Browsing Open Access by Title
Now showing items 501-520 of 866
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MicroRNA profiling in the left atrium in patients with non-valvular paroxysmal atrial fibrillation
(2015)identifying miRNAs that were significantly associated with non-valvular paroxysmal AF. Methods: The RNA samples were isolated from healthy controls (n = 5) and patients with atrial fibrillation (n = 8). To confirm the ... -
MicroRNA-431 regulates axon regeneration in mature sensory neurons by targeting the Wnt antagonist Kremen1
(2013-10-24)MicroRNAs are small, non-coding RNAs that function as key post-transcriptional regulators in neural development, brain function and neurological diseases. Growing evidence indicates that microRNAs are also important mediators ... -
Microvascular Endothelial Dysfunction in Sedentary, Obese Humans Is Mediated by NADPH Oxidase Influence of Exercise Training
(2016)Objective—The objectives of this study were to determine the impact of in vivo reactive oxygen species (ROS) on microvascular endothelial function in obese human subjects and the efficacy of an aerobic exercise intervention ... -
Millipede taxonomy after 250 years: classification and taxonomic practices in a mega-diverse yet understudied arthropod group.
(2012-03-15)BACKGROUND: The arthropod class Diplopoda is a mega-diverse group comprising >12,000 described millipede species. The history of taxonomic research within the group is tumultuous and, consequently, has yielded a questionable ... -
miRNA-23a/27a attenuates muscle atrophy and renal fibrosis through muscle-kidney crosstalk
(2018-03-26)Background The treatment of muscle wasting is accompanied by benefits in other organs, possibly resulting from muscle– organ crosstalk. However, how the muscle communicates with these organs is less understood. Two microRNAs ... -
miRNA-36 inhibits KSHV, EBV, HSV-2 infection of cells via stifling expression of interferon induced transmembrane protein 1 (IFITM1)
(2017-12-21)Kaposi’s sarcoma-associated herpesvirus (KSHV) is etiologically associated with all forms of Kaposi’s sarcoma worldwide. Little is currently known about the role of microRNAs (miRNAs) in KSHV entry. We recently demonstrated ... -
Mismatched anti-predator behavioral responses in predator-naïve larval anurans
(2015)Organisms are adept at altering behaviors to balance the tradeoff between foraging and predation risk in spatially and temporally shifting predator environments. In order to optimize this tradeoff, prey need to be able to ... -
Mitigation Effect of Waste Glass Powders on Alkali–Silica Reaction (ASR) Expansion in Cementitious Composite
(2018-11-20)The effects of different contents and particle sizes of waste glass powder on alkali–silica reaction (ASR) expansion of cementitious composite bar were investigated in this study. Waste glass powder with particle size less ... -
Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity
(2019-09-11)Exercise capacity is a strong predictor of all-cause mortality. Skeletal muscle mitochondrial respiratory capacity, its biggest contributor, adapts robustly to changes in energy demands induced by contractile activity. ... -
Mitsui-7, heat-treated, and nitrogen-doped multi-walled carbon nanotubes elicit genotoxicity in human lung epithelial cells.
(2019-10-07)Background: The unique physicochemical properties of multi-walled carbon nanotubes (MWCNT) have led to many industrial applications. Due to their low density and small size, MWCNT are easily aerosolized in the workplace ... -
A mixed method analysis of patients' complaints: Underpinnings of theory-guided strategies to improve quality of care
(2018-10-10)Purpose: Patients' complaints can be predictors of patient care quality and safety. Understanding patients' complaints could help healthcare organizations target the areas for improvements. The purpose of this study is ... -
Ml proteins from Mesorhizobium loti and MucR from Brucella abortus: an AT-rich core DNA-target site and oligomerization ability
(2017-11-17)Mesorhizobium loti contains ten genes coding for proteins sharing high amino acid sequence identity with members of the Ros/MucR transcription factor family. Five of these Ros/MucR family members from Mesorhizobium loti ... -
Modeling of non-small cell lung cancer volume changes during CT-based image guided radiotherapy: Patterns observed and clinical implications
(2013-08-26)Background. To characterize the lung tumor volume response during conventional and hypofractionated radiotherapy (RT) based on diagnostic quality CT images prior to each treatment fraction. Methods. Out of 26 consecutive ... -
The Moderating Effect of Employee Political Skill on the Link between Perceptions of a Victimizing Work Environment and Job Performance
(2017-05-30)Research has generally revealed only a weak link, if any at all, between victimization- related experiences and job performance. Drawing on the commonly used conservation of resources perspective, we argue that such ... -
Molecular Connections between Cancer Cell Metabolism and the Tumor Microenvironment
(2015)Cancer cells preferentially utilize glycolysis, instead of oxidative phosphorylation, for metabolism even in the presence of oxygen. This phenomenon of aerobic glycolysis, referred to as the “Warburg effect”, commonly ... -
Molecular mechanisms of peripheral nerve regeneration: Emerging roles of microRNAs
(2013-04-01)microRNAs are small non-coding RNAs that suppress gene expression through target mRNA degradation or translation repression. Recent studies suggest that miRNA plays an important role in multiple physiological and pathological ... -
Molecular targeting of the Aurora-A/SMAD5 oncogenic axis restores chemosensitivity in human breast cancer cells
(2017-09-01)Although the majority of breast cancers initially respond to the cytotoxic effects of chemotherapeutic agents, most breast cancer patients experience tumor relapse and ultimately die because of drug resistance. Breast ... -
Monitoring Rice Phenology Based on Backscattering Characteristics of Multi-Temporal RADARSAT-2 Datasets
(2018-02-23)Accurate estimation and monitoring of rice phenology is necessary for the management and yield prediction of rice. The radar backscattering coefficient, one of the most direct and accessible parameters has been proved to ... -
Monopolar Detection Thresholds Predict Spatial Selectivity of Neural Excitation in Cochlear Implants: Implications for Speech Recognition
(2016)The objectives of the study were to (1) investigate the potential of using monopolar psychophysical detection thresholds for estimating spatial selectivity of neural excitation with cochlear implants and to (2) examine the ... -
The moral discourses of ‘post-crisis’ neoliberalism: a case study of Lithuania’s Labour Code reform
(2017-03)This article problematizes the neoliberal reconfiguration of labour rights in Lithuania, a newer European Union member state, in which the impacts of the global economic and financial crisis were particularly severe and ...