Browsing Brody School of Medicine by Issue Date
Now showing items 61-80 of 1484
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The Ripped Cava
(East Carolina University, 1995-04)Lacerations of the inferior vena cava are associated with a high mortality and may be difficult to repair. The majority of injuries are due to penetrating trauma. Rapid transportation to definitive surgical care with ... -
Gastrogastric fistulas. A complication of divided gastric bypass surgery.
(East Carolina University, 1995-04)Objective This report warns that gastrogastric fistulas may follow the division of the stomach in bariatric surgery. Summary Background Data Although surgery is the most effective therapy for morbid obesity, the ... -
Equilibration and Exchange of Fluorescently Labeled Molecules in Skeletal Muscle Fibers Studied Using Confocal Microscopy
(East Carolina University, 1995-04)Diffusion of molecules into skinned muscle fibers is often necessary when studying muscle contraction and its regulation. Usually, it is assumed that diffusion of molecules is fast also in the structured system of a muscle ... -
Kinetics of Binding of Caldesmon to Actin
(East Carolina University, 1995-04-28)The time course of interaction of caldesmon with actin may be monitored by fluorescence changes that occur upon the binding of 12-(N-methyl-N-(7-nitrobenz-2-oxa-l,3-diazol-4-yl))-labeled caldesmon to actin or to acrylodan ... -
Biochemical and genetic analyses of a catalase from the anaerobic bacterium Bacteroides fragilis.
(East Carolina University, 1995-06)A single catalase enzyme was produced by the anaerobic bacterium Bacteroides fragilis when cultures at late log phase were shifted to aerobic conditions. In anaerobic conditions, catalase activity was detected ... -
Allopurinol improves myocardial reperfusion injury in a xanthine oxidase-free model
(East Carolina University, 1995-07)The ability of allopurinol to protect against reperfusion injury in the heart has usually been attributed to its xanthine oxidase (XO)- inhibiting properties. Human myocardium how- ever, has exhibited low levels of XO ... -
Cloning and characterization of a conjugated bile acid hydrolase gene from Clostridium perfringens.
(East Carolina University, 1995-07)The gene encoding a conjugated bile acid hydrolase (CBAH) from Clostridium perfringens 13 has been cloned and expressed in Escherichia coli, and its nucleotide sequence has been determined. Nucleotide and predicted amino ... -
Postvaccinial (influenza) disseminated encephalopathy (Brown-Sequard syndrome).
(East Carolina University, 1995-09)This article reports a case of Brown-Sequard syndrome that occurred in a patient following the administration of trivalent influenza vaccine. The patient responded well to intravenous steroids and physical therapy. This ... -
Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus.
(East Carolina University, 1995-09)OBJECTIVE: This report documents that the gastric bypass operation provides long-term control for obesity and diabetes. SUMMARY BACKGROUND DATA: Obesity and diabetes, both notoriously resistant to medical therapy, continue ... -
Phorbol esters induce death in MCF-7 breast cancer cells with altered expression of protein kinase C isoforms. Role for p53-independent induction of gadd-45 in initiating death.
(East Carolina University, 1995-10)Protein kinase C (PKC) modulates growth, differentiation, and apoptosis in a cell-specific fashion. Overexpression of PKC-a in MCF-7 breast cancer cells (MCF-7-PKC-a cell) leads to expression of a more transformed phenotype. ... -
Characterization of the avian GLUT1 glucose transporter: differential regulation of GLUT1 and GLUT3 in chicken embryo fibroblasts.
(East Carolina University, 1995-11)Vertebrate cells that are transformed by oncogenes such as v-src or are stimulated by mitogens have increased rates of glucose uptake. In rodent cels, the mechanisms whereby glucose transport is up-regulated are well ... -
The ornithine decarboxylase gene odc is required for alcaligin siderophore biosynthesis in Bordetella spp.: putrescine is a precursor of alcaligin.
(East Carolina University, 1996-01)Chromosomal insertions defining Bordetella bronchiseptica siderophore phenotypic complementation group III mutants BRM3 and BRM5 were found to reside approximately 200 to 300 bp apart by restriction mapping of cloned genomic ... -
Familial cryptic translocation resulting in Angelman syndrome:implications for imprinting or location of the Angelman gene?
(East Carolina University, 1996-04)Angelman syndrome (AS) is associated with a loss of maternal genetic information, which typically occurs as a result of a deletion at 15ql1-q13 or paternal uniparental disomy of chromosome 15. We report a patient with AS ... -
Attenuated viruses and method of making the same
(1996-04-18)Disclosed are attenuated viruses, not naturally occurring, that contain one or more additional methylation sites in the genome of the virus compared to the corresponding wild-type virus. Preferably, the methylation sites ... -
Method of inhibiting carcinogenesis by treatment with dehydroepiandrosterone and analogs thereof
(1996-06-18)A method of combatting cancer in a subject comprising administering to said subject dehydroepiandrosterone (DHEA) or an analog thereof in an amount effective to combat cancer is disclosed in which heart failure induced by ... -
Identification and characterization of iron-regulated Bordetella pertussis alcaligin siderophore biosynthesis genes.
(East Carolina University, 1996-08)Bordetella bronchiseptica mutants BRM1, BRM6, and BRM9 fail to produce the native dihydroxamate siderophore alcaligin. A 4.5-kb BamHI-SmaI Bordetella pertussis genomic DNA fragment carried multiple genes required to restore ... -
Method of treating asthma
(1996-09-10)A method of treating asthma in a subject in need of such treatment comprises contacting Asthma Reversal Factor to the respiratory epithelium of the subject. The active agent is preferably contacted to the subject's respiratory ... -
The nucleotide sequence of the Pseudomonas aeruginosa pyrE-crc-rph region and the purification of the crc gene product.
(East Carolina University, 1996-10)The gene (crc) responsible for catabolite repression control in Pseudomonas aeruginosa has been cloned and sequenced. Flanking the crc gene are genes encoding orotate phosphoribosyl transferase (pyrE) and RNase PH (rph). ...