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Now showing items 1407-1426 of 3368

  • The Genetic Basis of Pigmentation Variation in Domesticated Zebra Finches 

    Pathak,Shaivya (2014)
    The zebra finch is the most common estrildid finch native to Australia and Southeast Asia. The zebra finch has also been domesticated and is now a common pet and experimental model system for research. As part of the ...

  • Genetic control of cell fate specification in Caenorhabditis elegans germline. 

    Mamillapalli, Srivalli Swathi (East Carolina University, 2015)
    The precise regulation of germ cell fates (sperm or oocyte) lies at the heart of reproduction and fertility. The nematode Caenorhabditis elegans hermaphrodites produce a discrete number of sperm during larval development ...

  • Genetic mapping of the female mimic morph locus in the ruff 

    Farrell, Lindsay L.; Burke, Terry; Slate, Jon; McRae, Susan B.; Lank, David B. (2013)
    Background Ruffs (Aves: Philomachus pugnax) possess a genetic polymorphism for male mating behaviour resulting in three permanent alternative male reproductive morphs: (i) territorial ‘Independents’, (ii) non-territorial ...

  • A Genetic Mosaic Screen Reveals Ecdysone-Responsive Genes Regulating Drosophila Oogenesis 

    Ables, Elizabeth Tweedie; Hwang, Grace H.; Finger, Danielle S.; Hinnant, Taylor D.; Drummond-Barbosa, Daniela (2016-08)
    Multiple aspects of Drosophila oogenesis, including germline stem cell activity, germ cell differentiation, and follicle survival, are regulated by the steroid hormone ecdysone. While the transcriptional targets of ecdysone ...

  • Genetic Organization and Iron-Responsive Regulation of the Brucella abortus 2,3-Dihydroxybenzoic Acid Biosynthesis Operon, a Cluster of Genes Required for Wild-Type Virulence in Pregnant Cattle 

    Bellaire, Bryan H.; Elzer, Philip H.; Hagius, Sue; Walker, Joel; Baldwin, Cynthia L.; Roop, R. Martin II (East Carolina University, 2003-04)
    Brucella abortus reportedly produces the monocatechol siderophore 2,3-dihydroxybenzoic acid (2,3-DHBA) in response to iron limitation. Nucleotide sequence analysis of the cloned DHBA biosynthesis locus from virulent B. ...

  • A Genetic Screen for Mcm10: Interactions Between Mcm10 and Deficiency Regions on the Third Chromosome of Drosophila Melanogaster 

    Anstead, Bryan (2015)
    Mis-regulation of the Mcm10 gene has been linked with multiple forms of cancer, including many forms of breast cancer (Thu, Y. 2014). Despite this, the role of Mcm10 in cancer is not yet fully known. One way to study a ...

  • Genetic variation corroborates subspecific delimitation in the Namib fog-basking beetle, (Haag) (Tenebrionidae, Coleoptera) 

    Lamb, Trip; Pollard, Rachel; Bond, Jason E. (2013)
    The fog-basking beetle, Onymacris unguicularis (Haag, 1875), is currently listed as a polytypic form comprising two subspecies. A flightless substrate specialist, the beetleis endemic to vegetationless dunes in the Namib, ...

  • Genome Analysis of Planctomycetes Inhabiting Blades of the Red Alga 

    Kim, Jay W.; Brawley, Susan H.; Prochnik, Simon; Chovatia, Mansi; Grimwood, Jane; Jenkins, Jerry W.; LaButti, Kurt; Mavromatis, Konstantinos; Nolan, Matt; Zane, Matthew; Schmutz, Jeremy; Stiller, John W.; Grossman, Arthur R. (2016-03)
    Porphyra is a macrophytic red alga of the Bangiales that is important ecologically and economically. We describe the genomes of three bacteria in the phylum Planctomycetes (designated P1, P2 and P3) that were isolated from ...

  • Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome 1q in African-American pedigrees 

    Moser, Kathy L.; Neas, Barbara R.; Salmon, Jane E.; Yu, Hua; Gray-McGuire, Courtney; Asundi, Neeraj; Bruner, Gail R.; Fox, Jerome; Kelly, Jennifer; Henshall, Stephanie; Bacino, Debra; Dietz, Myron; Hogue, Robert; Koelsch, Gerald; Nightingale, Lydia; Shaver, Tim; Abdou, Nabih I.; Albert, Daniel A.; Carson, Craig; Petri, Michelle; Treadwell, Edward L.; James, Judith A.; Harley, John B. (East Carolina University, 1998-12)
    Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by production of autoantibodies against intracellular antigens including DNA, ribosomal P, Ro (SS-A), La (SS-B), and the spliceosome. Etiology is ...

  • Genome Sequence Analysis of Dengue Virus 1 Isolated in Key West, Florida 

    Shin, Dongyoung; Richards, Stephanie L.; Alto, Barry W.; Bettinardi, David J.; Smartt, Chelsea T. (2013)
    Dengue virus (DENV) is transmitted to humans through the bite of mosquitoes. In November 2010, a dengue outbreak was reported in Monroe County in southern Florida (FL), including greater than 20 confirmed human cases. The ...

  • Genome sequencing and analysis of the paclitaxel-producing endophytic fungus NRRL 62431 

    Yang, Yanfang; Zhao, Hainan; Barrero, Roberto A; Zhang, Baohong; Sun, Guiling; Wilson, Iain W.; Xie, Fuliang; Walker, Kevin D; Parks, Joshua W; Bruce, Robert; Guo, Guangwu; Chen, Li; Zhang, Yong; Huang, Xin; Tang, Qi; Liu, Hongwei; Bellgard, Matthew I; Qiu, Deyou; Lai, Jinsheng; Hoffman, Angela (2014)
    Background Paclitaxel (Taxol™) is an important anticancer drug with a unique mode of action. The biosynthesis of paclitaxel had been considered restricted to the Taxus species until it was discovered in Taxomyces andreanae, ...

  • Genome-wide and molecular evolution analysis of the subtilase gene family in 

    Cao, Jun; Han, Xi; Zhang, Ticao; Yang, Yongping; Huang, Jinling; Hu, Xiangyang (2014-12)
    Background Vitis vinifera (grape) is one of the most economically significant fruit crops in the world. The availability of the recently released grape genome sequence offers an opportunity to identify and analyze some ...

  • Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia 

    Zhang, Yong-Biao; Hu, Jintian; Zhang, Jiao; Zhou, Xu; Li, Xin; Gu, Chaohao; Liu, Tun; Xie, Yangchun; Liu, Jiqiang; Gu, Mingliang; Wang, Panpan; Wu, Tingting; Qian, Jin; Wang, Yue; Dong, Xiaoqun; Yu, Jun; Zhang, Qingguo (2016-02)

  • Genome-Wide Functional Analysis of the Cotton Transcriptome by Creating an Integrated EST Database 

    Xie, Fuliang; Sun, Guiling; Stiller, John W.; Zhang, Baohong (2011)
    A total of 28,432 unique contigs (25,371 in consensus contigs and 3,061 as singletons) were assembled from all 268,786 cotton ESTs currently available. Several in silico approaches [comparative genomics, Blast, Gene Ontology ...

  • Genome-Wide Identification And Expression Analysis Of TCP Transcription Factors In Cotton 

    Ma, Jun (East Carolina University, 2015)
    TCP proteins are plant-specific transcription factors known to perform a variety of physiological functions during plant growth and development. In the current study, we performed for the first time the comprehensive ...

  • Genome-Wide Identification of R2R3-MYB Genes and Expression Analyses During Abiotic Stress in 

    He, Qiuling; Jones, Don C.; Li, Wei; Xie, Fuliang; Ma, Jun; Sun, Runrun; Wang, Qinglian; Zhu, Shuijin; Zhang, Baohong (2016-03)
    The R2R3-MYB is one of the largest families of transcription factors, which have been implicated in multiple biological processes. There is great diversity in the number of R2R3-MYB genes in different plants. However, there ...

  • Genome-Wide Meta-Analysis of Homocysteine and Methionine Metabolism Identifies Five One Carbon Metabolism Loci and a Novel Association of with Ischemic Stroke 

    Williams, Stephen R.; Yang, Qiong; Chen, Fang; Liu, Xuan; Keene, Keith L.; Jacques, Paul; Chen, Wei-Min; Weinstein, Galit; Hsu, Fang-Chi; Beiser, Alexa; Wang, Liewei; Bookman, Ebony; Doheny, Kimberly F.; Wolf, Philip A.; Zilka, Michelle; Selhub, Jacob; Nelson, Sarah; Gogarten, Stephanie M.; Worrall, Bradford B.; Seshadri, Sudha; Sale, Michèle M. (2014-03)
    Circulating homocysteine levels (tHcy), a product of the folate one carbon metabolism pathway (FOCM) through the demethylation of methionine, are heritable and are associated with an increased risk of common diseases such ...

  • Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer 

    Di, Li-Jun; Byun, Jung S.; Wong, Madeline M.; Wakano, Clay; Taylor, Tara; Bilke, Sven; Baek, Songjoon; Hunter, Kent; Yang, Howard; Lee, Maxwell; Zvosec, Celia; Khramtsova, Galina; Cheng, Fan; Perou, Charles M.; Miller, C. Ryan; Raab, Rachel; Olopade, Olufunmilayo I.; Gardner, Kevin (http://www.ncbi.nlm.nih.gov/pubmed/23385593, 2013-1)

  • The genomes of two key bumblebee species with primitive eusocial organization 

    Sadd, Ben M.; Barribeau, Seth M.; Bloch, Guy; de Graaf, Dirk C.; Dearden, Peter; Elsik, Christine G.; Gadau, Jürgen; Grimmelikhuijzen, Cornelis J.; Hasselmann, Martin; Lozier, Jeffrey D.; Robertson, Hugh M.; Smagghe, Guy; Stolle, Eckart; Van Vaerenbergh, Matthias; Waterhouse, Robert M.; Bornberg-Bauer, Erich; Klasberg, Steffen; Bennett, Anna K.; Câmara, Francisco; Guigó, Roderic; Hoff, Katharina; Mariotti, Marco; Munoz-Torres, Monica; Murphy, Terence; Santesmasses, Didac; Amdam, Gro V.; Beckers, Matthew; Beye, Martin; Biewer, Matthias; Bitondi, Márcia M.; Blaxter, Mark L.; Bourke, Andrew F.; Brown, Mark J. F.; Buechel, Severine D.; Cameron, Rossanah; Cappelle, Kaat; Carolan, James C.; Christiaens, Olivier; Ciborowski, Kate L.; Clarke, David F.; Colgan, Thomas J.; Collins, David H.; Cridge, Andrew G.; Dalmay, Tamas; Dreier, Stephanie; du Plessis, Louis; Duncan, Elizabeth; Erler, Silvio; Evans, Jay D.; Falcon, Tiago; Flores, Kevin; Freitas, Flávia C.; Fuchikawa, Taro; Gempe, Tanja; Hartfelder, Klaus; Hauser, Frank; Helbing, Sophie; Humann, Fernanda C.; Irvine, Frano; Jermiin, Lars S.; Johnson, Claire E.; Johnson, Reed M.; Jones, Andrew K; Kadowaki, Tatsuhiko; Kidner, Jonathan H.; Koch, Vasco; Köhler, Arian; Kraus, F. B.; Lattorff, H. M. G.; Leask, Megan; Lockett, Gabrielle A.; Mallon, Eamonn B.; Antonio, David S. Marco; Marxer, Monika; Meeus, Ivan; Moritz, Robin F.; Nair, Ajay; Näpflin, Kathrin; Nissen, Inga; Niu, Jinzhi; Nunes, Francis M.; Oakeshott, John G.; Osborne, Amy; Otte, Marianne; Pinheiro, Daniel G.; Rossié, Nina; Rueppell, Olav; Santos, Carolina G.; Schmid-Hempel, Regula; Schmitt, Björn D.; Schulte, Christina; Simões, Zilá L.; Soares, Michelle P.; Swevers, Luc; Winnebeck, Eva C.; Wolschin, Florian; Yu, Na; Zdobnov, Evgeny M.; Aqrawi, Peshtewani K.; Blankenburg, Kerstin P.; Coyle, Marcus; Francisco, Liezl; Hernandez, Alvaro G.; Holder, Michael; Hudson, Matthew E.; Jackson, LaRonda; Jayaseelan, Joy; Joshi, Vandita; Kovar, Christie; Lee, Sandra L.; Mata, Robert; Mathew, Tittu; Newsham, Irene F.; Ngo, Robin; Okwuonu, Geoffrey; Pham, Christopher; Pu, Ling-Ling; Saada, Nehad; Santibanez, Jireh; Simmons, DeNard; Thornton, Rebecca; Venkat, Aarti; Walden, Kimberly K.; Wu, Yuan-Qing; Debyser, Griet; Devreese, Bart; Asher, Claire; Blommaert, Julie; Chipman, Ariel D.; Chittka, Lars; Fouks, Bertrand; Liu, Jisheng; O’Neill, Meaghan P.; Sumner, Seirian; Puiu, Daniela; Qu, Jiaxin; Salzberg, Steven L.; Scherer, Steven E.; Muzny, Donna M.; Richards, Stephen; Robinson, Gene E.; Gibbs, Richard A.; Schmid-Hempel, Paul; Worley, Kim C. (2015-04-24)
    Background The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies. ...

  • Geochemistry and Genesis of Late Paleoproterozoic Banded Iron Formations and Metamorphosed Chemical Precipitates Spatially Associated with Pb-Zn Broken Hill-type Mineralization near the Broken Hill Deposit, Curnamona Province, Australia 

    Serna, Erica (East Carolina University, 2014)
    Banded and massive iron formations (IFs) and garnet- and gahnite-quartz rocks are spatially associated with the giant, late Paleoproterozoic, Pb-Zn-Ag Broken Hill sulfide deposit and hundreds of minor Broken Hill-type ...