Browsing Internal Medicine by Title

Now showing items 21-26 of 26

  • The role of PPARγ in carbon nanotube-elicited granulomatous lung inflammation 

    Huizar, Isham; Malur, Anagha; Patel, Janki; McPeek, Matthew; Dobbs, Larry; Wingard, Christopher J.; Barna, Barbara P.; Thomassen, Mary Jane (2013)
    BACKGROUND: Although granulomatous inflammation is a central feature of many disease processes, cellular mechanisms of granuloma formation and persistence are poorly understood. Carbon nanoparticles, which can be products ...

  • Sarcoidosis activates diverse transcriptional programs in bronchoalveolar lavage cells 

    Gharib, Sina A.; Malur, Anagha; Huizar, Isham; Barna, Barbara P.; Kavuru, Mani S.; Schnapp, Lynn M.; Thomassen, Mary J. (2016-07-26)
    Abstract Background Sarcoidosis is a multisystem immuno-inflammatory disorder of unknown etiology that most commonly involves the lungs. We hypothesized that an unbiased ...

  • Statins induce lethal effects in acute myeloblastic lymphoma cells within 72 hours 

    Burke, Lillian P.; Kukoly, Cynthia A. (East Carolina University, 2008-02)
    HMG-CoA Reductase inhibitors (statins) induce apoptosis in acute myeloid leukemia (AML) cells in vitro; however, the concentrations associated with cell death in AML cells are higher than those clinically tolerated during ...

  • Systematic review of diagnostic tests for vaginal trichomoniasis. 

    Patel, Sangnya R.; Wiese, Wilhelmine; Patel, Sanjay C.; Ohl, Christopher; Byrd, James C.; Estrada, Carlos A. (East Carolina University, 2000)
    Objective: To review critically and to summarize the evidence of diagnostic tests and culture media for the diagnosis of Trichomonas vaginitis. Methods: We performed a systematic review of literature indexed in MEDLINE of ...

  • The Tumor Suppressive Effects of T Cell Death-Associated Gene 8 in Blood Cancers 

    Justus, Calvin Richard (East Carolina University, 2017-03-16)
    In the early twentieth century Otto Warburg recognized a metabolic phenomenon that transpired in cancer cells, currently known as the Warburg Effect. Warburg discovered cancer cells favor glycolysis rather than oxidative ...

  • The transneuronal spread phenotype of herpes simplex virus type 1 infection of the mouse hind footpad. 

    Engel, Jeffrey P.; Madigan, Timothy C.; Peterson, Gary M. (East Carolina University, 1997-03)
    The mouse hind footpad inoculation model has served as a standard laboratory system for the study of the neuropathogenesis of herpes simplex virus type 1 (HSV-1) infection. The temporal and spatial distribution of viral ...