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Fine Particulate air Pollution is Associated with Higher Vulnerability to Atrial Fibrillation—The APACR Study
(2011-04)
The acute effects and the time course of fine particulate pollution (PM2.5) on atrial fibrillation/flutter (AF) predictors, including P-wave duration, PR interval duration, and P-wave complexity, were investigated in a ...
Acute Effects of Fine Particulate Air Pollution on Cardiac Arrhythmia: The APACR Study
(2011-03)
Background: The mechanisms underlying the relationship between particulate matter (PM) air pollution and cardiac disease are not fully understood.
Objectives: We examined the effects and time course of exposure to fine ...
Robotics in Cardiac Surgery: Past, Present, and Future
(2013-07)
Robotic cardiac operations evolved from minimally invasive operations and offer similar theoretical benefits, including less pain, shorter length of stay, improved cosmesis, and quicker return to preoperative level of ...
Risk-Adjusted Survival after Coronary Artery Bypass Grafting: Implications for Quality Improvement
(2014-07)
Mortality represents an important outcome measure following coronary artery bypass grafting. Shorter survival times may reflect poor surgical quality and an increased number of costly postoperative complications. Quality ...
In-Training Practice Patterns of Combined Emergency Medicine/Internal Medicine Residents, 2003–2007
(2011-11)
Introduction
This study seeks to evaluate the practice patterns of current combined emergency medicine/internal medicine (EM/IM) residents during their training and compare them to the typical practice patterns of EM/IM ...
Regulation of Transglutaminase 2 structure and function by Ca²⁺ and [alpha]-synuclein
(East Carolina University, 2016-07-14)
Transglutaminase 2 (TG2) catalyzes the Ca2+-dependent transamidation of protein substrates between glutamine and lysine residues by formation of an N[epsilon]-([gamma]-L-glutamyl)-L-lysine isopeptide bond. The Ca2+-dependent ...
Medical and Household Characteristics Associated with Methicillin Resistant Nasal Carriage among Patients Admitted to a Rural Tertiary Care Hospital
(2013)
Background
Methicillin resistant Staphylococcus aureus (MRSA) poses a threat to patient safety and public health. Understanding how MRSA is acquired is important for prevention efforts. This study investigates risk ...
Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response
(2012-09)
The Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades are often activated by genetic alterations in upstream signaling molecules such as receptor tyrosine kinases (RTK). Certain components of these pathways, RAS, NF1, BRAF, ...
Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging
(2011-03)
Dysregulated signaling through the Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways is often the result of genetic alterations in critical components in these pathways or upstream activators. Unrestricted cellular proliferation ...
Advances in Targeting Signal Transduction Pathways
(2012-12)
Over the past few years, significant advances have occurred in both our understanding of the complexity of signal transduction pathways as well as the isolation of specific inhibitors which target key components in those ...