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Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia
(2016-02-08)
Craniofacial microsomia (CFM) is a rare congenital anomaly that involves immature derivatives from the first and second pharyngeal arches. The genetic pathogenesis of CFM is still unclear. Here we interrogate 0.9 million ...
Genetic Architecture of Conspicuous Red Ornaments in Female Threespine Stickleback
(2016-03)
Explaining the presence of conspicuous female ornaments that take the form of male-typical traits has been a longstanding challenge in evolutionary biology. Such female ornaments have been proposed to evolve via both ...
Gene Regulatory Evolution During Speciation in a Songbird
(2016-03-10)
Over the last decade, tremendous progress has been made toward a comparative un- derstanding of gene regulatory evolution. However, we know little about how gene regulation evolves in birds, and how divergent genomes ...
Akhenaten’s Amarna in New Kingdom Egypt: Relations of Landscape and Ideology
(2016-08)
a few years after Pharaoh amenophis iV (ruled ca.1353– 1337 in the Eighteenth dynasty during new Kingdom Egypt) had assumed the highest office in Thebes, he decided to radically reorganize and redirect the Egyptian political ...
An Emerging Natural History in the Development, Mechanisms and Worldwide Prevalence of Major Mental Disorders
(2016-12-30)
Conciliating recent findings from molecular genetics, evolutionary biology, and clinical observations together point to new understandings regarding the mechanism, development and the persistent worldwide prevalence of ...
Airway observations during upper endoscopy predicting obstructive sleep apnea
(2016-06-10)
Background This pilot study examined airway characteristics during upper endoscopy to determine who is at high risk for obstructive sleep apnea.
Methods Patients undergoing routine upper endoscopy were divided into 2 ...
"May I Buy a Pack of Marlboros, Please?" A Systematic Review of Evidence to Improve the Validity and Impact of Youth Undercover Buy Inspections
(2016-04-06)
Most smokers become addicted to tobacco products before they are legally able to pur- chase these products. We systematically reviewed the literature on protocols to assess underage purchase and their ecological validity. ...
“Moving Toward Healthy”: Insights Into Food Choices of Mothers in Residential Recovery
(2016-11)
This study utilized participatory and potentially empowering qualitative research methods of photo-elicitation and face- to-face interviews to investigate food choices of mothers living with their children in a residential ...
EPG5-related Vici syndrome: a paradigm of neurodevelopmental disorders with defective autophagy
(2016)
Vici syndrome is a progressive neurodevelopmental multisystem disorder due to recessive mutations in the key autophagy gene EPG5. We report genetic, clinical, neuroradiological, and neuropathological features of 50 children ...
Diffusion and perfusion weighted magnetic resonance imaging for tumor volume definition in radiotherapy of brain tumors
(2016-09-21)
Accurate target volume delineation is crucial for the radiotherapy of tumors. Diffusion and perfusion magnetic resonance imaging (MRI) can provide functional information about brain tumors, and they are able to detect tumor ...