Now showing items 182-201 of 358

  • Genetic Architecture of Conspicuous Red Ornaments in Female Threespine Stickleback 

    Yong, Lengxob; Peichel, Catherine L.; McKinnon, Jeffrey S. (2015-12)
    Explaining the presence of conspicuous female ornaments that take the form of male-typical traits has been a longstanding challenge in evolutionary biology. Such female ornaments have been proposed to evolve via both ...
  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function 

    Pattaro, Cristian; Teumer, Alexander; Gorski, Mathias; Chu, Audrey Y.; Li, Man; Mijatovic, Vladan; Garnaas, Maija; Tin, Adrienne; Sorice, Rossella; Li, Yong; Taliun, Daniel; Olden, Matthias; Foster, Meredith; Yang, Qiong; Chen, Ming-Huei; Pers, Tune H.; Johnson, Andrew D.; Ko, Yi-An; Fuchsberger, Christian; Tayo, Bamidele; Nalls, Michael A.; Feitosa, Mary F.; Isaacs, Aaron; Dehghan, Abbas; d'Adamo, Pio; Adeyemo, Adebowale; Dieffenbach, Aida Karina; Zonderman, Alan B.; Nolte, Ilja M.; van der Most, Peter J.; Wright, Alan F.; Shuldiner, Alan R.; Morrison, Alanna C.; Hofman, Albert; Smith, Albert V.; Dreisbach, Albert W.; Franke, Andre; Uitterlinden, Andre G.; Metspalu, Andres; Tonjes, Anke; Lupo, Antonio; Robino, Antonietta; Johansson, Åsa; Demirkan, Ayse; Kollerits, Barbara; Freedman, Barry I.; Ponte, Belen; Oostra, Ben A.; Paulweber, Bernhard; Krämer, Bernhard K.; Mitchell, Braxton D.; Buckley, Brendan M.; Peralta, Carmen A.; Hayward, Caroline; Helmer, Catherine; Rotimi, Charles N.; Shaffer, Christian M.; Müller, Christian; Sala, Cinzia; van Duijn, Cornelia M.; Saint-Pierre, Aude; Ackermann, Daniel; Shriner, Daniel; Ruggiero, Daniela; Toniolo, Daniela; Lu, Yingchang; Cusi, Daniele; Czamara, Darina; Ellinghaus, David; Siscovick, David S.; Ruderfer, Douglas; Gieger, Christian; Grallert, Harald; Rochtchina, Elena; Atkinson, Elizabeth J.; Holliday, Elizabeth G.; Boerwinkle, Eric; Salvi, Erika; Bottinger, Erwin P.; Murgia, Federico; Rivadeneira, Fernando; Ernst, Florian; Kronenberg, Florian; Hu, Frank B.; Navis, Gerjan J.; Curhan, Gary C.; Ehret, George B.; Homuth, Georg; Coassin, Stefan; Thun, Gian-Andri; Pistis, Giorgio; Gambaro, Giovanni; Malerba, Giovanni; Montgomery, Grant W.; Eiriksdottir, Gudny; Jacobs, Gunnar; Li, Guo; Wichmann, H-Erich; Campbell, Harry; Schmidt, Helena; Wallaschofski, Henri; Völzke, Henry; Brenner, Hermann; Kroemer, Heyo K.; Kramer, Holly; Lin, Honghuang; Leach, I. Mateo; Ford, Ian; Guessous, Idris; Rudan, Igor; Prokopenko, Inga; Borecki, Ingrid B.; Heid, Iris M.; Kolcic, Ivana; Persico, Ivana; Jukema, J. Wouter; Wilson, James F.; Felix, Janine F.; Divers, Jasmin; Lambert, Jean-Charles; Stafford, Jeanette M.; Gaspoz, Jean-Michel; Smith, Jennifer A.; Faul, Jessica D.; Wang, Jie Jin; Ding, Jingzhong; Hirschhorn, Joel N.; Attia, John; Whitfield, John B.; Chalmers, John; Viikari, Jorma; Coresh, Josef; Denny, Joshua C.; Karjalainen, Juha; Fernandes, Jyotika K.; Endlich, Karlhans; Butterbach, Katja; Keene, Keith L.; Lohman, Kurt; Portas, Laura; Launer, Lenore J.; Lyytikäinen, Leo-Pekka; Yengo, Loic; Franke, Lude; Ferrucci, Luigi; Rose, Lynda M.; Kedenko, Lyudmyla; Rao, Madhumathi; Struchalin, Maksim; Kleber, Marcus E.; Cavalieri, Margherita; Haun, Margot; Cornelis, Marilyn C.; Ciullo, Marina; Pirastu, Mario; de Andrade, Mariza; McEvoy, Mark A.; Woodward, Mark; Adam, Martin; Cocca, Massimiliano; Nauck, Matthias; Imboden, Medea; Waldenberger, Melanie; Pruijm, Menno; Metzger, Marie; Stumvoll, Michael; Evans, Michele K.; Sale, Michele M.; Kähönen, Mika; Boban, Mladen; Bochud, Murielle; Rheinberger, Myriam; Verweij, Niek; Bouatia-Naji, Nabila; Martin, Nicholas G.; Hastie, Nick; Probst-Hensch, Nicole; Soranzo, Nicole; Devuyst, Olivier; Raitakari, Olli; Gottesman, Omri; Franco, Oscar H.; Polasek, Ozren; Gasparini, Paolo; Munroe, Patricia B.; Ridker, Paul M.; Mitchell, Paul; Muntner, Paul; Meisinger, Christa; Smit, Johannes H.; Kovacs, Peter; Wild, Philipp S.; Froguel, Philippe; Rettig, Rainer; Mägi, Reedik; Biffar, Reiner; Schmidt, Reinhold; Middelberg, Rita P. S.; Carroll, Robert J.; Penninx, Brenda W.; Scott, Rodney J.; Katz, Ronit; Sedaghat, Sanaz; Wild, Sarah H.; Kardia, Sharon L. R.; Ulivi, Sheila; Hwang, Shih-Jen; Enroth, Stefan; Kloiber, Stefan; Trompet, Stella; Stengel, Benedicte; Hancock, Stephen J.; Turner, Stephen T.; Rosas, Sylvia E.; Stracke, Sylvia; Harris, Tamara B.; Zeller, Tanja; Zemunik, Tatijana; Lehtimäki, Terho; Illig, Thomas; Aspelund, Thor; Nikopensius, Tiit; Esko, Tonu; Tanaka, Toshiko; Gyllensten, Ulf; Völker, Uwe; Emilsson, Valur; Vitart, Veronique; Aalto, Ville; Gudnason, Vilmundur; Chouraki, Vincent; Chen, Wei-Min; Igl, Wilmar; März, Winfried; Koenig, Wolfgang; Lieb, Wolfgang; Loos, Ruth J. F.; Liu, Yongmei; Snieder, Harold; Pramstaller, Peter P.; Parsa, Afshin; O'Connell, Jeffrey R.; Susztak, Katalin; Hamet, Pavel; Tremblay, Johanne; de Boer, Ian H.; Böger, Carsten A.; Goessling, Wolfram; Chasman, Daniel I.; Köttgen, Anna; Kao, W. H. Linda; Fox, Caroline S. (2016-01)
    Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular ...
  • Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial 

    Keene, Keith L.; Chen, Wei-Min; Chen, Fang; Williams, Stephen R.; Elkhatib, Stacey D.; Hsu, Fang-Chi; Mychaleckyj, Josyf C.; Doheny, Kimberly F.; Pugh, Elizabeth W.; Ling, Hua; Laurie, Cathy C.; Gogarten, Stephanie M.; Madden, Ebony B.; Worrall, Bradford B.; Sale, Michele M. (2014-08)
    Background: B vitamins play an important role in homocysteine metabolism, with vitamin deficiencies resulting in increased levels of homocysteine and increased risk for stroke. We performed a genome-wide association study ...
  • The Genetic Basis of Pigmentation Variation in Domesticated Zebra Finches 

    Pathak,Shaivya (2014)
    The zebra finch is the most common estrildid finch native to Australia and Southeast Asia. The zebra finch has also been domesticated and is now a common pet and experimental model system for research. As part of the ...
  • Genetic mapping of the female mimic morph locus in the ruff 

    Farrell, Lindsay L.; Burke, Terry; Slate, Jon; McRae, Susan B.; Lank, David B. (2013)
    Background Ruffs (Aves: Philomachus pugnax) possess a genetic polymorphism for male mating behaviour resulting in three permanent alternative male reproductive morphs: (i) territorial ‘Independents’, (ii) non-territorial ...
  • A Genetic Mosaic Screen Reveals Ecdysone-Responsive Genes Regulating Drosophila Oogenesis 

    Ables, Elizabeth Tweedie; Hwang, Grace H.; Finger, Danielle S.; Hinnant, Taylor D.; Drummond-Barbosa, Daniela (2016-08)
    Multiple aspects of Drosophila oogenesis, including germline stem cell activity, germ cell differentiation, and follicle survival, are regulated by the steroid hormone ecdysone. While the transcriptional targets of ecdysone ...
  • A Genetic Screen for Mcm10: Interactions Between Mcm10 and Deficiency Regions on the Third Chromosome of Drosophila Melanogaster 

    Anstead, Bryan (2015)
    Mis-regulation of the Mcm10 gene has been linked with multiple forms of cancer, including many forms of breast cancer (Thu, Y. 2014). Despite this, the role of Mcm10 in cancer is not yet fully known. One way to study a ...
  • Genetic variation corroborates subspecific delimitation in the Namib fog-basking beetle, (Haag) (Tenebrionidae, Coleoptera) 

    Lamb, Trip; Pollard, Rachel; Bond, Jason E. (2013)
    The fog-basking beetle, Onymacris unguicularis (Haag, 1875), is currently listed as a polytypic form comprising two subspecies. A flightless substrate specialist, the beetleis endemic to vegetationless dunes in the Namib, ...
  • Genome Analysis of Planctomycetes Inhabiting Blades of the Red Alga 

    Kim, Jay W.; Brawley, Susan H.; Prochnik, Simon; Chovatia, Mansi; Grimwood, Jane; Jenkins, Jerry W.; LaButti, Kurt; Mavromatis, Konstantinos; Nolan, Matt; Zane, Matthew; Schmutz, Jeremy; Stiller, John W.; Grossman, Arthur R. (2016-03)
    Porphyra is a macrophytic red alga of the Bangiales that is important ecologically and economically. We describe the genomes of three bacteria in the phylum Planctomycetes (designated P1, P2 and P3) that were isolated from ...
  • Genome sequencing and analysis of the paclitaxel-producing endophytic fungus NRRL 62431 

    Yang, Yanfang; Zhao, Hainan; Barrero, Roberto A; Zhang, Baohong; Sun, Guiling; Wilson, Iain W.; Xie, Fuliang; Walker, Kevin D; Parks, Joshua W; Bruce, Robert; Guo, Guangwu; Chen, Li; Zhang, Yong; Huang, Xin; Tang, Qi; Liu, Hongwei; Bellgard, Matthew I; Qiu, Deyou; Lai, Jinsheng; Hoffman, Angela (2014)
    Background Paclitaxel (Taxol™) is an important anticancer drug with a unique mode of action. The biosynthesis of paclitaxel had been considered restricted to the Taxus species until it was discovered in Taxomyces andreanae, ...
  • Genome-wide and molecular evolution analysis of the subtilase gene family in 

    Cao, Jun; Han, Xi; Zhang, Ticao; Yang, Yongping; Huang, Jinling; Hu, Xiangyang (2014-12)
    Background Vitis vinifera (grape) is one of the most economically significant fruit crops in the world. The availability of the recently released grape genome sequence offers an opportunity to identify and analyze some ...
  • Genome-Wide Functional Analysis of the Cotton Transcriptome by Creating an Integrated EST Database 

    Xie, Fuliang; Sun, Guiling; Stiller, John W.; Zhang, Baohong (2011)
    A total of 28,432 unique contigs (25,371 in consensus contigs and 3,061 as singletons) were assembled from all 268,786 cotton ESTs currently available. Several in silico approaches [comparative genomics, Blast, Gene Ontology ...
  • Genome-Wide Identification And Expression Analysis Of TCP Transcription Factors In Cotton 

    Ma, Jun (East Carolina University, 2015)
    TCP proteins are plant-specific transcription factors known to perform a variety of physiological functions during plant growth and development. In the current study, we performed for the first time the comprehensive ...
  • Genome-Wide Identification of R2R3-MYB Genes and Expression Analyses During Abiotic Stress in 

    He, Qiuling; Jones, Don C.; Li, Wei; Xie, Fuliang; Ma, Jun; Sun, Runrun; Wang, Qinglian; Zhu, Shuijin; Zhang, Baohong (2016-03)
    The R2R3-MYB is one of the largest families of transcription factors, which have been implicated in multiple biological processes. There is great diversity in the number of R2R3-MYB genes in different plants. However, there ...
  • Genome-Wide Meta-Analysis of Homocysteine and Methionine Metabolism Identifies Five One Carbon Metabolism Loci and a Novel Association of with Ischemic Stroke 

    Williams, Stephen R.; Yang, Qiong; Chen, Fang; Liu, Xuan; Keene, Keith L.; Jacques, Paul; Chen, Wei-Min; Weinstein, Galit; Hsu, Fang-Chi; Beiser, Alexa; Wang, Liewei; Bookman, Ebony; Doheny, Kimberly F.; Wolf, Philip A.; Zilka, Michelle; Selhub, Jacob; Nelson, Sarah; Gogarten, Stephanie M.; Worrall, Bradford B.; Seshadri, Sudha; Sale, Michèle M. (2014-03)
    Circulating homocysteine levels (tHcy), a product of the folate one carbon metabolism pathway (FOCM) through the demethylation of methionine, are heritable and are associated with an increased risk of common diseases such ...
  • The genomes of two key bumblebee species with primitive eusocial organization 

    Sadd, Ben M.; Barribeau, Seth M.; Bloch, Guy; de Graaf, Dirk C.; Dearden, Peter; Elsik, Christine G.; Gadau, Jürgen; Grimmelikhuijzen, Cornelis J.; Hasselmann, Martin; Lozier, Jeffrey D.; Robertson, Hugh M.; Smagghe, Guy; Stolle, Eckart; Van Vaerenbergh, Matthias; Waterhouse, Robert M.; Bornberg-Bauer, Erich; Klasberg, Steffen; Bennett, Anna K.; Câmara, Francisco; Guigó, Roderic; Hoff, Katharina; Mariotti, Marco; Munoz-Torres, Monica; Murphy, Terence; Santesmasses, Didac; Amdam, Gro V.; Beckers, Matthew; Beye, Martin; Biewer, Matthias; Bitondi, Márcia M.; Blaxter, Mark L.; Bourke, Andrew F.; Brown, Mark J. F.; Buechel, Severine D.; Cameron, Rossanah; Cappelle, Kaat; Carolan, James C.; Christiaens, Olivier; Ciborowski, Kate L.; Clarke, David F.; Colgan, Thomas J.; Collins, David H.; Cridge, Andrew G.; Dalmay, Tamas; Dreier, Stephanie; du Plessis, Louis; Duncan, Elizabeth; Erler, Silvio; Evans, Jay D.; Falcon, Tiago; Flores, Kevin; Freitas, Flávia C.; Fuchikawa, Taro; Gempe, Tanja; Hartfelder, Klaus; Hauser, Frank; Helbing, Sophie; Humann, Fernanda C.; Irvine, Frano; Jermiin, Lars S.; Johnson, Claire E.; Johnson, Reed M.; Jones, Andrew K; Kadowaki, Tatsuhiko; Kidner, Jonathan H.; Koch, Vasco; Köhler, Arian; Kraus, F. B.; Lattorff, H. M. G.; Leask, Megan; Lockett, Gabrielle A.; Mallon, Eamonn B.; Antonio, David S. Marco; Marxer, Monika; Meeus, Ivan; Moritz, Robin F.; Nair, Ajay; Näpflin, Kathrin; Nissen, Inga; Niu, Jinzhi; Nunes, Francis M.; Oakeshott, John G.; Osborne, Amy; Otte, Marianne; Pinheiro, Daniel G.; Rossié, Nina; Rueppell, Olav; Santos, Carolina G.; Schmid-Hempel, Regula; Schmitt, Björn D.; Schulte, Christina; Simões, Zilá L.; Soares, Michelle P.; Swevers, Luc; Winnebeck, Eva C.; Wolschin, Florian; Yu, Na; Zdobnov, Evgeny M.; Aqrawi, Peshtewani K.; Blankenburg, Kerstin P.; Coyle, Marcus; Francisco, Liezl; Hernandez, Alvaro G.; Holder, Michael; Hudson, Matthew E.; Jackson, LaRonda; Jayaseelan, Joy; Joshi, Vandita; Kovar, Christie; Lee, Sandra L.; Mata, Robert; Mathew, Tittu; Newsham, Irene F.; Ngo, Robin; Okwuonu, Geoffrey; Pham, Christopher; Pu, Ling-Ling; Saada, Nehad; Santibanez, Jireh; Simmons, DeNard; Thornton, Rebecca; Venkat, Aarti; Walden, Kimberly K.; Wu, Yuan-Qing; Debyser, Griet; Devreese, Bart; Asher, Claire; Blommaert, Julie; Chipman, Ariel D.; Chittka, Lars; Fouks, Bertrand; Liu, Jisheng; O’Neill, Meaghan P.; Sumner, Seirian; Puiu, Daniela; Qu, Jiaxin; Salzberg, Steven L.; Scherer, Steven E.; Muzny, Donna M.; Richards, Stephen; Robinson, Gene E.; Gibbs, Richard A.; Schmid-Hempel, Paul; Worley, Kim C. (2015-04-24)
    Background The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies. ...
  • GILLNET CALIBRATION FOR SPINY DOGFISH ABUNDANCE ASSESSMENT 

    Wright, Garry Lyn, Jr. (East Carolina University, 2013)
    Spiny dogfish (Squalus acanthias) is one of the most abundant species in the Northwest Atlantic however; the stocks collapsed in the late 1990s and were declared overfished April 3, 1998 by the Atlantic States Marine ...
  • Government and Medicine: the evolution of the Chinese health care system 

    Carr, Brittany L. (2011-04-29)
    China’s diverse political history offers the unique opportunity to explore how a nation’s government impacts its approach to medicine and public health. The author found a correlation between Chinese government and health. ...
  • Growth and Survival of Leiostomus Xanthurus (Spot) in Man-Made and Natural Wetlands 

    West, Terry (East Carolina University, 1990-04)
    Growth and survival of the benthic feeding fish Leiosrotnus xanrhurus (‘spot”) was compared in man-made (Project Area 2) and natural oligohaline subtributaries of the Pamlico River Estuary. Experiments during 1984 defined ...
  • Habitat and Scale Shape the Demographic Fate of the Keystone Sea Urchin in Mediterranean Macrophyte Communities 

    Prado, Patricia; Tomas, Fiona; Pinna, Stefania; Farina, Simone; Roca, Guillem; Ceccherelli, Giulia; Romero, Javier; Alcoverro, Teresa (2012)
    Demographic processes exert different degrees of control as individuals grow, and in species that span several habitats and spatial scales, this can influence our ability to predict their population at a particular ...