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Effectiveness of a Total Meal Replacement Program (OPTIFAST Program) on Weight Loss: Results from the OPTIWIN Study
(2018-11-13)
Objective: The aim of this study was to test the effectiveness of the OPTIFAST program (OP), a total meal replacement dietary intervention, compared with a food-based (FB) dietary plan for weight loss. Methods: Participants ...
Time course metabolome of Roux-en-Y gastric bypass confirms correlation between leptin, body weight and the microbiome
(2018-05-31)
Roux-en-Y gastric bypass (RYGB) is an effective way to lose weight and reverse type 2 dia- betes. We profiled the metabolome of 18 obese patients (nine euglycemic and nine diabet- ics) that underwent RYGB surgery and seven ...
Is there a metabolic program in the skeletal muscle of obese individuals?
(2011-04-26)
Severe obesity (BMI ≥ 40 kg/m2) is associated with multiple defects in skeletal muscle which contribute to insulin resistance and a reduction in fatty acid oxidation (FAO) in this tissue. These metabolic derangements are ...
Prospective Study Examining Clinical Outcomes Associated with a Negative Pressure Wound Therapy System and Barker’s Vacuum Packing Technique
(2013-05)
Background
The open abdomen has become a common procedure in the management of complex abdominal problems and has improved patient survival. The method of temporary abdominal closure (TAC) may play a role in patient ...
An Unusual Presentation of a Posterior Mediastinal Schwannoma Associated with Traumatic Hemothorax
(2015)
Schwannomas of the thoracic cavity are typically an asymptomatic, benign neurogenic neoplasm of the posterior mediastinum. In this case, we present a traumatic hemothorax as the initial presentation for a previously ...
Hypothermia in trauma patients: predicting the big chill
(2012)
Physicians commonly ignore hypothermia, an often-underappreciated event associated with mortality in trauma patients, in general due to its prevalence and belief that it is secondary to the injury itself (secondary ...
Course of Depressive Symptoms and Treatment in the Longitudinal Assessment of Bariatric Surgery (LABS-2) Study
(2014-05)
Objective
To examine changes in depressive symptoms and treatment in the first three years following bariatric surgery.
Design and Methods
The Longitudinal Assessment of Bariatric Surgery-2 is an observational ...
S.O.S.
(2012-12)
The concept that type 2 diabetes mellitus (T2DM) can be reversed with an intestinal operation is counterintuitive. How could our costliest disease be forced into full, durable, and safe remission with the bypass of a few ...
The Short-Term Effect of Weight Loss Surgery on Volumetric Breast Density and Fibroglandular Volume
(2016-10-26)
Purpose:
Obesity and breast density are both associated with an increased risk of breast cancer and are potentially modifiable. Weight loss surgery (WLS) causes a significant reduction in the amount of body fat and a ...