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Lexical diversity in Parkinson’s disease
(2015-03-02)
Background: Parkinson’s disease (PD) is a neurodegenerative syndrome of the basal ganglia (BG) believed to disrupt cortical-subcortical pathways critical to motor, cognitive and expressive language function. Recent studies ...
Biophysical Mechanisms Mediating Fibrin Fiber Lysis
(2017-05-28)
The formation and dissolution of blood clots is both a biochemical and a biomechanical process. While much of the chemistry has been worked out for both processes, the influence of biophysical properties is less well ...
Nearshore mixing and nutrient delivery along the western Antarctic Peninsula
(2017)
The surface waters of the Southern Ocean play a key role in the global climate and carbon cycles by promoting growth of some of the world’s largest phytoplankton blooms. Several studies have emphasized the importance of ...
A Content Analysis of Psychological Resilience Among First Responders and the General Population
(2017-03)
The current study examined how first responders and the general population described the concept of resilience. Categories
of resilience were coded a priori using Stemler’s content analysis. For the general population, ...
Lack of complex type N-glycans lessens aberrant neuronal properties
(2018-06)
Modifications in surface glycans attached to proteins via N-acetylglucosamine-β1-Nasparagine linkage have been linked to tumor development and progression. These modifications include complex N-glycans with high levels of ...
Sensor selection to improve estimates of particulate matter concentration from a low-cost network
(2018-09-08)
Deployment of low-cost sensors in the field is increasingly popular. However, each sensor requires on-site calibration to increase the accuracy of the measurements. We established a laboratory method, the Average Slope ...
N6-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression
(2018-07-27)
The mRNA modification N6-methyladenosine (m6A) is involved in many post-transcriptional regulatory processes including mRNA stability and translational efficiency. However, it is also imperative to correlate these processes ...
Emerging role of immune checkpoint blockade in pancreatic cancer
(2018-11-07)
Immune checkpoint blockade (ICB) with programmed cell death protein-1(PD-1)/programmed death ligand -1(PD-L1) antibodies has revolutionized the management of several cancers, especially non-small cell lung cancer, melanoma, ...
TNM cancer staging: can it help develop a novel staging system for type 2 diabetes?
(2018-11-28)
Type 2 diabetes (DM2) constitutes 90%–95% of the diabetes cases and is increasing at an alarming rate in the world. The Centers for Disease Control and Prevention (CDC) estimates that more than 29 million people in the ...