Browsing by Title
Now showing items 3206-3225 of 10629
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Emerging role of immune checkpoint blockade in pancreatic cancer
(2018-11-07)Immune checkpoint blockade (ICB) with programmed cell death protein-1(PD-1)/programmed death ligand -1(PD-L1) antibodies has revolutionized the management of several cancers, especially non-small cell lung cancer, melanoma, ... -
Emerging Role of Immune Checkpoint Blockade in Pancreatic Cancer
(2018-11-07)Immune checkpoint blockade (ICB) with programmed cell death protein-1(PD-1)/programmed death ligand -1(PD-L1) antibodies has revolutionized the management of several cancers, especially non-small cell lung cancer, melanoma, ... -
The Emerging Role of the Phosphatidylinositol 3-Kinase/ Akt/Mammalian Target of Rapamycin Signaling Network in Cancer Stem Cell Biology
(2010-08)The cancer stem cell theory entails the existence of a hierarchically organized, rare population of cells which are responsible for tumor initiation, self-renewal/maintenance, and mutation accumulation. The cancer stem ... -
Emerging roles for the pH-sensing G protein-coupled receptors in response to acidotic stress
(2015)Protons (hydrogen ions) are the simplest form of ions universally produced by cellular metabolism including aerobic respiration and glycolysis. Export of protons out of cells by a number of acid transporters is essential ... -
Emerging targeted therapies for melanoma treatment (Review)
(2014-08)Cutaneous melanoma is an aggressive cancer with a poor prognosis for patients with advanced disease. The identification of several key molecular pathways implicated in the pathogenesis of melanoma has led to the development ... -
Emerging Technology for Hazards Risk Reduction
(2009-09-18)The panelists include John Cole and Sarah Jamison, Brian Etherton, John Dorman, Ruth Little, and Noel Lee. Moderated by Tom Allen. Dr. Allen introduced the panel by posing a series of questions about how technology has ... -
Emotional Evidence of Change: Highlanders Experiences with Glacial Retreat in Peru
(East Carolina University, 2019-07-26)Global climate change is a phenomenon studied by some, but experienced by many. Communities in various places across the globe live with the physical and social effects of that phenomenon each day, with the most highly ... -
EMOTIONAL INTELLIGENCE COMPARISON OF HOSPITALITY AND COB UNDERGRADUATE STUDENTS
(East Carolina University, 2016-04-28)The purpose of this project is to better understand how College of Business undergraduate student academic performance is related to their level of emotional intelligence. It is also the goal of the study to examine the ... -
Emotions, Subjectivity, and the Environment: A Study of Environmental Involvement in a Campus Community
(East Carolina University, 2018-07-24)Awareness of environmental issues and the necessity for more sustainable solutions are common topics, particularly in the academia and on university campuses. Researchers and public figures have stressed multiple times the ... -
Emphasizing and Increasing Cardiac Rehabilitation Referrals in an Outpatient Cardiology Clinic
(2020-04-23)Heart disease is the second leading cause of death in NC. Cardiac rehabilitation (CR) is a class Ia recommendation for patients who have experienced a myocardial infarction (MI), percutaneous coronary intervention (PCI), ... -
EMPHASIZING PROFESSIONALISM TO ADDRESS TEACHER TURNOVER AT DILLARD MIDDLE SCHOOL
(East Carolina University, 2017-04-19)The dissertation examines the effects professional learning communities can have on improving teacher retention in a high needs school. The goal is to positively impact teacher retention by emphasizing and encouraging ... -
EMPLACEMENT AND GROWTH OF LARGE COMPLEX INTRUSIONS IN THE SHALLOW CRUST, HENRY MOUNTAINS, UTAH
(East Carolina University, 2011)Details of magma migration paths in the shallow crust are poorly understood, in part because there are few locations with well-preserved contacts of igneous intrusions and surrounding host rock. The exposures in the Henry ... -
Employee Assistance Program Utilization and User Satisfaction in an AbilityOne Program Compared to Non-AbilityOne Programs
(East Carolina University, 2011)The present study examines the effectiveness and utilization of an Employee Assistance Program (EAP) that was designed to serve 218 employees of an AbilityOne company whose mission it was "to improve the quality of life ... -
Employee Error: The Development, Validation, and Use of a Perceived Error Measure for Predicting Rumination, Burnout, and Counterproductive Work Behaviors
(East Carolina University, 2023-05-01)Errors are ubiquitous in organizations. Nonetheless, scholarly literature regarding workplace error has largely focused on low-rate catastrophic failures such as the Challenger, Columbia, and Chernobyl accidents. However, ... -
Employee Satisfaction in Sport: Development of a Multi-Dimensional Model in Coaching
(East Carolina University, 2010)Despite the overwhelming emphasis on job satisfaction in sport management research, scholars continue to advocate for the distinctiveness and importance of evaluating both job satisfaction and dissatisfaction. The purpose ... -
Employee Satisfaction with Onsite Clinic and Collaborative Care Pharmacy
(2019-10-15)Background: On-job-productivity loss (presenteeism), voluntary non-attendance at work (absenteeism), work-related injuries, and the wage replacement cost of disability are major factors promoting the need for employer-based ... -
Employment of GUPIXWIN Analysis System in Particle-Induced X-Ray (PIXE) Material Analysis
(East Carolina University, 2023-12-08)Particle-Induced X-Ray Emission (PIXE) is a multi-elemental material analysis method used for nondestructive analysis of samples. Improvements to the beam line and PIXE chamber in East Carolina University’s particle ... -
Enantiomeric Excess Determination of Primary Amines
(East Carolina University, 2016-04-28)Certain organic compounds can exist in two variations, known as enantiomers. Such compounds are characterized as being “chiral”. Enantiomers can exist in either R or S configurations, and the relative proportions of one ...