase inhibitors (statins) induce apoptosis in acute myeloid leukemia (AML) cells in vitro; however, the concentrations associated with cell death in AML cells are higher than those clinically tolerated during ... -
Stay Healthy with holiday advice
(2020-12-02)This is a weekly Q and A newspaper column under the byline of Dr. Kathy Kolasa. Today's column is navigating how to stay healthy throughout the holiday season. -
Steer children toward water and milk consumption
(2024-04-03) -
Stimulation of glucose uptake by insulin-like growth factor II in human muscle is not mediated by the insulin-like growth factor II/mannose 6-phosphate receptor.
(East Carolina University, 1994-06-15)Although the growth-promoting effects of insulin-like growth factor II (IGF-II) have been intensively studied, the acute actions of this hormone on glucose metabolism have been less well evaluated, especially in skeletal ... -
Stop wasting food and money by safely storing leftovers
(2022-01-05)This is a weekly Q and A newspaper column under the byline of Dr. Kathy Kolasa. Today's column is about how to make good use of leftovers without getting food poisoning. -
Strain-Dependent Variation in Acute Ischemic Muscle Injury
(2918-05-01) -
Stress and burnout in nutrition and dietetics
(2018-03)Literature from across multiple health professions points to a budding crisis where current and future health professionals are experiencing stress and burnout at an alarming rate that threatens the vitality of our healthcare ... -
Structural and functional analysis of the Vaccinia virus O1 virulence protein
(East Carolina University, 2017-07-26)Poxviruses are double-stranded DNA viruses capable of causing disfiguring and deadly disease in a wide range of hosts, from insects to mammals. Orthopoxviruses (OPXV) encode many proteins that are not essential for viral ... -
STRUCTURE-FUNCTION ANALYSIS OF A FAMILY OF BORRELIAL C1r INHIBITORS FROM LYME DISEASE AND RELAPSING FEVER SPIROCHETES
(East Carolina University, 2023-06-01)The complement system is an ancient part of the innate immune system consisting of fluid-phase proteins that contribute to inflammation, homeostasis, and pathogen clearance. A group of vector-borne spirochetal pathogens ... -
Subcellular fractionation method to study endosomal trafficking of Kaposi’s sarcoma-associated herpesvirus
(2016-01)Background Virus entry involves multiple steps and is a highly orchestrated process on which successful infection collectively depends. Entry processes are commonly analyzed by monitoring internalized virus particles ... -
Subcellular fractionation method to study endosomal trafficking of Kaposi’s sarcoma-associated herpesvirus
(2016-01-15)Background: Virus entry involves multiple steps and is a highly orchestrated process on which successful infection collectively depends. Entry processes are commonly analyzed by monitoring internalized virus particles ...