Browsing Health Sciences Campus by Title
Now showing items 902-921 of 1574
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MCF-7 breast cancer cells transfected with protein kinase C-alpha exhibit altered expression of other protein kinase C isoforms and display a more aggressive neoplastic phenotype.
(East Carolina University, 1995-04)Increased protein kinase C (PKC) activity in malignant breast tissue and positive correlations between PKC activity and expression of a more aggressive phenotype in breast cancer cell lines suggest a role for this signal ... -
Measles vaccine vectors and methods of use
(2003-03-20)The present invention provides a novel vaccine expressing a fusion of the measles hemagglutinin (H) protein and the complement component, C3d, to enhance the titers of neutralizing antibody. Plasmids were generated that ... -
MEASUREMENT OF WORD RETRIEVAL IN THE DISCOURSE OF PERSONS WITH APHASIA: STANDARD CORE LEXICON ITEM DEVELOPMENT AND PSYCHOMETRIC PROPERTIES
(East Carolina University, 8/5/2020)Core lexicon measures are a quantitative measure of lexical use in discourse for persons with aphasia. It is intended to provide clinicians with a clinician-friendly means to quantify lexical use in discourse based on ... -
Measures of the Consumer Food Store Environment: A Systematic Review of the Evidence 2000–2011
(2011-12)Description of the consumer food environment has proliferated in publication. However, there has been a lack of systematic reviews focusing on how the consumer food environment is associated with the following: (1) ... -
Mechanism for Improved Insulin Sensitivity after Gastric Bypass Surgery
(East Carolina University, 2008-12)Context: Surgical treatments of obesity have been shown to induce rapid and prolonged improvements in insulin sensitivity. Objective: The aim of the study was to investigate the effects of gastric bypass surgery and the ... -
Mechanisms controlling the acquisition of a cardiac phenotype by liver stem cells
(East Carolina University, 2007-03-06)The mechanisms underlying stem cell acquisition of a cardiac phenotype are unresolved. We studied early events during the acquisition of a cardiac phenotype by a cloned adult liver stem cell line (WB F344) in a cardiac ... -
Mechanisms for central cannabinoid receptor 1 evoked sympathoexcitation/pressor response in conscious rats
(East Carolina University, 2010)The main goal of the current study was to elucidate the molecular mechanisms implicated in central cannabinoid receptor 1 (CB1R)-evoked sympathoexcitation/pressor response. In pursuit of this goal, the candidate first ... -
Mechanisms Involved in the Cerebrovascular Dilator Effects of N-methyl-D-aspartate in Cerebral Cortex
(East Carolina University, 2007-11)Glutamate and its synthetic analogues N-methyl-D-aspartate (NMDA), kainate, and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) are potent dilator agents in the cerebral circulation. The close linkage between ... -
MECHANISMS OF LEFT VENTRICULAR REMODELING IN PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS
(East Carolina University, 8/5/2020)Cardiac remodeling is composed of molecular, cellular, and interstitial changes in the cardiac tissue that affect the size, shape, and function of the heart. There are two types of cardiac remodeling: physiological and ... -
Mechanistic analysis of a synthetic inhibitor of the LasI quorum-sensing signal synthase
(2015-11)Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen responsible for many human infections. LasI is an acyl-homoserine lactone synthase that produces a quorum-sensing (QS) signal that positively regulates ... -
Mediastinal neoplasms in patients with Graves disease: a possible link between sustained hyperthyroidism and thymic neoplasia?
(2012)Background Anterior mediastinal masses are a rare but well documented finding in Graves disease. The vast majority of these lesions represents benign thymic hypertrophy and regress after treatment of the hyperthyroidism. ... -
Medical and Household Characteristics Associated with Methicillin Resistant Nasal Carriage among Patients Admitted to a Rural Tertiary Care Hospital
(2013)Background Methicillin resistant Staphylococcus aureus (MRSA) poses a threat to patient safety and public health. Understanding how MRSA is acquired is important for prevention efforts. This study investigates risk ... -
The Medical Library as a Component of a Medical School Outreach Experience
(2020-01)The US is facing a shortage of physicians for minorities and patients in disadvantaged areas. Many medical schools have pipeline programs to promote the interest of minority students in medicine. The Brody School of ... -
The Medical Library as a Component of a Medical School Pipeline Program
(2019-10-05)The US is facing a shortage of physicians for minorities and patients in disadvantaged areas. Many medical schools have pipeline programs to promote the interest of minority students in medicine. The Brody School of Medicine ... -
Medication Deprescribing at End of Life in the Long-Term Care Population
(2020-07-26)Polypharmacy, generally defined as taking five or more medications, is the leading cause of adverse drug events for older patients and affects as many as 95% of patients residing in long-term care. Nearly half of all ... -
MEDLINE via PubMed Search Strategy for Cox et al., A systematic review of high-risk environmental circumstances for adolescent drinking
(2018-09-26)This is the MEDLINE via PubMed search strategy used to identify articles for a systematic review examining the environmental context of high-risk adolescent alcohol consumption. The search strategy was mapped across other ... -
Meeting the Challenge of Providing Nutrition Services During the COVID-19 Pandemic.
(2021-01)Examples of Registered Dietitian Nutritionists (RDNs) who used their abilities to innovate and adapt to ensure the public, their patients and clients received continuous nutrition services, weight management services, ... -
Melting Away: Sifting through the Special Snowflakes
(2018-11-07)Medical practice books tend to become quickly outdated as clinical practice changes with ever-evolving research. For the past few years, Laupus Health Sciences Library has been ordering eBooks in addition to ordering books ... -
Mental Health Professionals' Attitudes toward Clients with Antisocial Personality Disorder
(East Carolina University, 2017-04-19)Clients with personality disorder are treated throughout the United States' healthcare system. Research suggests that mental health professionals' attitudes' toward clients with personality disorders are poor. However, ... -
Metformin Improves Insulin Signaling in Obese Rats via Reduced IKK Action in a Fiber-Type Specific Manner
(2010)Metformin is a widely used insulin-sensitizing drug, though its mechanisms are not fully understood. Metformin has been shown to activate AMPK in skeletal muscle; however, its effects on the inhibitor of κB kinaseβ (IKKβ) ...