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Resveratrol inhibits KSHV reactivation by lowering the levels of cellular Egr-1
(2012-03-12)
In the field of herpesvirus research, the exact molecular mechanism by which such viruses reactivate from latency remains elusive. Kaposi's sarcoma-associated herpesvirus (KSHV) primarily exists in a latent state, while ...
Time course of altered sensitivity to inhibitory and excitatory agonist responses in the longitudinal muscle-myenteric plexus and analgesia in the guinea pig after chronic morphine treatment
(2012-01-10)
Tolerance that develops after chronic morphine exposure has been proposed to be an adaptive response that develops and decays over a defined time course. The present study examined the development of tolerance to the acute ...
Applying the Socio-Ecological Model to barriers to implementation of ACL injury prevention programs: A systematic review
(2017-09-28)
Background: Preventing anterior cruciate ligament (ACL) injuries is important to avoid long-term adverse health consequences. Identifying barriers to implementation of these prevention programs is crucial to reducing the ...
Tweeting the meeting: An in-depth analysis of Twitter activity at kidney week 2011
(2012-07-05)
In recent years, the American Society of Nephrology (ASN) has increased its efforts to use its annual conference to inform and educate the public about kidney disease. Social media, including Twitter, has been one method ...
The impact of mild stroke on participation in physical fitness activities
(2012)
Objective. To compare participation in moderate to high intensity physical activities in persons before and after a mild stroke. Methods. We used data from the Cognitive Rehabilitation and Research Group to examine changes ...
Association Between Health Literacy, Electronic Health Literacy, Disease-Specific Knowledge, and Health-Related Quality of Life Among Adults With Chronic Obstructive Pulmonary Disease: Cross-Sectional Study
(2019-06-06)
Background: Despite the relatively high prevalence of low health literacy among individuals living with chronic obstructive pulmonary disease (COPD), limited empirical attention has been paid to the cognitive and health ...
Conspecific brood parasitism in the tropics: An experimental investigation of host responses in common moorhens and American purple gallinules
(2011-08-03)
Species occupying a broad latitudinal range may show greater phenotypic plasticity in behavior than species with smaller ranges or more specific habitat requirements. This study investigates for the first time the occurrence ...
Synchronized Beta-Band Oscillations in a Model of the Globus Pallidus - Subthalamic Nucleus Network under External Input
(2016)
Hypokinetic symptoms of Parkinson’s disease are usually associated with the excessively strong oscillations and synchrony in the beta frequency band. The origin of this synchronized oscillatory dynamics is being debated. ...
Subcellular fractionation method to study endosomal trafficking of Kaposis sarcoma-associated herpesvirus
(2016)
Background: Virus entry involves multiple steps and is a highly orchestrated process on which successful infection
collectively depends. Entry processes are commonly analyzed by monitoring internalized virus particles via ...
Cutaneous adverse reactions in B-RAF positive metastatic melanoma following sequential treatment with B-RAF/MEK inhibitors and immune checkpoint blockade or vice versa. A single-institutional case-series
(2018-12-16)
Background
With the advent of immune-checkpoint inhibitors and targeted treatments (TT), there have been unprecedented response rates and survival in advanced melanoma, but the optimal sequencing of these two treatments ...