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Acidosis Activates Endoplasmic Reticulum Stress Pathways through GPR4 in Human Vascular Endothelial Cells
(2017-01-27)
Acidosis commonly exists in the tissue microenvironment of various pathophysiological conditions such as tumors, inflammation, ischemia, metabolic disease, and respiratory disease. For instance, the tumor microenvironment ...
The Bee Microbiome: Impact on Bee Health and Model for Evolution and Ecology of Host-Microbe Interactions
(2016)
As pollinators, bees are cornerstones for terrestrial ecosystem stability and key components in agricultural productivity. All animals, including bees, are associated with a diverse community of microbes, commonly referred ...
A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women
(2017-03-02)
SNP rs7903146 in the Wnt pathway’s TCF7L2 gene is the variant most significantly associ- ated with type 2 diabetes to date, with associations observed across diverse populations. We sought to determine whether variants in ...
What factors influence older people’s intention to enrol in nursing homes? A cross-sectional observational study in Shanghai, China
(2018-09-05)
Objectives Given the increasing need of long-term care and the low occupancy rate of nursing homes in Shanghai, this study attempts to explore what factors influence older people’s intention to enrol in nursing homes.
Design ...
“Their Packaging Has Always Been Like a Power”: A Qualitative Study of U.S. Smokers’ Perceptions of Cigarette Pack Visual Design Features to Inform Product Regulation
(2017-10-17)
Cigarette packaging matters to consumer behavior. However, it is less clear which changes to packaging design would be salient for adult smokers. Such information is critically important to regulators in the United States ...
A Proposed Set of Metrics to Reduce Patient Safety Risk From Within the Anatomic Pathology Laboratory
(2017-05)
Background: Anatomic pathology laboratory workflow consists of 3 major specimen handling processes. Among the workflow are preanalytic, analytic, and postanalytic phases that contain multistep subprocesses with great impact ...
a single-institution analysis of 126 Patients Treated with stereotactic radiosurgery for Brain Metastases
(2017-05-12)
Background: The objective of this study was to report our institutional experience with Gamma Knife® Radiosurgery (GKRS) in the treatment of patients with brain metastases.
Methods: Retrospectively collected demographic ...
Single-institution comparative study on the outcomes of salvage cryotherapy versus salvage robotic prostatectomy for radio-resistant prostate cancer
(2015)
Background
Although primary treatment of localized prostate cancer provides excellent oncologic control, some men who chose radiotherapy experience a recurrence of disease. There is no consensus on the most appropriate ...
Sclerosing Mesenteritis: A Rare Cause of Small Bowel Obstruction
(2016)
Sclerosing mesenteritis falls within a spectrum of primary idiopathic inflammatory and fibrotic processes that affect the mesentery. The exact etiology has not been determined, although
the following associations have ...
High-intensity exercise to promote accelerated improvements in cardiorespiratory fitness (HI-PACE): study protocol for a randomized controlled trial
(2019-08-08)
Background:
African Americans have a disproportionate prevalence and incidence of type 2 diabetes compared with Caucasians. Recent evidence indicates that low cardiorespiratory fitness (CRF) level, an independent risk ...