Browsing Brody School of Medicine by Author "Kim, Kwonseop"
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14-3-3ɛ/ζ Affects the stability of δ-catenin and regulates δ-catenin-induced dendrogenesis
He, Yongfeng; Han, Jeong-Ran; Chang, Ockyoung; Oh, Minsoo; James, Sarah E.; Lu, Qun; Seo, Young-Woo; Kim, Hangun; Kim, Kwonseop (2012-11) -
delta-Catenin promotes prostate cancer cell growth and progression by altering cell cycle and survival gene profiles
Zeng, Yan; Abdallah, Agustin; Lu, Jian-Ping; Wang, Tao; Chen, Yan-Hua; Terrian, David M.; Kim, Kwonseop; Lu, Qun (East Carolina University, 2009-03-10)Background: delta-Catenin is a unique member of delta-catenin/armadillo domain superfamily proteins and its primary expression is restricted to the brain. However, delta-catenin is upregulated in human prostatic adenocarcinomas, ... -
E-Cadherin negatively modulates delta-catenin-induced morphological changes and RhoA activity reduction by competing with p190RhoGEF for delta-catenin
Kim, Hangun; Oh, Minsoo; Lu, Qun; Kim, Kwonseop (East Carolina University, 2008-12-12)δ-Catenin is a member of the p120-catenin subfamily of armadillo proteins. Here, we describe distinctive features of δ-catenin localization and its association with E-cadherin in HEK293 epithelial cells. In HEK293 cells ... -
Human homolog of airy and nhancer of plit 1, Hes1, negatively regulates δ-catenin () expression in cooperation with E2F1 in prostate cancer
Lu, Jian-Ping; Zhang, Jiao; Kim, Kwonseop; Case, Thomas C.; Matusik, Robert J.; Chen, Yan-Hua; Wolfe, Michael; Nopparat, Jongdee; Lu, Qun (2010) -
Identification of E2F1 as a positive transcriptional regulator for delta-catenin
Kim, Kwonseop; Oh, Minsoo; Ki, Hyunkyoung; Wang, Tao; Bareiss, Sonja; Fini, M. Elizabeth; Li, Dawei; Lu, Qun (East Carolina University, 2008-05-02)Delta-Catenin is upregulated in human carcinomas. However, little is known about the potential transcriptional factors that regulate delta-catenin expression in cancer. Using a human delta-catenin reporter system, we have ... -
Presenilin-1 inhibits delta-catenin-induced cellular branching and promotes delta-catenin processing and turnover
Kim, Jin-Sook; Bareiss, Sonja; Kim, Kyung Keun; Tatum, Rodney; Han, Jeong-Ran; Jin, Yun Hye; Kim, Hangun; Lu, Qun; Kim, Kwonseop (East Carolina University, 2006-12-29)Although delta-catenin/neural plakophilin-related armadillo protein (NPRAP) was reported to interact with presenilin-1 (PS-1), the effects of PS-1 on delta-catenin have not been established. In this study, we report that ...