Browsing Open Access by Title
Now showing items 692-711 of 866
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Response and resilience of Spartina alterniflora to sudden dieback
(2016-08)We measured an array of biophysical and spectral variables to evaluate the response and recovery of Spartina alterniflora to a sudden dieback event in spring and summer 2004 within a low marsh in coastal Virginia, USA. S. ... -
Response of high-risk MDS to azacitidine and lenalidomide is impacted by baseline and acquired mutations in a cluster of three inositide-specific genes
(2019-02-20)Specific myeloid-related and inositide-specific gene mutations can be linked to myelodysplastic syndromes (MDS) pathogenesis and therapy. Here, 44 higher-risk MDS patients were treated with azacitidine and lenalidomide and ... -
Resume, Eulogy, Education and Future
(2017-10)Will the current trend of the Industrial Age, focused on profits, greed, material wealth, and mass consumption continue? Inequality and polarization, which are seen in today’s world, are ranked as the top drivers of global ... -
Resumption of Immune Checkpoint Inhibitor Therapy After Immune-Mediated Colitis
(2019-10-20)PURPOSE: Immune checkpoint inhibitor (ICI) therapy often is suspended because of immune-mediated diarrhea and colitis (IMDC). We examined the rate of and risk factors for IMDC recurrence after ICI resumption. METHODS: ... -
Resurrection of the Body and Cryonics
(2017-05-18)The Christian doctrine of resurrection of the body is employed to interpret the cryonics program of preserving legally dead people with the plan to restore them when future medicine can effectively address the cause of ... -
Resveratrol inhibits KSHV reactivation by lowering the levels of cellular Egr-1
(2012-03-12)In the field of herpesvirus research, the exact molecular mechanism by which such viruses reactivate from latency remains elusive. Kaposi's sarcoma-associated herpesvirus (KSHV) primarily exists in a latent state, while ... -
Reuse of a previously transplanted kidney: Does success come with a price?
(2012-10)Longer wait times for deceased donor kidney transplant have prompted newer initiatives to expedite the process. Reuse of a previously transplanted kidney might be appropriate in certain circumstances. However, one must ... -
A Review of Studies Evaluating Insecticide Barrier Treatments for Mosquito Control From 1944 to 2018
(2019-06-26)Background and Purpose: Barrier insecticide treatments have a long history in mosquito control programs but have been used more frequently in the United States in recent years for control of invasive “backyard” species ... -
Revisiting maine's lobster commons: Rescaling political subjects
(2012)Calls for cross-scalar theoretical and methodological approaches are not new to commons scholarship. Such efforts might be hastened by channelling poststructuralist and critical theory perspectives through the geographic ... -
Rho GTPases as therapeutic targets in Alzheimer’s disease
(2017-12-15)The progress we have made in understanding Alzheimer’s disease (AD) pathogenesis has led to the identification of several novel pathways and potential therapeutic targets. Rho GTPases have been implicated as critical ... -
RhoGTPase Regulators Orchestrate Distinct Stages of Synaptic Development
(2017-01-23)Small RhoGTPases regulate changes in post-synaptic spine morphology and density that support learning and memory. They are also major targets of synaptic disorders, including Autism. Here we sought to determine whether ... -
Risk factors associated with physical and mental distress in people who report a COPD diagnosis: latent class analysis of 2016 behavioral risk factor surveillance system data
(2019-04-10)Introduction: Challenges associated with COPD increase patients’ risk of physical immobility and emotional distress, perpetuating a cycle of symptomatic living that hinders patients’ self-management and adherence to a ... -
Risk Factors for Stunting in Children under the Age of 5 in Rural Guatemalan Highlands
(2020-02-03)Background: Previously, a study conducted by UNICEF found that malnutrition affects approximately 80% of the indigenous children in Guatemala. Objective: Identify prevalence and risk factors for stunted growth in ... -
Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer:5-year results for local control and overall survival from the TARGIT-A randomised trial
(2014-02-14)The TARGIT-A trial compared risk-adapted radiotherapy using single-dose targeted intraoperative radiotherapy (TARGIT) versus fractionated external beam radiotherapy (EBRT) for breast cancer. We report 5-year results for ... -
Rituximab therapy in pulmonary alveolar proteinosis improves alveolar macrophage lipid homeostasis
(2012-06-14)Pulmonary Alveolar Proteinosis (PAP) patients exhibit an acquired deficiency of biologically active granulocyte-macrophage colony stimulating factor (GM-CSF) attributable to GM-CSF specific autoantibodies. PAP alveolar ... -
The role of fishing material culture in communities’ sense of place as an added-value in management of coastal areas
(2016)Fishing communities in many places around the world are facing significant challenges due to new policies and environmental developments. While it is imperative to ensure sustainability of natural resources, many policies ... -
The role of PPARγ in carbon nanotube-elicited granulomatous lung inflammation
(2013-01-23)Background Although granulomatous inflammation is a central feature of many disease processes, cellular mechanisms of granuloma formation and persistence are poorly understood. Carbon nanoparticles, which can be products ... -
The Role of Retinoic Acid (RA) in Spermatogonial Differentiation
(2016)Retinoic acid (RA) directs the sequential, but distinct, programs of spermatogonial differentiation and meiotic differentiation that are both essential for the generation of functional spermatozoa. These processes are ... -
Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells
(2017-02)Various signaling pathways exert critical roles in the epithelial to mesenchymal transition (EMT) and cancer stem cells (CSCs). The Wnt/beta-catenin, PI3K/PTEN/ Akt/mTORC, Ras/Raf/MEK/ERK, hedgehog (Hh), Notch and TP53 ...