Browsing Dissertations by Title
Now showing items 217-236 of 1044
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Deciphering the impact of fructose metabolism on liver mitochondrial bioenergetics
(East Carolina University, 2021-12-07)Since its discovery in 1980, the interest in nonalcoholic fatty liver disease, the liver manifestation of metabolic syndrome, has expanded due to the growing impact on the world's health. Commonly characterized by ... -
Deciphering the Role of Long-chain Acyl-CoA Synthetase 6 in Brain Lipid Metabolism and Neuroprotection
(East Carolina University, 2021-04-27)The omega-3 fatty acid, docosahexaenoic acid (DHA), is highly enriched in the central nervous system (CNS) and thought to protect against neurological dysfunction. Due to its neuroprotective nature, DHA is widely considered ... -
Decisional Balance Among Potential ICD Recipients : Development Of The Implantable Cardioverter Defibrillator Decision Analysis Scale (ICD-DAS)
(East Carolina University, 2011)Sudden cardiac death is a well-documented public health problem resulting in 400,000 deaths in the U.S. annually. The Implantable Cardioverter Defibrillator (ICD) has demonstrated benefit in reducing mortality in at risk ... -
Decisions Under Duress: Influences on Official Decision Making During Superstorm Sandy
(East Carolina University, 2015-12-08)During impending storms, emergency managers and politicians are tasked with the difficult decision of whether or not to issue evacuation orders for their area. This study uses Superstorm Sandy as a case study and investigates ... -
The Declaration of Independence : A New Genre in Political Discourse or Mixed Genres in an Unlikely Medium?
(East Carolina University, 2011)The dissertation shows how mismatched content/medium relationships can supersede the responses of traditional pairings when the medium dominates the discursive power of the discourse. The dissertation, in part, looks at a ... -
Decolonizing Education : A Critical Discourse Analysis of Post-Secondary Humanities Textbooks
(East Carolina University, 2012)This dissertation examines nine post-secondary humanities textbooks published between 2001 and 2011 using an approach that includes both qualitative and quantitative methodology to analyze the written and visual content ... -
Delination of Coastal Shark Habitat within North Carolina Waters Using Acoustic Telemetry, Fisher-Independent Surveys, and Local Ecological Knowledge
(East Carolina University, 2016-07-20)Knowledge of shark habitat preferences and use patterns is important to effectively manage shark fisheries and account for interactions between sharks and species targeted by other fishery management or conservation efforts. ... -
DELINEATING THE MECHANISM OF AGGREGATE OR BIOFILM FORMATION IN THE LYME DISEASE SPIROCHETE BORRELIA BURGDORFERI
(East Carolina University, 2021-07-14)Borrelia burgdorferi, the spirochete causing Lyme disease, is transmitted to a vertebrate host by the bite of an infected Ixodes scapularis tick. The spirochete develops antibiotic resistance in humans likely due to the ... -
DELINEATING THE ROLE OF SOLUBLE CD25 AS AN IMMUNOREGULATORY MOLECULE THAT PROMOTES A LOW-ZONE IL-2 SIGNALING ENVIRONMENT FAVORABLE FOR THE SELECTION OF CD25HIGH FOXP3HIGH T CELLS
(East Carolina University, 2021-07-22)Autoimmune diseases develop due to the breakdown of tolerogenic mechanisms that normally maintain immune homeostasis. CD4+ CD25+ FOXP3+ regulatory T cells (Tregs) are critical in the maintenance of tolerance and the ... -
[Delta]-catenin: implications in prostate cancer progression
(East Carolina University, 2014)Prostate cancer (PCa) is the most commonly diagnosed cancer and the second most common cause of cancer death among men in the US. Due to the advances in research, the ability to detect and cure PCa has improved and led to ... -
Describing the Relationship Between Psychosocial Distress and Extent of Criminal Justice System Involvement for Men and Women in a Sober Living Environment
(East Carolina University, 2016-04-14)Symptoms of mental health and substance use disorders are prevalent for individuals involved in the criminal justice system and are associated with both costs to society and the individual. The purpose of this study was ... -
A descriptive exploratory study on how nurse educators use digital stories in the classroom
(East Carolina University, 2014)This study examines the experiences of 12 nurse educators using digital stories in undergraduate nursing courses. Two issues were explored: 1) How and for what purpose are nurse educators incorporating digital stories in ... -
DESIGN OF NOVICE PRINCIPAL INDUCTION FOR A CENTRAL NORTH CAROLINA SCHOOL DISTRICT
(East Carolina University, 2017-06-22)School districts across the nation are grappling with the issue of high principal turnover coupled with a decrease in number of experienced applicants to fill vacancies (Guterman, 2007; Hall, 2008; Johnson, 2005; United ... -
Detecting Cardiovascular Emotional Dampening: An Exploration of Emotional Dampening at Different Levels of Emotion Processing
(East Carolina University, 2017-07-05)Background: Cardiovascular emotional dampening is the phrase used to describe the inverse relationship between blood pressure and emotional responsivity. The emotional dampening literature is limited, but the phenomenon ... -
DETECTION AND DISTRIBUTION OF THE AMPHIBIAN FUNGAL DISEASE CHYTRIDIOMYCOSIS IN PERUVIAN AMPHIBIANS
(East Carolina University, 2012)Chytridiomycosis is an amphibian disease caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd;Longcore et al. 1999). This disease has been identified by the Amphibian Conservation Action Plan as one of the main ... -
Determining the role of the steroid hormone ecdysone in critical stages of Drosophila melanogaster early oogenesis
(East Carolina University, 2019-11-27)Reproductive function in many organisms, including Drosophila melanogaster, is controlled by steroid hormones. The main steroid hormone in Drosophila is ecdysone, which is structurally and functionally similar to estrogen. ... -
Developing a Behavioral Health Intervention Team for Moore County Schools
(East Carolina University, 2019-04-17)Student mental health has been a concern for school districts across the state of North Carolina as well as the nation. The purpose of this study was to improve the mental health, safety and welfare of students in Moore ... -
DEVELOPING A COMPREHENSIVE PROGRAM FOR ENGLISH LEARNER INSTRUCTION AT THE INDIVIDUAL SCHOOL LEVEL: A CHALLENGE IN SAMPSON COUNTY SCHOOLS
(East Carolina University, 2019-04-17)This study utilized Professional Learning Communities (PLC) of English Learner (EL) teachers in a collaborative process in the Union sub-district of Sampson County Schools to develop an EL Plan of Instruction. This group ... -
Developing a Latino-Adapted Parenting Program for Primary Care: A Delphi Study
(East Carolina University, 2018-07-19)Latino children suffer from many health disparities compared to their non-Latino peers. One way to minimize these health disparities is by empowering Latino parents through parenting support programs. Primary care agencies, ... -
DEVELOPING A PRINCIPAL INDUCTION PROGRAM FOR CRAVEN COUNTY SCHOOLS
(East Carolina University, 2015-04-28)The demands of principals have increased drastically over the years and principals are overwhelmed as they accept the responsibility for an entire school. With an emphasis on performance and accountability and realizing ...