Browsing Other Campus Research by Title
Now showing items 676-695 of 1103
-
N6-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression
(2018-07-27)The mRNA modification N6-methyladenosine (m6A) is involved in many post-transcriptional regulatory processes including mRNA stability and translational efficiency. However, it is also imperative to correlate these processes ... -
N6-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression
(2018-07-27)The mRNA modification N6-methyladenosine (m6A) is involved in many post- transcriptional regulatory processes including mRNA stability and translational efficiency. However, it is also imperative to correlate these processes ... -
N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs
(2017-09)Post-transcriptional regulation of mRNA during oxygen deprivation, or hypoxia, can affect the survivability of cells. Hypoxia has been shown to increase stability of a subset of ischemia-related mRNAs, including VEGF. RNA ... -
The National Clinical Assessment Tool for Medical Students in the Emergency Department (NCAT-EM)
(2018-01)Introduction: Clinical assessment of medical students in emergency medicine (EM) clerkships is a highly variable process that presents unique challenges and opportunities. Currently, clerkship directors use institution-specific ... -
A National Study of Social Media, Television, Radio, and Internet Usage of Adults by Sexual Orientation and Smoking Status: Implications for Campaign Design
(2017-04-21)Background: Smoking rates among lesbian, gay, and bisexual (LGB) people significantly exceed that of heterosexuals. Media interventions are an important part of tobacco control efforts, but limited information is available ... -
National Trends in Cessation Counseling, Prescription Medication Use, and Associated Costs Among US Adult Cigarette Smokers
(2019-05-24)Importance: Cigarette smoking is the leading cause of preventable disease and death in the United States. When used separately or in combination, smoking cessation counseling and cessation medications have been associated ... -
ncreased glycemic variability is independently associated with length of stay and mortality in noncritically ill hospitalized patients
(2013-10-29)OBJECTIVE: To investigate the association between glycemic variability (GV) and both length of stay (LOS) and 90-day mortality in noncritically ill hospitalized patients. RESEARCH DESIGN AND METHODS: This study ... -
Near-infrared spectroscopy detects age-related differences in skeletal muscle oxidative function: promising implications for geroscience
(2018-02)Age is the greatest risk factor for chronic disease and is associated with a marked decline in functional capacity and quality of life. A key factor contributing to loss of function in older adults is the decline in skeletal ... -
Nearshore mixing and nutrient delivery along the western Antarctic Peninsula
(2017-10)The surface waters of the Southern Ocean play a key role in the global climate and carbon cycles by promoting growth of some of the world’s largest phytoplankton blooms. Several studies have emphasized the importance of ... -
Nearshore mixing and nutrient delivery along the western Antarctic Peninsula
(2017)The surface waters of the Southern Ocean play a key role in the global climate and carbon cycles by promoting growth of some of the world’s largest phytoplankton blooms. Several studies have emphasized the importance of ... -
Necrotizing enterocolitis leads to disruption of tight junctions and increase in gut permeability in a mouse model
(2018-11-27)Background: Necrotizing enterocolitis (NEC) is a leading cause of death in preterm infants. Neonates weighing <1500 grams are at the highest risk for acquiring NEC, with a prevalence of nearly 7-10%, mortality up to 30%, ... -
Nectin like -5 overexpression correlates with the malignant phenotype in cutaneous melanoma
(2012-08-26)NECL-5 is involved in regulating cell–cell junctions, in cooperation with cadherins, integrins and platelet-derived growth factor receptor, that are essential for intercellular communication. Its role in malignant ... -
Nestin in immature embryonic neurons affects axon growth cone morphology and Semaphorin3a sensitivity
(2019-05-01)Correct wiring in the neocortex requires that responses to an individual guidance cue vary among neurons in the same location, and within the same neuron over time. Nestin is an atypical intermediate filament expressed ... -
The net effects of medical malpractice tort reform on health insurance losses: the Texas experience
(2017-11-24)In this paper, we examine the influence of medical malpractice tort reform on the level of private health insurance company losses incurred. We employ a natural experiment framework centered on a series of tort reform ... -
Neuroantigen-specific, tolerogenic vaccines: GM-CSF is a fusion partner that facilitates tolerance rather than immunity to dominant self-epitopes of myelin in murine models of experimental autoimmune encephalomyelitis (EAE)
(2011-12-30)BACKGROUND: Vaccination strategies that elicit antigen-specific tolerance are needed as therapies for autoimmune disease. This study focused on whether cytokine-neuroantigen (NAg) fusion proteins could inhibit disease in ... -
Neuroleptanalgesia for acute abdominal pain: a systematic review
(2019-02-26)Background: Acute abdominal pain (AAP) comprises up to 10% of all emergency department (ED) visits. Current pain management practice is moving toward multi-modal analgesia regimens that decrease opioid use. Objective: ... -
Neuron-derived transthyretin modulates astrocytic glycolysis in hormone-independent manner
(2017-11-20)It has been shown that neurons alter the expression of astrocytic metabolic enzymes by secretion of until now unknown molecule(s) into extracellular fluid. Here, we present evidence that neuron-derived transthyretin (TTR) ...