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An Emerging Natural History in the Development, Mechanisms and Worldwide Prevalence of Major Mental Disorders
(2016-12-30)
Conciliating recent findings from molecular genetics, evolutionary biology, and clinical observations together point to new understandings regarding the mechanism, development and the persistent worldwide prevalence of ...
Airway observations during upper endoscopy predicting obstructive sleep apnea
(2016-06-10)
Background This pilot study examined airway characteristics during upper endoscopy to determine who is at high risk for obstructive sleep apnea.
Methods Patients undergoing routine upper endoscopy were divided into 2 ...
“Moving Toward Healthy”: Insights Into Food Choices of Mothers in Residential Recovery
(2016-11)
This study utilized participatory and potentially empowering qualitative research methods of photo-elicitation and face- to-face interviews to investigate food choices of mothers living with their children in a residential ...
Assessment of Occupational Noise Exposure among Groundskeepers in North Carolina Public Universities
(2016-05-12)
Groundskeepers may have increased risk to noise-induced hearing loss due to the performance of excessively noisy tasks. This study assessed the exposure of groundskeepers to noise in multiple universities and determined ...
A Micro-Thermal Sensor for Focal Therapy Applications
(2016-02-26)
There is an urgent need for sensors deployed during focal therapies to inform treatment planning and in vivo monitoring in thin tissues. Specifically, the measurement of thermal properties, cooling surface contact, tissue ...
A systematic mRNA control mechanism for germline stem cell homeostasis and cell fate specification
(2016-02)
Germline stem cells (GSCs) are the best understood adult stem cell types in the nematode Caenorhabditis elegans, and have provided an important model system for studying stem cells and their cell fate in vivo, in mammals. ...
A simple and rapid method for combining fluorescent in situ RNA hybridization (FISH) and immunofluorescence in the C. elegans germline
(2016-05-06)
Imaging of RNAs and proteins in specific tissues has opened ample avenues to understand gene expression during development. Recently, a fluorescent in situ RNA hybridization (FISH) method has been developed to analyze the ...
Blood‐based markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance)
(2016-09)
Circulating protein markers were assessed in patients with colorectal cancer (CRC) treated with cetuximab in CALGB 80203 to identify prognostic and predictive biomarkers. Patients with locally advanced or metastatic CRC ...
Acid ceramidase is upregulated in AML and represents a novel therapeutic target
(2016-12-13)
There is an urgent unmet need for new therapeutics in acute myeloid leukemia (AML) as standard therapy has not changed in the past three decades and outcome remains poor for most patients. Sphingolipid dysregulation through ...
Before-school running/walking club: Effects on student on-task behavior
(2016-02-01)
Before-school programs provide a good opportunity for children to engage in physical activity (PA) as well as im- prove their readiness to learn. The purpose of this study was to examine the effect of a before-school ...