Search
Now showing items 1-10 of 78
Disruption of mitochondrial fitness in human preadipocytes by fatty acids
(East Carolina University, 2013)
Adipose tissue lies at the core of energy metabolism, by not only releasing and taking up fatty acids (FA) according to the individuals overall surplus or deficit of energy, but also signaling other tissues to regulate ...
The role of PPARγ in carbon nanotube-elicited granulomatous lung inflammation
(2013)
BACKGROUND:
Although granulomatous inflammation is a central feature of many disease processes, cellular mechanisms of granuloma formation and persistence are poorly understood. Carbon nanoparticles, which can be products ...
Spontaneous Weight Change during Chronic Hepatitis C Treatment: Association with Virologic Response Rates
(2013)
Objective: We examined weight changes during chronic hepatitis C (CHC) therapy and association with virologic response.
Methods: Weight changes were compared between subjects achieving rapid, early, and sustained virologic ...
Transplant Coordinators' Perceived Impact of Availability of Multiple Generic Immunosuppression Therapies on Patients, Workload, and Posttransplant Maintenance Therapy
(2013)
Background. No studies have evaluated the impact of multiple generic immunosuppression medications on transplant coordinators (TCs) and patients. Methods. A cross-sectional, multicenter online survey of TCs managing ...
Postpartum spontaneous dissection of the first obtuse marginal branch of the left circumflex coronary artery causing acute coronary syndrome: a case report and literature review
(2013)
Spontaneous coronary artery dissection (SCAD) is a very rare cause of acute coronary syndromes in young otherwise healthy patients with a striking predilection for the female gender. The pathological mechanism has not been ...
Using TIRF microscopy to analyze stimulated and basal state B-cell MHC II clustering in response to ageing and dietary fish oil
(East Carolina University, 2013)
This research focused on developing an efficient TIRF microscopy approach to evaluate membrane protein organization. More specifically, the data demonstrate that TIRF microscopy can detect changes in ex vivo B-cell MHC II ...
The heart healthy lenoir project-an intervention to reduce disparities in hypertension control: study protocol
(2013)
Background
Racial disparities in blood pressure control are well established; however the impact of low health literacy (LHL) on blood pressure has garnered less attention. Office based interventions that are created with ...
Perfluorooctanoic acid-induced developmental cardiotoxicity in an avian model
(East Carolina University, 2013)
Perfluorooctanoic acid (PFOA) is a synthetic chemical used in polyfluormer production. It is a widespread environmental contaminant and is known to induce developmental toxicity in rodent models. As several related compounds ...