Browsing Physics by Title
Now showing items 33-48 of 48
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A new assessment model for tumor heterogeneity analysis with [18]F-FDG PET images
(2016-01)It has been shown that the intratumor heterogeneity can be characterized with quantitative analysis of the [18]F-FDG PET image data. The existing models employ multiple parameters for feature extraction which makes it ... -
Optical and dielectric properties of metallic calcium, modeled generalized oscillator strength function of calcium, interaction cross sections of electrons, protons, and alpha particles with calcium
(East Carolina University, 2013)An analysis of the optical and the dielectric properties of calcium, determined from the literature, was performed. The optical functions of calcium were used for a calculation of the energy loss function of calcium. The ... -
Optical Pulling, Optical Deflection, and Optical Trapping of Single Airborne Particles using Negative Photophoresis
(East Carolina University, 2016-05-03)Optical manipulation is the use of light to control the motion of objects. This thesis focuses on the development of optical transportation technology via optical pulling with application to the characterization of single ... -
Optimizing graphene oxide reduction via laser irradiation
(East Carolina University, 2017-01-04)The present report discusses a single step method to reduce graphene oxide via laser irradiation. A computer numerically controlled laser engraver equipped with a 450nm laser diode was engineered to conduct this research. ... -
A PROPOSED METHODOLOGY TO ASSESS HDR [superscript]192Ir RADIAL DOSE WITH FRICKE DOSIMETRY
(East Carolina University, 2011)The radial absorbed dose to water, D(r,theta), a quantity not yet directly measured with primary standards, was assessed with the Fricke solution which has been considered as an absolute aqueous solution to perform dosimetry. ... -
Protection and Sensitization of Human Cells to Proton Radiation by Cerium Oxide Nanoparticles
(East Carolina University, 2017-07-17)In radiation therapy for the treatment of cancer, there is demand for novel approaches that will improve tumor cell killing while protecting healthy tissue. One such approach that has shown considerable promise is the ... -
Quantifying Double-Strand Breaks and Clustered Damages in DNA by Single-Molecule Laser Fluorescence Sizing
(East Carolina University, 2003-02)Fluorescence from a single DNA molecule passing through a laser beam is proportional to the size (contour length) of the molecule, and molecules of different sizes can be counted with equal efficiencies. Single-molecule ... -
Quantitative analysis and comparison of 3D morphology between viable and apoptotic MCF-7 breast cancer cells and characterization of nuclear fragmentation
(2017-09-08)Morphological changes in apoptotic cells provide essential markers for defining and detection of apoptosis as a fundamental mechanism of cell death. Among these changes, the nuclear fragmentation and condensation have ... -
Realistic optical cell modeling and diffraction imaging simulation for study of optical and morphological parameters of nucleus
(2016-01)Coherent light scattering presents complex spatial patterns that depend on morphological and molecular features of biological cells. We present a numerical approach to establish realistic optical cell models for generating ... -
Resolving power of diffraction imaging with an objective: a numerical study
(2017-05)Diffraction imaging in the far-field can detect 3D morphological features of an object for its coherent nature. We describe methods for accurate calculation and analysis of diffraction images of scatterers of single and ... -
Role of Dipicolinic Acid in the Germination, Stability, and Viability of Spores of Bacillus subtilis
(East Carolina University, 2008-07)Spores of Bacillus subtilis spoVF strains that cannot synthesize dipicolinic acid (DPA) but take it up during sporulation were prepared in medium with various DPA concentrations, and the germination and viability of these ... -
Secondary Electron Emission Yields from Fast Fluorine Ions on Copper and Amorphous Solid Water Foils
(East Carolina University, 2011)The biological outcomes from charged particle radiation exposure are heavily influenced by the spatial patterns of energy distributed within the biological system. Monte Carlo track structure codes can be used to model ... -
Study of Morphology Based Cell Assay by Diffraction Imaging Flow Cytometry
(East Carolina University, 2015)Development of an accurate and label-free method for single cell assay attracts intensive research efforts for its importance to cell biology research and clinicG14G7al applications. Flow cytometry is one of the most widely ... -
Superdormant Spores of Bacillus Species Have Elevated Wet-Heat Resistance and Temperature Requirements for Heat Activation
(East Carolina University, 2009-09)Purified superdormant spores of Bacillus cereus, B. megaterium, and B. subtilis isolated after optimal heat activation of dormant spores and subsequent germination with inosine, D-glucose, or L-valine, respectively, germinate ... -
Uptake of and Resistance to the Antibiotic Berberine by Individual Dormant, Germinating and Outgrowing Spores as Monitored by Laser Tweezers Raman Spectroscopy
(2015-12)Article Authors Metrics Comments Related Content Abstract Introduction Materials and Methods Results Discussion Supporting Information Acknowledgments Author Contributions References Reader Comments (0) Media ... -
VIABILITY OF CERIUM OXIDE NANOPARTICLES AS A RADIOPROTECTOR AGAINST PROTON RADIATION FOR NON-MALIGNANT CELLS
(East Carolina University, 2015)Radiation therapy is a prevalent cancer treatment therapy. The goal is to kill all tumor cells while minimizing damage to healthy cells and new methods that can accomplish this goal are continually being investigated. ...