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Multi-walled carbon nanotube instillation impairs pulmonary function in C57BL/6 mice
(2011-08-18)
Multi-walled carbon nanotubes (MWCNTs) are widely used in many disciplines due to their unique physical and chemical properties. Therefore, some concerns about the possible human health and environmental impacts of ...
Metabolic remodeling of human skeletal myocytes by cocultured adipocytes depends on the lipolytic state of the system
(2011-06-20)
Adipocyte infiltration of the musculoskeletal system is well recognized as a hallmark of aging, obesity, and type 2 diabetes. Intermuscular adipocytes might serve as a benign storage site for surplus lipid or play a role ...
Is there a metabolic program in the skeletal muscle of obese individuals?
(2011-04-26)
Severe obesity (BMI ≥ 40 kg/m2) is associated with multiple defects in skeletal muscle which contribute to insulin resistance and a reduction in fatty acid oxidation (FAO) in this tissue. These metabolic derangements are ...
From imitation to innovation: A study of China's drug R&D and relevant national policies
(2011)
Research & Development (R&D) plays an increasingly important role in China's pharmaceutical industry. To gain a competitive edge in the global pharmaceutical market, the current national strategy of China forcefully pushes ...
Pain as a global public health priority
(2011-10-06)
Background
Pain is an enormous problem globally. Estimates suggest that 20% of adults suffer from pain globally and 10% are newly diagnosed with chronic pain each year. Nevertheless, the problem of pain has primarily been ...
In-training practice patterns of combined emergency medicine/internal medicine residents, 2003-2007
(2011-11)
This study seeks to evaluate the practice patterns of current combined emergency medicine/internal medicine (EM/IM) residents during their training and compare them to the typical practice patterns of EM/IM graduates. We ...
Association Between Health Literacy, Electronic Health Literacy, Disease-Specific Knowledge, and Health-Related Quality of Life Among Adults With Chronic Obstructive Pulmonary Disease: Cross-Sectional Study
(2019-06-06)
Background: Despite the relatively high prevalence of low health literacy among individuals living with chronic obstructive pulmonary disease (COPD), limited empirical attention has been paid to the cognitive and health ...
Conspecific brood parasitism in the tropics: An experimental investigation of host responses in common moorhens and American purple gallinules
(2011-08-03)
Species occupying a broad latitudinal range may show greater phenotypic plasticity in behavior than species with smaller ranges or more specific habitat requirements. This study investigates for the first time the occurrence ...
Synchronized Beta-Band Oscillations in a Model of the Globus Pallidus - Subthalamic Nucleus Network under External Input
(2016)
Hypokinetic symptoms of Parkinson’s disease are usually associated with the excessively strong oscillations and synchrony in the beta frequency band. The origin of this synchronized oscillatory dynamics is being debated. ...
Subcellular fractionation method to study endosomal trafficking of Kaposis sarcoma-associated herpesvirus
(2016)
Background: Virus entry involves multiple steps and is a highly orchestrated process on which successful infection
collectively depends. Entry processes are commonly analyzed by monitoring internalized virus particles via ...