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Wetland management strategies lead to tradeoffs in ecological structure and function
(2017-12)
Anthropogenic legacy effects often occur as a consequence of land use change or land management and can leave behind long-lasting changes to ecosystem structure and function. This legacy is described as a memory in the ...
Impaired T cell-mediated hepatitis in peroxisome proliferator activated receptor alpha (PPARα)-deficient mice
(2018-02-15)
Background
Peroxisome proliferator activated receptor alpha (PPARα), a regulator of enzymes involved in β oxidation, has been reported to influence lymphocyte activation. The purpose of this study was to determine whether ...
protaTETHER – a method for the incorporation of variable linkers in protein fusions reveals impacts of linker flexibility in a PKAc‐GFP fusion protein
(2018-03-14)
Protein fusions are of fundamental importance in the study of cellular biology and the elucidation of cell signaling pathways, and the importance of linkers for the proper function of protein fusions is well documented in ...
Factors Affecting Patient Portal Use Among Low-Income Pregnant Women: Mixed-Methods Pilot Study
(2018-03)
Background: Patient portals offer patients personalized and secure Web access to their medical information and enable patients to manage their health care online. However, there is a lack of information about patient ...
Recommendations for active correction of hypernatremia in volume-resuscitated shock or sepsis patients should be taken with a grain of salt: A systematic review
(2018-03-21)
Background: Healthcare-acquired hypernatremia (serum sodium >145 mEq/dL) is common among critically ill and other
hospitalized patients and is usually treated with hypotonic fluid and/or diuretics to correct a “free water ...
PI3K mediated activation of GSK‑3β reduces at‑level primary afferent growth responses associated with excitotoxic spinal cord injury dysesthesias
(2015-06-21)
Background
Neuropathic pain and sensory abnormalities are a debilitating secondary consequence of spinal cord injury (SCI). Maladaptive structural plasticity is gaining recognition for its role in contributing to the ...
Lexical diversity in Parkinson’s disease
(2015-03-02)
Background: Parkinson’s disease (PD) is a neurodegenerative syndrome of the basal ganglia (BG) believed to disrupt cortical-subcortical pathways critical to motor, cognitive and expressive language function. Recent studies ...
A CRISPR/Cas9 Toolbox for Multiplexed Plant Genome Editing and Transcriptional Regulation
(2015)
The relative ease, speed and biological scope of CRISPR/Cas9-based reagents for genomic manipulations are revolutionizing virtually all areas of molecular biosciences, including functional genomics, genetics, applied ...
Which Resources Matter? : Resources And The Impact Of North Carolina Environmental Organizations
(East Carolina University, 2015)
This paper focuses on the role that resources have in predicting the impact of an environmental organizations. This study contributes to an emerging stream of research literature on social movements that explicitly uses ...
Analysis of the Maize dicer-like1 Mutant, fuzzy tassel, Implicates MicroRNAs in Anther Maturation and Dehiscence
(2016-01-08)
Sexual reproduction in plants requires development of haploid gametophytes from somatic tissues. Pollen is the male gametophyte and develops within the stamen; defects in the somatic tissues of the stamen and in the male ...