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Cardiac tamponade and pericardial disorders in connective tissue diseases: case report and literature review.
(East Carolina University, 1994-02)
Pericardial disorders occurring in connective tissue diseases are not uncommon and may present as acute or chronic pericarditis with or without an effusion. In many instances, a diagnosis of pericardial involvement is not ...
The role of mediators of neuronal plasticity in the circadian regulation of suprachiasmatic nucleus by light
(East Carolina University, 2009)
Circadian rhythms are highly conserved physiological functions that are present in almost all living organisms. In mammals, circadian rhythms are synchronized to the environmental light:dark cycle by daily adjustments in ...
Multiple Kinase Involvement in the Regulation of Vascular Growth
(New York: InTech Open Access Publishers, 2012-06)
The initial discovery of protein phosphorylation as a regulatory mechanism for the control of glycogen metabolism has led to intense interest of protein phosphorylation in regulating protein function (Cohen et al., 2001). ...
Th1 Adjuvant N-Acetyl-d-Glucosamine Polymer Up-Regulates Th1 Immunity but Down-Regulates Th2 Immunity against a Mycobacterial Protein (MPB-59) in Interleukin-10-Knockout and Wild-Type Mice
(East Carolina University, 2001-10)
Treatment of mice with heat-killed (HK) Mycobacterium bovis BCG or 1- to 10-μm chitin particles (nonantigenic N-acetyl-d-glucosamine polymers) is known to induce innate immune responses, including gamma interferon (IFN-γ) ...
Perceptions of the Community Food Environment and Related Influences on Food Choice Among Midlife Women Residing in Rural and Urban Areas: A Qualitative Analysis
(East Carolina University, 2009)
Introduction—Qualitative research on food choice has rarely focused on individuals’ perceptions of the community food environment. Women remain gatekeepers of the family diet and food purchasing. Therefore we assessed ...
Solubility and Bioactivity of the Pseudomonas Quinolone Signal Are Increased by a Pseudomonas aeruginosa-Produced Surfactant
(East Carolina University, 2005-02)
Pseudomonas aeruginosa is a gram-negative bacterium that causes serious infections in immunocompromised individuals and cystic fibrosis patients. This opportunistic pathogen controls many of its virulence factors and ...
Inhibition by rapamycin of ornithine decarboxylase and epithelial cell proliferation in intestinal IEC-6 cells in culture
(East Carolina University, 1997-02)
1 Induction of the enzyme ornithine decarboxylase (ODC) appears to be controlled primarily at the
level of ODC mRNA translation. The immunosuppressant drug, rapamycin, blocked the induction of
ODC in response to serum ...
Allopurinol improves myocardial reperfusion injury in a xanthine oxidase-free model
(East Carolina University, 1995-07)
The ability of allopurinol to protect against reperfusion injury in the heart has usually been attributed to its xanthine oxidase (XO)- inhibiting properties. Human myocardium how- ever, has exhibited low levels of XO ...
Mast cells and the IL-33/ST2 axis are essential determinants of carbon nanotube toxicity
(East Carolina University, 2012)
The rise of nanomaterial use in a variety of applications, including biomedical imaging and drug delivery, has led to concern about the potentially hazardous impacts on human health. Mast cells are critical for innate and ...
Effect of gender on auditory brainstem response latencies and thresholds to air-and bone-conducted clicks in newborn infants
(East Carolina University, 2001)
Objective: An examination of gender differences in auditory brainstem response (ABR) wave V latencies and thresholds to air-and bone- conducted clicks was undertaken with newborn infants. Design: Two hundred and two full-term ...