Browsing Dissertations and Theses by Title
Now showing items 2520-2539 of 2778
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The Transformation of the South as Presented in the Literature of Southern African American Women: Harriet Jacobs, Octavia Rogers, and Zora Neale Hurston
(East Carolina University, 2019-08-23)Incidents in the Life of a Slave Girl (1861) by Harriet Jacobs, The House of Bondage (1890) by Octavia Rogers Albert, and Their Eyes Were Watching God (1937) by Zora Neale Hurston provide accounts of historical time ... -
The Tree to Success: Using Decision Tree Analysis to Predict Employee Performance and Health
(East Carolina University, 2015-12-10)The purpose of the current study was to evaluate the relative advantages and disadvantages of a novel statistical technique within the context of personnel decision-making. Specifically, the use of decision tree analysis ... -
The Tumor Suppressive Effects of T Cell Death-Associated Gene 8 in Blood Cancers
(East Carolina University, 2017-03-16)In the early twentieth century Otto Warburg recognized a metabolic phenomenon that transpired in cancer cells, currently known as the Warburg Effect. Warburg discovered cancer cells favor glycolysis rather than oxidative ... -
The Union Soldier Monument Controversy at the Bentonville Battlefield State Historic Site
(East Carolina University, 2018-12-06)This thesis centers on a controversial monument initiative at the Bentonville Battlefield State Historic Site in Johnston County, North Carolina in 1994. The planned obelisk was to record the participation of the four Union ... -
The Value of Exposure: The Connection Between International Contact, Ethnocentrism, and Intercultural Sensitivity
(East Carolina University, 2019-08-13)As higher education continues on the path of globalization, a persistent focus is placed on creating internationally competent professionals. The most prominent method used to achieve this is through the internationalization ... -
THE VARIATION IN STRENGTH DECREMENT OF LOWER EXTREMITY MUSCLE GROUPS AND BIOMECHANICAL PLASTICITY IN OLDER ADULTS
(East Carolina University, 2019-08-13)Age-associated biomechanical plasticity (BP) has been established as the distal to proximal shift of joint mechanical output in old adults while walking. The cause of BP is still unknown, but changes in muscle strength of ... -
The Virginia Holocaust Museum: A Continuation of the Americanization of the Holocaust
(East Carolina University, 2017-12-13)This thesis examines the significance and effectiveness of Holocaust memory and remembrance in the United States with a closer look at the Virginia Holocaust Museum in Richmond, Virginia. It analyzes the role of the Holocaust ... -
THEOLOGICAL DISCUSSION AND INSTITUTIONAL CHANGE AT A CHURCH-RELATED INSTITUTION
(East Carolina University, 2012)This study explores the relationship between theological discussion and organizational change within a church-related institution. The qualitative case study examines the dialogue on a campus that received a Lilly Endowment ... -
Theoretical Probe to the Mechanism of Pt-catalyzed C-H Acylation Reaction: Possible Pathways for the Key Acylation Reaction of Platinacycles
(East Carolina University, 2019-08-23)Transition metal-catalyzed C-H bond functionalization offers a variety of desirable transformations of simple hydrocarbons to more complex compounds with applications being applied in pharmaceuticals to material sciences. ... -
THERAPEUTIC AND TOXICOLOGICAL EVALUATION OF BROAD-SPECTRUM ANTIMICROBIAL TRICLOSAN AS A CHEMOTHERAPEUTIC AGENT
(East Carolina University, 2019-05-07)Triclosan (TCS) is a phenolic antimicrobial incorporated in personal care products and medical devices. Interest in the antiproliferative properties of TCS has recently grown owing to its antilipogenic effects. Through the ... -
The therapeutic potential of Rho GTPase intervention
(East Carolina University, 2013)Small GTPases of the Rho family are well established regulators of critical cellular functions including cytoskeletal remodeling, motility, vesicle trafficking and cell cycle control. Additionally, aberrant signaling ... -
There Has Never Been Anything Truly Wrong with You
(East Carolina University, 2011)These stories are about obsessive, lonely people. The characters might seem insane but really, they are just lonely and maybe a bit neurotic. They are introspective characters who began life as sweet children, but grew ... -
"There Never Was a Good War or a Bad Peace" : Benjamin Franklin's diplomacy and the 1783 Treaty of Paris
(East Carolina University, 2014)This thesis is an analysis of Benjamin Franklin's actions and motivations as he negotiated the 1783 Treaty of Paris on behalf of the newly created United States. It examines three distinct phases beginning with Franklin's ... -
There’s No Place like Aztlán: The Quest for Queer Homeland through Re-visionism in Chicana Feminist Autohistorias
(East Carolina University, 2019-05-02)In this thesis, I explore how authors Gloria Anzaldúa, Cherríe Moraga, Helena María Viramontes, Ana Castillo, Alicia Gaspar de Alba, Sandra Cisneros, Lorna Dee Cervantes, Carla Trujillo and Felicia Luna Lemus represent ... -
THERE’S TWO SIDES TO EVERY STORY: EXPANDING THE NOMOLOGICAL NETWORK OF BURNOUT THROUGH THE PERSON-ENVIRONMENT INTERACTION
(East Carolina University, 8/5/2020)Burnout is a psychological syndrome consisting of emotional exhaustion, cynicism, and reduced personal accomplishment. It is associated with a depletion of intrinsic resources that results from prolonged exposure to ... -
Thermodynamic and Spectroscopic Investigations of Novel Antimicrobial Peptides containing Unnatural Amino Acids with Model Membrane Systems
(East Carolina University, 2011)With the over prescription and use of antibiotic drugs the evolution of drug resistant bacteria strains has become a world wide health crisis. In response to this crisis, the search for new drugs to kill bacteria via a ... -
Thermodynamic and spectroscopic studies of Cd²⁺ binding to the regulatory domain and full length human cardiac troponin C (HcTnC) : elucidating plausible Cd²⁺ binding sites
(East Carolina University, 2015)Toxic metals such as cadmium (Cd²⁺) have been shown to bind to and interfere with various calcium (Ca²⁺) binding proteins including the regulatory protein cardiac troponin C (cTnC). Recent structural data has shown that ... -
Thermodynamic and Structural Characterization of Cd(II) binding to human cardiac troponin C: Using Mutants and Truncated Constructs to Elucidate Cd(II) binding sites
(East Carolina University, 8/5/2020)Many biological processes rely on the presence of essential metals; therefore, maintaining the concentration of metals is paramount to homeostasis. Cadmium, Cd(II), is a toxic heavy metal that can disturb this delicate ... -
Thermodynamic Investigation into the Binding Properties of Cardiac Troponin (Human and Bovine)
(East Carolina University, 2010)Troponin is an integral protein in the mechanism of muscle contraction. In order to induce cardiac muscle contraction, Ca[superscript]2[superscript]+ must bind to the TnC subunit (calcium binding subunit) of troponin to ... -
Thermodynamic Investigation of Copper Binding to the Amyloid-Beta (A[beta]) Peptide
(East Carolina University, 2010)Alzheimer's disease is a fatal and neurodegenerative disease with as many as 5.3 million Americans living with the disease. One of the characteristic hallmarks of Alzheimer's is the amyloid plaques that build up around the ...