Browsing Kinesiology by Title
Now showing items 60-79 of 89
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NEURAL MECHANISMS CONTRIBUTE TO THE AGE RELATED INCREASE IN METABOLIC COST OF GAIT
(East Carolina University, 2010)Aging is associated with biomechanical and physiological changes in several organ systems, including neural changes of voluntary movement. One manifestation of age-related changes in neural control of gait is the increased ... -
No difference in the skeletal muscle angiogenic response
(East Carolina University, 2007-11)Ischaemia-induced skeletalmuscle angiogenesis is impaired in aged compared with young mice. In humans, vascular endothelial growth factor (VEGF) mRNA and protein following an acute exercise bout are lower in aged compared ... -
Obese Children Have a Lower Lipolytic Response to an Acute Bout of Exercise When Compared to Lean
(East Carolina University, 2010)Over 17% of American children are obese. These are epidemic proportions considering the associated risk of heart disease and Type 2 diabetes. Excess fat is caused from an imbalance in energy stored versus energy expended. ... -
Paired Effects of Dietary Leucine Supplementation and Overload on Protein Translational Signaling and Hypertrophy in Aged Rat Skeletal Muscle
(East Carolina University, 2012)Sarcopenia is an age-associated disorder that causes loss of skeletal muscle mass, particularly in type II (fast-twitch) muscle fibers. This loss in muscle mass can cause disability, reductions in the quality of life, and ... -
Physical activity across the curriculum: year one process evaluation results
(East Carolina University, 2008-07-07)Background: Physical Activity Across the Curriculum (PAAC) is a 3-year elementary school-based intervention to determine if increased amounts of moderate intensity physical activity performed in the classroom will diminish ... -
Physical Activity, Academic Performance, and Physical Self-Description in Adolescent Females
(East Carolina University, 2009)Despite the many health benefits of being physically active, nearly a quarter of U.S. adults and adolescents report no participation in leisure-time physical activity. It is recommended that children and adolescents ... -
The Physiological and Pathological Role of Mitochondrial Calcium in the Diabetic Heart
(East Carolina University, 2011)Diabetic patients are more susceptible to ischemia/reperfusion injury and cardiac dysfunction likely due alterations in mitochondrial calcium handling. The purpose of this work was to determine if redox-dependent changes ... -
POSITIVE VS. NEGATIVE MUSCLE WORK OF NON-LEVEL WALKING IN LEAN AND OBESE ADULTS.
(East Carolina University, 2010)When walking on non-level surfaces at a constant speed, an individual's total mechanical energy will increase when walking up an incline, and will decrease an equal amount going down a decline. Total muscle work performed ... -
Proximal vs. Distal Fascicle Behavior within the Biceps Femoris Long Head at Different Muscle Activation Levels
(East Carolina University, 2013)Hamstring strains have been shown to occur more often in the long head of the biceps femoris (BFLH) than the semitendinosus and semimembranosus, with most injuries occurring in the proximal half of the BFLH. Muscle modeling ... -
The Region Specific Influence of Estradiol on In-Vivo Lipolysis in Subcutaneous Adipose Tissue in Overweight-to-Moderately-Obese Premenopausal Women
(East Carolina University, 2012)Premenopausal women demonstrate preferential accumulation of adiposity in the gynoid region, a distribution which shifts towards the abdominal region after the menopausal transition. Although estrogen is implicated as a ... -
Regulation of GLUT4 expression in denervated skeletal muscle
(East Carolina University, 2009-03)Denervation by sciatic nerve resection causes decreased muscle glucose transporter 4 (GLUT4) expression, but little is known about the signaling events that cause this decrease. Experiments were designed to test the ... -
REGULATION OF LIPOLYSIS BY [BETA]-ADRENERGIC ACTIVATION AND EXERCISE IN OBESE AFRICAN-AMERICAN AND CAUCASIAN WOMEN
(East Carolina University, 2012)African-American women (AAW) are twice as likely to be obese as Caucasian women (CW); however, previous in-vitro studies have shown that AAW have higher densities of beta-adrenergic receptors (B-AR) in the subcutaneous ... -
Regulation of Lipolysis By Perilipin : influence of Obesity and Exercise Training
(East Carolina University, 2010)Obesity is the result of excess energy storage due to an imbalance between energy storage and energy utilization. Excess energy is stored as triacylglycerol (TAG) in adipose tissue in various regions throughout the body. ... -
The relationship between visual steadiness and force steadiness in young and old adults
(East Carolina University, 2013)Old adults exhibit a decrease in muscle force steadiness and visual capability compared to young adults. Many studies investigating force steadiness have used a visual target as the stimulus for modulating muscle force. ... -
Relationships between Adipose Tissue and Cytokine Responses to a Randomized Controlled Exercise Training Intervention
(East Carolina University, 2008-04)Adipose-derived cytokines play a prominent role in mediating the metabolic consequences of obesity and excess body fat. Given this, we hypothesized that alterations in adipose tissue stores incurred with exercise training ... -
Relative fat oxidation is higher in children than adults
(East Carolina University, 2007-08-16)Background: Prepubescent children may oxidize fatty acids more readily than adults. Therefore, dietary fat needs would be higher for children compared with adults. The dietary fat recommendations are higher for children 4 ... -
Review of microdialysis in brain tumors, from concept to application: First Annual Carolyn Frye-Halloran Symposium
(East Carolina University, 2004-01)In individuals with brain tumors, pharmacodynamic and pharmacokinetic studies of therapeutic agents have historically used analyses of drug concentrations in serum or cerebrospinal fluid, which unfortunately do not necessarily ... -
THE ROLE OF LONG-CHAIN ACYL-COENZYME A SYNTHETASE 1 (ACSL-1) IN LIPID METABOLISM IN HUMAN SKELETAL MUSCLE PRIMARY MYOTUBES.
(East Carolina University, 2011)Obesity is considered a major health threat to the U.S. due to being a strong risk factor for developing type 2 diabetes and other metabolic diseases. The prevalence and severity of obesity is even greater among some ... -
A sex-specific relationship between capillary density and anaerobic threshold
(East Carolina University, 2009-04)Although both capillary density and peak oxygen consumption (VO2) improve with exercise training, it is difficult to find a relationship between these two measures. It has been suggested that peak VO2 may be more related ... -
A single dose of metformin improves whole body insulin sensitivity and alters cellular redox state in skeletal muscle of Zucker fa/fa rats
(East Carolina University, 2010)Energy balance is considered a fundamental requirement of life forms from single cell organisms to higher mammals such as humans. Unfortunately, our species has also discovered the detrimental metabolic responses to excess ...